Under Construction

This page is currently under construction. Soon you will find further information about SAIL here.

SAIL - Small Animal Imaging Lübeck

A central imaging facility dedicated to small animal imaging is currently being set up in the basement of the CBBM research building (Campus University of Lübeck / UKSH Lübeck).

It will include S2 (biosafety level 2) laboratories dedicated to the following imaging methods:

  • Optical Imaging (multi-photon microscopy, optical coherence microscopy)
  • Magnetic Particle Imaging
  • Magnetic Resonance Imaging
  • Multimodal Positron Emission Tomography / Computed Tomography

Animal care rooms will be available for the animals under study. A separate animal care room will be dedicated to radioactive animals.

MPI Magnetic Particle Imaging

  • Purpose: visualize magnetic nanoparticle tracers in blood vessels
  • Animal size: rats and mice
  • Status: installed
  • System: Bruker
  • Strengths: speed, sensitivity

MRI - Magnetic Resonance Imaging

  • Purpose: reference images for MPI studies, independent soft tissue studies
  • Strengths: soft tissue contrast, access to diffusion, contrast agent distribution

Contact: Martin Koch

PET/CT - Positron Emission Tomography / Computed Tomography

  • Purpose PET: visualize and quantify the spatial and temporal distribution of specific radiopharmaceuticals and other substances radiolabelled in situ.
  • Purpose CT: visualize anatomy and morphological changes
  • Strengths: „molecular imaging“, in vivo functional information, anatomy (CT)

Optical Intravital Imaging

  • Purpose: Intravital imaging at sub-cellular resolution (surface / mm-depth)
  • Status: Several systems for optical coherence (OCT) and  multi-photon microscopy are already working under S1/S2 conditions in the BMO and CBBM; RAMAN microscopy for molecular contrast and endoscopic devices are being developed
  • Strengths: Sub-cellular resolution, specific staining as well as endogenous contrast available for morphological and functional imaging;  translation to clinical diagnosis possible