Prof. Dr. rer. nat. Martin Koch

Photo of Martin  Koch

Institut für Medizintechnik
Universität zu Lübeck
Ratzeburger Allee 160
23562 Lübeck
Gebäude 64, Raum 061

Email: martin.koch(at)uni-luebeck.de
Phone: +49 451 3101 5411
Fax: +49 451 3101 5404


Research Interests

  • Magnetic Resonance Imaging
  • Diffusion
  • Neuroscience
  • Functional Magnetic Resonance

Curriculum Vitae

Born in Dinslaken, Germany, in 1968. 1992 to 1995 study of Physics at Göttingen University. 1992/1993 studies at University of Edinburgh, Scotland, UK. 1995 degree Diplom-Physiker, Georg-August-Universität Göttingen (Thesis "Infrared Spectroscopy of Size-Selected Amino Acid Clusters", Max Planck Institute for Flow Research, Göttingen). 1996-2000 PhD project (Measurement of the Self-Diffusion Tensor of Water in the Human Brain) at Max Planck Institute of Cognitive Neuroscience, Leipzig. 2000 degree Dr. rer. nat., University of Leipzig. 2000 to 2011 Research Associate at University Medical Center Hamburg-Eppendorf, Hamburg (Department of Neurology, then Department of Systems Neuroscience). 2011 appointed Juniorprofessor of Magnetic Resonance Imaging at University of Lübeck, Institute of Medical Engineering; Professor since Nov. 2018.


Publications

2023[ to top ]
  • Ulloa, P., Methot, V., Wottschel, V. and Koch, M. A.: Extra-axonal contribution to double diffusion encoding-based pore size estimates in the corticospinal tract, Magnetic Resonance Materials in Physics, Biology and Medicine, 36(4), 589–612, 2023, DOI: 10.1007/s10334-022-01058-8.
2022[ to top ]
  • Wegner, F., Lüdtke-Buzug, K., Cremers, S., Friedrich, T., Sieren, M. M., Haegele, J., Koch, M. A., Saritas, E. U., Borm, P., Buzug, T. M., Barkhausen, J. and Ahlborg, M.: Bimodal Interventional Instrument Markers for Magnetic Particle Imaging and Magnetic Resonance Imaging---A Proof-of-Concept Study, Nanomaterials, 12(10), 1758, 2022, DOI: 10.3390/nano12101758.
  • Wegner, F., Cremers, S., Lüdtke-Buzug, K., Koch, M. A., Friedrich, T., Grzyska, U., Sieren, M. M., Haegele, J., Borm, P., Buzug, T. M., Barkhausen, J. and Ahlborg, M.: Instrument markers for magnetic particle and magnetic resonance imaging, 2022.
2020[ to top ]
  • Szwargulski, P., Wilmes, M., Javidi, E., Thieben, F., Graeser, M., Koch, M., Grüttner, C., Adam, G., Gerloff, C., Magnus, T., Knopp, T. and Ludewig, P.: Monitoring Intracranial Cerebral Hemorrhage Using Multi-Contrast Real-Time Magnetic Particle Imaging, ACS Nano, 14(10), 13913–13923, 2020, DOI: 10.1021/acsnano.0c06326.
2019[ to top ]
  • Wattenberg, M., Hagenah, J., Schareck, C., Ernst, F. and Koch, M. A.: Head Movement Detection from Radial k-Space Lines using Convolutional Neural Networks -- A Digital Phantom Study, 4859, 2019.
  • Ibbeken, A., Gurumurthy, P., Zell, F., Hagen, C., Koch, M. A. and Buzug, T. M.: MRI flow measurements with a flexible stenosis phantom, Current Directions in Biomedical Engineering, 5(1), 565–568, 2019, DOI: 10.1515/cdbme-2019-0142.
2018[ to top ]
  • Wegner, F., Friedrich, T., Panagiotopoulos, N., Valmaa, S., Goltz, J. P., Vogt, F. M., Koch, M. A., Buzug, T. M., Barkhausen, J. and Haegele, J.: First heating measurements of endovascular stents in magnetic particle imaging, Physics in Medicine and Biology, 63(4), 045005, 2018, DOI: 10.1088%2F1361-6560%2Faaa79c.
  • Koch, M. A., Hagenah, J., Wattenberg, M. and Ernst, F.: Learning motion artefacts in non-Cartesian magnetic resonance imaging, P104, 2018.
  • Schareck, C., Oechtering, T. H., Frydrychowicz, A. and Koch, M. A.: Development of a graphical user interface and cross manufacturer adaptation of a program for determining the pulse wave velocity in the aorta from phase-contrast magnetic resonance images, Current Directions in Biomedical Engineering, 4(1), 477–480, 2018, DOI: 10.1515/cdbme-2018-0114.
2017[ to top ]
  • Methot, V., Ulloa, P. and Koch, M. A.: Pore size estimation from double diffusion encoding, Current Directions in Biomedical Engineering, 30(2), 627–630, 2017, DOI: 10.1515/cdbme-2017-0131.
  • Methot, V., Ulloa, P. and Koch, M. A.: Pore size estimation using the mixing time dependence of a double diffusion encoding experiment: experimental validation on a clinical MR system, 717, 2017.
  • Globisch, A., Melchert, U. H., Erdmann, C. and Koch, M.: Implementation of a correction procedure to decrease the effect of PSF-related signal leakage in 23Na NMRS, S341, 2017, DOI: 10.1515/bmt-2017-5068.
  • Gurumurthy, P., Hagen, C., Ulloa, P., Koch, M. A. and Buzug, T. M.: Computational fluid dynamics simulations and phase contrast-MRI validation of airflow in human pharynx during obstructive sleep apnea, S507, 2017, DOI: 10.1515/bmt-2017-5096.
  • Ulloa, P., Methot, V. and Koch, M. A.: Bias in the apparent exchange rate measurements: insight from numerical simulations, 1085, 2017.
  • Gurumurthy, P., Hagen, C., Ulloa, P., Methot, V., Oechtering, T. H., Frydrychowicz, A., Koch, M. A. and Buzug, T. M.: Time-resolved, 3-dimensional, 3-directionally velocity sensitive phase-contrast MRI for the investigation of flow patterns in a human pharynx phantom during obstructive sleep apnea, S23, 2017, DOI: 10.1007/s10334-017-0632-1.
  • Ulloa, P., Methot, V. and Koch, M. A.: Experimental study of bias in apparent exchange rate measurements, S173-S174, 2017, DOI: 10.1007/s10334-017-0633-0.
  • Ulloa, P., Methot, V. and Koch, M. A.: Experimental validation of a bias in apparent exchange rate measurements, Current Directions in Biomedical Engineering, 3(2), 529–532, 2017, DOI: 10.1515/cdbme-2017-0112.
  • Methot, V., Ulloa, P. and Koch, M. A.: Varying the mixing time of the double diffusion experiment: A better experimental design for pore size estimation, Magnetic Resonance Materials in Physics, Biology and Medicine, 30 (Suppl. 1), S633-S634, 2017, DOI: 10.1007/s10334-017-0635-y.
2016[ to top ]
  • Methot, V. and Koch, M. A.: Pore size distribution estimation using the mixing time dependency of a double diffusion encoding experiment: a proof of concept from Monte Carlo simulated data, S165-S167, 2016, DOI: 10.1007/s10334-016-0569-9.
  • Shemesh, N., Jespersen, S. N., Alexander, D. C., Cohen, Y., Drobnjak, I., Dyrby, T. B., Finsterbusch, J., Koch, M. A., Kuder, T., Laun, F., Lawrenz, M., Lundell, H., Mitra, P. P., Nilsson, M., Özarslan, E., Topgaard, D. and Westin, C.-F.: Conventions and Nomenclature for Double Diffusion Encoding NMR and MRI, Magnetic Resonance in Medicine, 75(1), 82–87, 2016, DOI: 10.1002/mrm.25901.
  • Gurumurthy, P., Ulloa, P., Kluck, C., Buzug, T. M. and Koch, M. A.: Investigation of pharyngeal flow patterns using phase contrast-MRI, S227, 2016, DOI: 10.1515/bmt-2016-5018.
  • Koch, M. A. and Ulloa, P.: Determination of the pore size distribution by double diffusion encoding, 12, 2016, DOI: 10.3389/conf.FPHY.2016.01.00012.
  • Methot, V. and Koch, M. A.: Exploring model limitations for double diffusion encoding MRI, 2016.
  • Schmiedel, M., Möller, A., Koch, M. A. and Mertins, A.: Designing a compact MRI motion phantom, Current Directions in Biomedical Engineering, 2(1), 417–474, 2016, DOI: 10.1515/cdbme-2016-0104.
  • Schmiedel, M., Möller, A., Koch, M. A. and Mertins, A.: Design of a Motion Phantom for Magnetic Resonance Imaging, 251–254, 2016.
  • Ulloa, P., Benedik, A., Landmesser, R. and Koch, M. A.: Water-in-oil Emulsion as a Simple Phantom for Validation of Double Diffusion Encoding MRI Sequences, S48-S49, 2016, DOI: 10.1007/s10334-016-0568-x.
  • Gurumurthy, P., Ulloa, P., Kluck, C., Buzug, T. M. and Koch, M. A.: Study of fluid flow patterns in a human pharynx phantom using phase contrast-MRI, S201-S202, 2016, DOI: 10.1007/s10334-016-0569-9.
  • Bringout, G., Löfberg, J., Ulloa, P., Koch, M. A. and Buzug, T. M.: Designing coils to minimize the maximal induced electrical field amplitude in a patient, 32, 2016.
2015[ to top ]
  • Ulloa, P., Wottschel, V. and Koch, M. A.: Investigating the Extracellular Contribution to the Double-Wave-Vector Diffusion-Weighted Signal, 2786, 2015.
  • Ulloa, P., Wottschel, V. and Koch, A.: Studying the extracellular contribution to the double wave vector diffusion-weighted signal, Current Directions in Biomedical Engineering, 1(1), 240–244, 2015, DOI: 10.1515/cdbme-2015-0060.
  • Ariyamitr, S. and Koch, M. A.: Analyzing the Impact of Different Path Termination Conditions in a Probabilistic Fiber Tracking Algorithm, 2015.
2014[ to top ]
  • Biber, A., Meyer, M. and Koch, M. A.: Visualizing Microscopic Hemorrhages with Susceptibility-Weighted Imaging (SWI) for Forensic Applications, s539-s542, 2014, DOI: 10.1515/bmt-2014-5008.
  • Meyer, M., Biber, A. and Koch, M. A.: Chasing the Zebra. The Quest for the Origin of a Stripe Artifact in Diffusion-Weighted MRI, s535-s538, 2014, DOI: 10.1515/bmt-2014-5008.
  • Timmermeyer, A., Koch, M. A. and Frydrychowicz, A.: Development and Validation of a Tool for Pulse Wave Velocity Measurements in MRI Phase Contrast Data, s543-s546, 2014, DOI: 10.1515/bmt-2014-5008.
  • Ulloa, P., Wottschel, V. and Koch, M. A.: Extracellular Space Contribution to the Double Wave Vector Diffusion-Weighted Signal, s568, 2014, DOI: 10.1515/bmt-2014-5008.
2012[ to top ]
  • Koch, M. A. and Finsterbusch, J.: Double Wave Vector Diffusion Weighting in Wallerian Degeneration, 3564, 2012.
2011[ to top ]
  • Koch, M. A. and Finsterbusch, J.: Towards compartment size estimation in vivo based on double wave vector diffusion weighting, NMR in Biomedicine, 24(10), 1422–1432, 2011, DOI: 10.1002/nbm.1711.
  • Koch, M. A. and Finsterbusch, J.: Concatenated Double Wave Vector Diffusion Weighting Experiments, 3936–3936, 2011.
2010[ to top ]
  • Koch, M. A. and Norris, D. G.: Artifacts and pitfalls in diffusion MR imaging, In: Clinical MR Neuroimaging, Cambridge University Press, Cambridge, 79–85, 2010, ISBN: 9780521515634.
  • Lawrenz, M., Koch, M. A. and Finsterbusch, J.: A tensor model and measures of microscopic anisotropy for double-wave-vector diffusion-weighting experiments with long mixing times, Journal of Magnetic Resonance, 202(1), 43–56, 2010, DOI: 10.1016/j.jmr.2009.09.015.
  • Lawrenz, M., Koch, M. A. and Finsterbusch, J.: Evidence for Microscopic Diffusion Anisotropy in Spinal Cord Tissue Observed with DWV Imaging on a Whole-Body MR System, 4005, 2010.
  • Koch, M. A. and Finsterbusch, J.: In vivo pore size estimation in white matter with double wave vector diffusion weighting, 194, 2010.
2009[ to top ]
  • Lawrenz, M., Koch, M. A. and Finsterbusch, J.: A Tensor Approach for Double Wave Vector Experiments on Microscopic Anisotropy, 3569–3569, 2009.
  • Koch, M. A. and Finsterbusch, J.: Numerical simulation of double-wave vector experiments investigating diffusion in randomly oriented ellipsoidal pores, Magnetic Resonance in Medicine, 62(1), 247–254, 2009, DOI: 10.1002/mrm.21976.
  • Koch, M. A. and Finsterbusch, J.: Trace Weighting in Double Wave Vector Diffusion Experiments in Vivo, 1362–1362, 2009.
2008[ to top ]
  • Finsterbusch, J. and Koch, M. A.: A tensor approach to double wave vector diffusion-weighting experiments on restricted diffusion, Journal of Magnetic Resonance, 195(1), 23–32, 2008, DOI: 10.1016/j.jmr.2008.08.003.
  • Koch, M. A. and Finsterbusch, J.: Compartment size estimation with double wave vector diffusion-weighted imaging, Magnetic Resonance in Medicine, 60(1), 90–101, 2008, DOI: 10.1002/mrm.21514.
  • Klöppel, S., Bäumer, T., Kroeger, J., Koch, M. A., Büchel, C., Münchau, A. and Siebner, H. R.: The cortical motor threshold reflects microstructural properties of cerebral white matter, NeuroImage, 40(4), 1782–1791, 2008, DOI: 10.1016/j.neuroimage.2008.01.019.
  • Koch, M. A. and Finsterbusch, J.: Double Wave Vector Diffusion Weighting in the Human Corticospinal Tract in Vivo, 764, 2008.
2007[ to top ]
  • Hartmann, T., Koch, M. A. and Finsterbusch, J.: Influence on Microscopic Background Gradients on the Diffusion Parameters Observed in a Fiber Model System, 1605, 2007.
2006[ to top ]
  • Wolters, C., Anwander, A., Tricoche, X., Weinstein, D., Koch, M. and MacLeod, R.: Influence of tissue conductivity anisotropy on EEG/MEG field and return current computation in a realistic head model: A simulation and visualization study using high-resolution finite element modeling, NeuroImage, 30(3), 813–826, 2006, DOI: 10.1016/j.neuroimage.2005.10.014.
  • Koch, M. A. and Finsterbusch, J.: Numerical Simulation of Double Wave Vector Diffusion Experiments, 1631–1631, 2006.
  • Finsterbusch, J., Weber-Fahr, W. and Koch, M. A.: Single-Shot 3D Gradient and Stimulated Echo Imaging, 2424, 2006.
  • Finsterbusch, J., Frahm, J. and Koch, M. A.: Gradient and stimulated echo (GRASTE) imaging, Magnetic Resonance in Medicine, 55(2), 455–459, 2006, DOI: 10.1002/mrm.20754.
  • Finsterbusch, J. and Koch, M. A.: Single-Shot STEAM MRI with Cross-Sectional RF Excitations, 2437, 2006.
2005[ to top ]
  • Koch, M. A. and Finsterbusch, J.: Multiple wave vector diffusion experiments on restricted diffusion, 840, 2005.
  • Koch, M. A. and Norris, D. G.: Artifacts and pitfalls in diffusion MR imaging, 99–108, 2005, DOI: 10.1017/cbo9780511544958.008.
2004[ to top ]
  • Sach, M., Winkler, G., Glauche, V., Liepert, J., Heimbach, B., Koch, M. A., Büchel, C. and Weiller, C.: Diffusion tensor MRI of early upper motor neuron involvement in amyotrophic lateral sclerosis, Brain, 127(2), 340–350, 2004, DOI: 10.1093/brain/awh041.
  • Finsterbusch, J. and Koch, M. A.: Single-shot STEAM MRI combined with SENSE, 2251, 2004.
  • Thomalla, G., Glauche, V., Koch, M. A., Beaulieu, C., Weiller, C. and Rother, J.: Motor deficit and early Wallerian degeneration of the pyramidal tract after ischemic stroke: A diffusion tensor imaging study, Stroke, 35(6), E268, 2004.
  • Thomalla, G., Glauche, V., Koch, M. A., Beaulieu, C., Weiller, C. and Röther, J.: Diffusion tensor imaging detects early Wallerian degeneration of the pyramidal tract after ischemic stroke, NeuroImage, 22(4), 1767–1774, 2004, DOI: 10.1016/j.neuroimage.2004.03.041.
  • Koch, M. A. and Finsterbusch, J.: Fibre tracking on q-space data, 1285, 2004.
  • Büchel, C., Raedler, T., Sommer, M., Sach, M., Weiller, C. and Koch, M.: White Matter Asymmetry in the Human Brain: A Diffusion Tensor MRI Study, Cerebral Cortex, 14(9), 945–951, 2004, DOI: 10.1093/cercor/bhh055.
2003[ to top ]
  • Shikata, E., Hamzei, F., Glauche, V., Koch, M., Weiller, C., Binkofski, F. and Büchel, C.: Functional properties and interaction of the anterior and posterior intraparietal areas in humans, European Journal of Neuroscience, 17(5), 1105–1110, 2003, DOI: 10.1046/j.1460-9568.2003.02540.x.
  • Hennig, J., Speck, O., Koch, M. A. and Weiller, C.: Functional magnetic resonance imaging: A review of methodological aspects and clinical applications, Magnetic Resonance Imaging, 18(1), 1–15, 2003, DOI: 10.1002/jmri.10330.
  • Wolters, C. H., Anwander, A., Koch, M. A., Reitzinger, S., Kuhn, M. and Svensén, M.: Influence of Head Tissue Conductivity Anisotropy on Human EEG and MEG using Fast High Resolution Finite Element Modeling, based on a Parallel Algebraic Multigrid Solver, 111–157, 2003.
  • Büchel, C., Glauche, V. and Koch, M. A.: Characterisation of white matter fiber tracts by Catmull-Rom splines, NeuroImage, 19(2, Supplement 1), e1934-e1937, 2003.
2002[ to top ]
  • Koch, M. A., Glauche, V., Finsterbusch, J., Nolte, U. G., Frahm, J., Weiller, C. and Büchel, C.: Distortion-free Diffusion Tensor Imaging of Cranial Nerves and of Inferior Temporal and Orbitofrontal White Matter, NeuroImage, 17(1), 497–506, 2002, DOI: 10.1006/nimg.2002.1171.
  • Koch, M. A., Norris, D. G. and Hund-Georgiadis, M.: An Investigation of Functional and Anatomical Connectivity Using Magnetic Resonance Imaging, NeuroImage, 16(1), 241–250, 2002, DOI: 10.1006/nimg.2001.1052.
  • Sommer, M., Koch, M. A., Glauche, V., Knab, R., Paulus, W., Weiller, C. and Büchel, C.: Disconnection of speech-relevant brain areas in persistent developmental stuttering, The Lancet, 360(9330), 380–383, 2002, DOI: 10.1016/S0140-6736(02)09610-1.
  • Wedegärtner, U., Tchirikov, M., Koch, M., Adam, G. and Schröder, H.: Functional magnetic resonance imaging ({fMRI}) for fetal oxygenation during maternal hypoxia: initial results, RöFo: Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 174(6), 700–703, 2002, DOI: 10.1055/s-2002-32222.
  • Wedegaertner, U., Tchirikov, M., Koch, M., Adam, G. B. and Schroeder, H.: A feasibility study for demonstration of changes in fetal oxygenation during maternal hypoxia by functional magnetic resonance imaging (fMRI), Radiology, 225, 285, 2002.
2001[ to top ]
  • Glauche, V., Sach, M., Koch, M., Winkler, G., Nolte, U., Finsterbusch, J., Frahm, J., Weiller, C. and Büchel, C.: Morphometry on Diffusion Tensor Data, NeuroImage, 13(6:2), 128, 2001, DOI: 10.1016/S1053-8119(01)91471-5.
  • Koch, M. A., Norris, D. G. and Hund-Georgiadis, M.: An Investigation of Functional and Anatomical Connectivity Using Magnetic Resonance Imaging, 1509, 2001.
  • Koch, M., Glauche, V., Finsterbusch, J., Nolte, U., Frahm, J. and Büchel, C.: Estimation of anatomical connectivity from diffusion tensor data, NeuroImage, 13(6:2), 176, 2001, DOI: 10.1016/S1053-8119(01)91519-8.
  • Wolters, C. H., Hartmann, U., Koch, M., Kruggel, F., Burkhardt, S., Basermann, A., Tuch, D. S. and Haueisen, J.: New Methods for Improved and Accelerated FE-Volume Conductor Modelling in EEG/MEG-Source Reconstruction, 1–6, 2001.
2000[ to top ]
  • Koch, M. and Norris, D. G.: An assessment of eddy current sensitivity and correction in single-shot diffusion-weighted imaging, Physics in Medicine and Biology, 45(12), 3821–3832, 2000, DOI: 10.1088/0031-9155/45/12/322.
  • Koch, M.: Measurement of the self-diffusion tensor of water in the human brain, Max Planck Institute of Cognitive Neuroscience, Leipzig, 2000, ISBN: 3980728234.
  • Koch, M. and Norris, D. G.: Distortionless Diffusion Tensor Imaging with UFLARE, 790, 2000.
1998[ to top ]
  • Koch, M., Niendorf, T. and Norris, D. G.: Origins of BOLD Contrast - Diffusion and MTC Weighted Functional Imaging of the Human Brain, 1407–1407, 1998.
1996[ to top ]
  • Fröchtenicht, R., Kaloudis, M., Koch, M. and Huisken, F.: Vibrational spectroscopy of small water complexes embedded in large liquid helium clusters, Journal of Chemical Physics, 105(15), 6128–6140, 1996, DOI: 10.1063/1.472472.
  • Huisken, F., Kaloudis, M., Koch, M. and Werhahn, O.: Experimental study of the O-H ring vibrations of the methanol trimer, Journal of Chemical Physics, 105(19), 8965–8968, 1996, DOI: 10.1063/1.472626.