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• Ulloa, P., Methot, V., Wottschel, V. and Koch, M. A.: Extra-axonal contribution to double diffusion encoding-based pore size estimates in the corticospinal tract, Magnetic Resonance Materials in Physics, Biology and Medicine, in press, DOI: 10.1007/s10334-022-01058-8.
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  @article{QS465-ullo23, abstract = {Purpose: Study the origin of compartment size overestimation in double diffusion encoding MRI (DDE) in vivo experiments in the human corticospinal tract. Here, the extracellular space is hypothesized to be the origin of the DDE signal. By exploiting the DDE sensitivity to pores’ shape, it could be possible to identify the origin of the measured signal. The difference between parallel and perpendicular diffusion gradient orientation can indicate if a compartment is regular or eccentric in shape. As extracellular space can be considered an eccentric compartment, a positive difference would mean a high contribution to the compartment size estimates. Materials and Methods: Computer simulations using MISST and in-vivo experiments in eight healthy volunteers were performed. DDE experiments using a double spin-echo preparation with eight perpendicular directions were measured in vivo. The difference between parallel and perpendicular gradient orientations was analyzed using Wilcoxon signed-rank test and Mann-Whitney-U-test. Results: Simulations and MR experiments showed a statistically significant difference between parallel and perpendicular diffusion gradient orientation ($\alpha=0.05$). Conclusion: The results suggest that the DDE-based size estimate may be considerably influenced by the extra-axonal compartment. However, the experimental results are also consistent with purely intra-axonal contributions in combination with a large fiber orientation dispersion.}, author = {Ulloa, P. and Methot, V. and Wottschel, V. and Koch, M. A.}, journal = {Magnetic Resonance Materials in Physics, Biology and Medicine}, keywords = {DiffusionWeighting IMT KochMartin MR MethotVincent UlloaPatricia WottschelViktor}, title = {Extra-axonal contribution to double diffusion encoding-based pore size estimates in the corticospinal tract}, year = {in press} }
• Pommranz, C., Elmoujarkach, E., Cabello, J., Rafecas, M., Mannheim, J., Santangelo, A., la Fougère, C., Pichler, B. and Schmidt, F.: Simulation Studies and Experimental Model Validation of the Biograph Vision Quadra, Nuklearmedizin - NuclearMedicine, 62(02), V8--, 2023, DOI: 10.1055/s-0043-1766212.
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  @article{noauthororeditor2023simulation, author = {Pommranz, Christian and Elmoujarkach, Ezzat and Cabello, Jorge and Rafecas, Magdalena and Mannheim, Julia and Santangelo, Andrea and la Fougère, Christian and Pichler, Bernd and Schmidt, Fabian}, journal = {Nuklearmedizin - NuclearMedicine}, keywords = {ElmoujarkachEzzat RafecasMagdalena imt}, number = {02}, pages = {V8--}, publisher = {Georg Thieme Verlag}, title = {Simulation Studies and Experimental Model Validation of the Biograph Vision Quadra}, volume = 62, year = 2023 }
• Llosá, G. and Rafecas, M.: Hybrid PET/Compton-camera imaging: an imager for the next generation, The European Physical Journal Plus, 138(3), 214, 2023.
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  @article{llosa2023hybrid, author = {Llos{á}, Gabriela and Rafecas, Magdalena}, journal = {The European Physical Journal Plus}, keywords = {imt mermaid myown nuci nucirangeverification rafecasmagdalena}, number = 3, pages = 214, publisher = {Springer}, title = {Hybrid PET/Compton-camera imaging: an imager for the next generation}, volume = 138, year = 2023 }
• Blancke Soares, Y., Gräser, M., Ackers, J., Bakenecker, A., Friedrich, T., Schumacher, J., Lüdtke Buzug, K., Blümler, P. and Buzug, T.: High gradient nested Halbach system for steering magnetic particles, International Journal on Magnetic Particle Imaging, Vol 8 No 1 Suppl 1 (2022), 2022, DOI: 10.18416/IJMPI.2022.2203012.
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  @article{https://doi.org/10.18416/ijmpi.2022.2203012, author = {Blancke Soares, Yvonne and Gräser, Matthias and Ackers, Justin and Bakenecker, Anna and Friedrich, Thomas and Schumacher, Jonas and Lüdtke Buzug, Kerstin and Blümler, Peter and Buzug, Thorsten}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {ackersjustin bakeneckeranna buzugthorsten friedrichthomas graesermatthias imt luedtkekerstin mpi schumacherjonas soaresyvonne}, pages = {Vol 8 No 1 Suppl 1 (2022)}, publisher = {International Journal on Magnetic Particle Imaging}, title = {High gradient nested Halbach system for steering magnetic particles}, year = 2022 }
• Stelzner, J., Bakenecker, A. C., Behrends, A., Bringout, G., Chen, X., von Gladiss, A., Gräfe, K., Schumacher, J. and Buzug, T. M.: Implementation and imaging with a versatile 180 mm magnetic particle imaging field generator, Journal of Magnetism and Magnetic Materials, 169509, 2022, DOI: 10.1016/j.jmmm.2022.169509.
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  @article{Stelzner_2022, author = {Stelzner, J. and Bakenecker, A.C. and Behrends, A. and Bringout, G. and Chen, X. and von Gladiss, A. and Gräfe, K. and Schumacher, J. and Buzug, T.M.}, journal = {Journal of Magnetism and Magnetic Materials}, keywords = {MAPIT bakeneckeranna behrendsandre bringoutgael buzugthorsten chenxin gladissanselm graefeksenija imt schumacherjonas stelznerjan}, month = {may}, pages = 169509, publisher = {Elsevier {BV}}, title = {Implementation and imaging with a versatile 180 mm magnetic particle imaging field generator}, year = 2022 }
• Neumann, A., Gräfe, K., von Gladiss, A., Ahlborg, M., Behrends, A., Chen, X., Schumacher, J., Soares, Y. B., Friedrich, T., Wei, H., Malhorta, A., Aderhold, E., Bakenecker, A. C., Lüdtke-Buzug, K. and Buzug, T. M.: Recent developments in magnetic particle imaging, Journal of Magnetism and Magnetic Materials, 550, 169037, 2022, DOI: 10.1016/j.jmmm.2022.169037.
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  @article{Neumann_2022, author = {Neumann, Alexander and Gräfe, Ksenija and von Gladiss, Anselm and Ahlborg, Mandy and Behrends, Andr{{é}} and Chen, Xin and Schumacher, Jonas and Soares, Yvonne Blancke and Friedrich, Thomas and Wei, Humin and Malhorta, Ankit and Aderhold, Eric and Bakenecker, Anna C. and Lüdtke-Buzug, Kerstin and Buzug, Thorsten M.}, journal = {Journal of Magnetism and Magnetic Materials}, keywords = {aderholderic ahlborgmandy bakeneckeranna behrendsandre buzugthorsten chenxin friedrichthomas graefeksenija imt luedtkekerstin malhotraankit mpi neumannalexander schumacherjonas soaresyvonne weihuimin}, month = {may}, pages = 169037, publisher = {Elsevier {BV}}, title = {Recent developments in magnetic particle imaging}, volume = 550, year = 2022 }
• Gräser, M., Wegner, F., Schumacher, J., Ahlborg, M., Gräfe, K., Aderhold, E., Soares, Y. B., Lüdtke-Buzug, K., Neumann, A., Stagge, P., Wei, H., Ackers, J. and Buzug, T. M.: Magnetic particle imaging, Die Radiologie, 62(6), 496--503, 2022, DOI: 10.1007/s00117-022-01011-9.
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  @article{Gr_ser_2022, author = {Gräser, Matthias and Wegner, Franz and Schumacher, Jonas and Ahlborg, Mandy and Gräfe, Ksenija and Aderhold, Eric and Soares, Yvonne Blancke and Lüdtke-Buzug, Kerstin and Neumann, Alexander and Stagge, Pascal and Wei, Huimin and Ackers, Justin and Buzug, Thorsten M.}, journal = {Die Radiologie}, keywords = {ackersjustin aderholderic ahlborgmandy buzugthorsten graefeksenija graesermatthias imt luedtkekerstin mpi neumannalexander schumacherjonas soaresyvonne staggepascal weihuimin}, month = {may}, number = 6, pages = {496--503}, publisher = {Springer Science and Business Media {LLC}}, title = {Magnetic particle imaging}, volume = 62, year = 2022 }
• Pennazio, F., Ferrero, V., D'Onghia, G., Garbolino, S., Fiorina, E., Villarreal, O. A. M., Milian, F. M., Monaco, V., Monti, V., Patera, A., Werner, J., Wheadon, R. and Rafecas, M.: Proton therapy monitoring: spatiotemporal emission reconstruction with prompt gamma timing and implementation with PET detectors, Physics in Medicine & Biology, 67(6), 065005, 2022, DOI: 10.1088/1361-6560/ac5765.
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  @article{Pennazio_2022, author = {Pennazio, Francesco and Ferrero, Veronica and D'Onghia, Grazia and Garbolino, Sara and Fiorina, Elisa and Villarreal, Oscar Ariel Marti and Milian, Felix Mas and Monaco, Vincenzo and Monti, Valeria and Patera, Alessandra and Werner, Julius and Wheadon, Richard and Rafecas, Magdalena}, journal = {Physics in Medicine & Biology}, keywords = {NucIRangeVerification RafecasMagdalena WernerJulius imt myown}, month = {mar}, number = 6, pages = {065005}, publisher = {{IOP} Publishing}, title = {Proton therapy monitoring: spatiotemporal emission reconstruction with prompt gamma timing and implementation with {PET} detectors}, volume = 67, year = 2022 }
• Seeger, S., Zvolský, M., Melikov, S., Frerkes, M. and Rafecas, M.: Dedicated Chamber for Multimodal In Vivo Imaging of Adult Zebrafish, Zebrafish, 2022, DOI: 10.1089/zeb.2021.0066.
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  @article{Seeger_2022, author = {Seeger, Steven and Zvolský, Milan and Melikov, Salim and Frerkes, Maja and Rafecas, Magdalena}, journal = {Zebrafish}, keywords = {MERMAID NucI RafecasMagdalena SeegerSteven imt}, month = {mar}, publisher = {Mary Ann Liebert Inc}, title = {Dedicated Chamber for Multimodal In Vivo Imaging of Adult Zebrafish}, year = 2022 }
• Wegner, F., Lüdtke-Buzug, K., Cremers, S., Friedrich, T., Sieren, M. M., Haegele, J., Koch, M. A., Saritas, E. U., Borm, P., Buzug, T. M., Barkhausen, J. and Ahlborg, M.: Bimodal Interventional Instrument Markers for Magnetic Particle Imaging and Magnetic Resonance Imaging---A Proof-of-Concept Study, Nanomaterials, 12(10), 1758, 2022, DOI: 10.3390/nano12101758.
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  @article{Wegner_2022, author = {Wegner, Franz and Lüdtke-Buzug, Kerstin and Cremers, Sjef and Friedrich, Thomas and Sieren, Malte M. and Haegele, Julian and Koch, Martin A. and Saritas, Emine U. and Borm, Paul and Buzug, Thorsten M. and Barkhausen, Joerg and Ahlborg, Mandy}, journal = {Nanomaterials}, keywords = {IMAGINe IMT MPI MR ahlborgmandy buzugthorsten friedrichthomas kochmartin luedtkekerstin}, month = {may}, number = 10, pages = 1758, publisher = {{MDPI}}, title = {Bimodal Interventional Instrument Markers for Magnetic Particle Imaging and Magnetic Resonance Imaging---A Proof-of-Concept Study}, volume = 12, year = 2022 }
• Zvolsky, M. L., Schaar, M., Seeger, S. S., Rakers, S. and Rafecas, M.: Development of a digital zebrafish phantom and its application to dedicated small-fish PET, Physics in Medicine & Biology, 67(17), 175005, 2022, DOI: 10.1088/1361-6560/ac71ee.
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  @article{zvolsky2022development, author = {Zvolsky, Milan Lukas and Schaar, Moritz and Seeger, Steven Sebastian and Rakers, Sebastian and Rafecas, Magdalena}, journal = {Physics in Medicine \& Biology}, keywords = {imt mermaid myown nuci rafecasmagdalena rtf seegersteven}, number = 17, pages = 175005, title = {Development of a digital zebrafish phantom and its application to dedicated small-fish {PET}}, volume = 67, year = 2022 }
• Ahlborg, M., Friedrich, T., Göttsche, T., Scheitenberger, V., Linemann, R., Wattenberg, M., Buessen, A. T., Knopp, T., Szwargulski, P., Kaul, M. G., Salamon, J., Buzug, T. M., Barkhausen, J. and Wegner, F.: First Dedicated Balloon Catheter for Magnetic Particle Imaging, IEEE Transactions on Medical Imaging, 9797737, 2022, DOI: 10.1109/TMI.2022.3183948.
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  @article{9797737, abstract = {Vascular interventions are a promising application of Magnetic Particle Imaging enabling a high spatial and temporal resolution without using ionizing radiation. The possibility to visualize the vessels as well as the devices, especially at the same time using multi-contrast approaches, enables a higher accuracy for diagnosis and treatment of vascular diseases. Different techniques to make devices MPI visible have been introduced so far, such as varnish markings or filling of balloons. However, all approaches include challenges for in <i>vivo</i> applications, such as the stability of the varnishing or the visibility of tracer filled balloons in deflated state. In this contribution, we present for the first time a balloon catheter that is molded from a granulate incorporating nanoparticles and can be visualized sufficiently in MPI. Computed tomography is used to show the homogeneous distribution of particles within the material. Safety measurements confirm that the incorporation of nanoparticles has no negative effect on the balloon. A dynamic experiment is performed to show that the inflation as well as deflation of the balloon can be imaged with MPI.}, author = {Ahlborg, Mandy and Friedrich, Thomas and Göttsche, Thorsten and Scheitenberger, Vincent and Linemann, Reinhard and Wattenberg, Maximilian and Buessen, Anne T. and Knopp, Tobias and Szwargulski, Patryk and Kaul, Michael G. and Salamon, Johannes and Buzug, Thorsten M. and Barkhausen, Jörg and Wegner, Franz}, journal = {IEEE Transactions on Medical Imaging}, keywords = {ahlborgmandy buzugthorsten imt maximilianwattenberg mpi skampi thomasfriedrich}, pages = 9797737, title = {First Dedicated Balloon Catheter for Magnetic Particle Imaging}, year = 2022 }
• Hackelberg, N., Schumacher, J., Graeser, M. and Knopp, T.: A Flexible High-Performance Signal Generation and Digitization Plattform based on Low-Cost Hardware, International Journal on Magnetic Particle Imaging, Vol 8 No 1 Suppl 1 (2022), 2022, DOI: 10.18416/IJMPI.2022.2203063.
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  @article{https://doi.org/10.18416/ijmpi.2022.2203063, author = {Hackelberg, Niklas and Schumacher, Jonas and Graeser, Matthias and Knopp, Tobias}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {graesermatthias imt mpi schumacherjonas}, pages = {Vol 8 No 1 Suppl 1 (2022)}, publisher = {International Journal on Magnetic Particle Imaging}, title = {A Flexible High-Performance Signal Generation and Digitization Plattform based on Low-Cost Hardware}, year = 2022 }
• Elmoujarkach, E., Seeger, S., Schareck, C., De Graaf, L., Barkhausen, J. and Rafecas, M.: Characterization of Using Infused PLA for 3DPrinted Radiation Shielding, Current Directions in Biomedical Engineering, 8(2), 2022, DOI: https://doi.org/10.1515/cdbme-2022-1147.
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  @article{elmoujarkach2022characterization, author = {Elmoujarkach, Ezzat and Seeger, Steven and Schareck, Constantin and De Graaf, Leoni and Barkhausen, Jörg and Rafecas, Magdalena}, journal = {Current Directions in Biomedical Engineering}, keywords = {elmoujarkachezzat imt mermaid nuci rafecasmagdalena rtf seegersteven}, number = 2, title = {Characterization of Using Infused PLA for 3DPrinted Radiation Shielding}, volume = 8, year = 2022 }
• Ibbeken, A., Zell, F., Hagen, C., Grzyska, U., Steffen, A., Frydrychowicz, A. and Buzug, T. M.: Experimental FSI simulation validation of an anthropomorphic upper airway phantom, Transactions on Additive Manufacturing Meets Medicine, 4(1), 674, 2022, DOI: 10.18416/AMMM.2022.2209674.
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  @article{https://doi.org/10.18416/ammm.2022.2209674, author = {Ibbeken, Alina and Zell, Fenja and Hagen, Christina and Grzyska, Ulrike and Steffen, Armin and Frydrychowicz, Alex and Buzug, Thorsten M.}, journal = {Transactions on Additive Manufacturing Meets Medicine}, keywords = {AirflowSimulation HagenChristina IbbekenAlina ZellFenja buzugthorsten imt}, number = 1, pages = 674, publisher = {Transactions on Additive Manufacturing Meets Medicine}, title = {Experimental FSI simulation validation of an anthropomorphic upper airway phantom}, volume = 4, year = 2022 }
• Zell, F., Ibbeken, A., Hagen, C., Steffen, A., Grzyska, U., Frydrychowicz, A. and Buzug, T. M.: Evaluation of the influence of the nasal cavity in flow simulations of the upper airway of a sleep apnea patient, Current Directions in Biomedical Engineering, 8(2), 253-256, 2022, DOI: 10.1515/cdbme-2022-1065.
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  @article{zell2022evaluation, author = {Zell, Fenja and Ibbeken, Alina and Hagen, Christina and Steffen, Armin and Grzyska, Ulrike and Frydrychowicz, Alex and Buzug, Thorsten M}, journal = {Current Directions in Biomedical Engineering}, keywords = {AirflowSimulation HagenChristina IbbekenAlina ZellFenja buzugthorsten imt}, number = 2, pages = {253-256}, title = {Evaluation of the influence of the nasal cavity in flow simulations of the upper airway of a sleep apnea patient}, volume = 8, year = 2022 }
• Ferrero, V., Werner, J., Cerello, P., Fiorina, E., Vignati, A., Pennazio, F. and Rafecas, M.: Estimating the stopping power distribution during proton therapy: A proof of concept, Frontiers in Physics, 2022, DOI: 10.3389/fphy.2022.971767.
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  @article{ferrero2022estimating, abstract = {Objective. We introduce a new treatment verification technique to estimate the primary particle's stopping power from prompt gamma timing measurements in proton therapy. Approach. The starting point is the Spatio-temporal Emission Recostruction technique, which provides the time-depth distribution of the emitted prompt photons with a multiple Prompt-Gamma Timing detector setup based on Lanthanum Bromide crystals. A dedicated formalism based on an analytical approximation of the stopping power is developed to obtain the desired information. Its performance is evaluated in a proof of concept configuration via Monte Carlo simulations of monochromatic proton beams impinging on a homogeneous PMMA phantom. Main Results. Results indicate stopping power estimations as good as 3.8% with respect to NIST values, and range estimations within 0.3 cm (standard deviation), when considering 250 ps FWHM timing resolution. Significance. The current study shows, for the first time, the feasibility of evaluating the stopping power of primary beams with a technique that can be performed in-vivo, opening up new possibilities in the field of treatment verification and therapy optimization.}, author = {Ferrero, Veronica and Werner, Julius and Cerello, Piergiorgio and Fiorina, Elisa and Vignati, Anna and Pennazio, Francesco and Rafecas, Magdalena}, editor = {Vasquez Osorio, Eliana Maria}, journal = {Frontiers in Physics}, keywords = {NucI NucIRangeVerification RafecasMagdalena WernerJulius imt myown}, month = {sep}, publisher = {Frontiers}, title = {Estimating the stopping power distribution during proton therapy: A proof of concept}, type = {article}, year = 2022 }
• Dell, A. C., Wagner, G., Own, J. and Geibel, J. P.: 3D Bioprinting Using Hydrogels: Cell Inks and Tissue Engineering Applications, Pharmaceutics, 14(12), 2596, 2022, DOI: 10.3390/pharmaceutics14122596.
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  @article{Dell_2022, author = {Dell, Annika C. and Wagner, Grayson and Own, Jason and Geibel, John P.}, journal = {Pharmaceutics}, keywords = {DellAnnika IMT IMTE imt myown}, month = {nov}, number = 12, pages = 2596, publisher = {{MDPI} {AG}}, title = {3D Bioprinting Using Hydrogels: Cell Inks and Tissue Engineering Applications}, volume = 14, year = 2022 }
• Ferrero, V., Werner, J., Aglietta, M., Cerello, P., Fiorina, E., Gorgi, A., Vignati, A., Rafecas, M. and Pennazio, F.: The MERLINO project:characterization of LaBr3:Ce detectors for stopping power monitoring in proton therapy, Journal of Instrumentation, 17(11), C11013, 2022, DOI: 10.1088/1748-0221/17/11/C11013.
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  @article{Ferrero_2022, abstract = {The MERLINO project is developing a multi-detector setup with the goal of evaluating the beam stopping power from Prompt-Gamma-Timing measurements in proton therapy. The detectors are based on the cerium-doped lanthanum bromide crystal, LaBr3:Ce, coupled to photo-multiplier tubes. The system characterization is ongoing and the first calibration measurements with two detectors showed 124 ps σ and σ E/E = 3% for the timing and energy resolution, respectively. The measured experimental parameters were then used to carry out a preliminary estimation of the stopping power. Results from the simulation of a 189 MeV proton beam impinging on an homogeneous phantom are presented for the optimisation of the MERLINO detector setup.}, author = {Ferrero, V. and Werner, J. and Aglietta, M. and Cerello, P. and Fiorina, E. and Gorgi, A. and Vignati, A. and Rafecas, M. and Pennazio, F.}, journal = {Journal of Instrumentation}, keywords = {NucI NucIRangeVerification RafecasMagdalena WernerJulius imt}, month = {nov}, number = 11, pages = {C11013}, publisher = {IOP Publishing}, title = {The MERLINO project:characterization of LaBr3:Ce detectors for stopping power monitoring in proton therapy}, volume = 17, year = 2022 }
• Wegner, F., von Gladiss, A., Wei, H., Behrends, A., Grzyska, U., Sieren, M. M., Haegele, J., Graeser, M., Buzug, T. M., Barkhausen, J. and Friedrich, T.: Heating of Large Endovascular Stents and Stent Grafts in Magnetic Particle Imaging-Influence of Measurement Parameters and Isocenter Distance, CardioVascular and Interventional Radiology, 2022, DOI: 10.1007/s00270-022-03324-7.
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  @article{Wegner_2022, author = {Wegner, Franz and von Gladiss, Anselm and Wei, Huimin and Behrends, Andr{{é}} and Grzyska, Ulrike and Sieren, Malte M. and Haegele, Julian and Graeser, Matthias and Buzug, Thorsten M. and Barkhausen, Joerg and Friedrich, Thomas}, journal = {{CardioVascular} and Interventional Radiology}, keywords = {imt imte mpi}, month = {dec}, publisher = {Springer Science and Business Media {LLC}}, title = {Heating of Large Endovascular Stents and Stent Grafts in Magnetic Particle Imaging-Influence of Measurement Parameters and Isocenter Distance}, year = 2022 }
• Banoqitah, E., Elmoujarkach, E., Alnadwi, F., Alhawsawi, A. M. and Alawi, M.: A Simulation Analysis for Thermal Neutron Applications of ABS 3D Printing Filament Doped with Nanoparticles, Arabian Journal for Science and Engineering, 2021, DOI: 10.1007/s13369-021-05482-1.
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  @article{Banoqitah_2021, author = {Banoqitah, Essam and Elmoujarkach, Ezzat and Alnadwi, Fuad and Alhawsawi, Abdulsalam M. and Alawi, Mohammed}, journal = {Arabian Journal for Science and Engineering}, keywords = {ElmoujarkachEzzat imt}, month = {mar}, publisher = {Springer Science and Business Media {LLC}}, title = {A Simulation Analysis for Thermal Neutron Applications of {ABS} 3D Printing Filament Doped with Nanoparticles}, year = 2021 }
• Rusiecka, K., Hetzel, R., Kasper, J., Kozani, M. K., Kohlhase, N., Kolodziej, M., Lalik, R., Magiera, A., Migdal, W., Rafecas, M., Stahl, A., Urbanevych, V., Wong, M. L. and Wro'nska, A.: A systematic study of LYSO:Ce, LuAG:Ce and GAGG:Ce scintillating fibers properties, Journal of Instrumentation, 16(11), P11006, 2021, DOI: 10.1088/1748-0221/16/11/p11006.
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  @article{2021, author = {Rusiecka, K. and Hetzel, R. and Kasper, J. and Kozani, M. Kazemi and Kohlhase, N. and Ko{\l}odziej, M. and Lalik, R. and Magiera, A. and Migda{\l}, W. and Rafecas, M. and Stahl, A. and Urbanevych, V. and Wong, M.L. and Wro{{{\'n}}}ska, A.}, journal = {Journal of Instrumentation}, keywords = {CC Compton KohlhaseNadja NucI NucIRangeVerification RafecasMagdalena imt myown}, month = {nov}, number = 11, pages = {P11006}, publisher = {{IOP} Publishing}, title = {A systematic study of {LYSO}:Ce, {LuAG}:Ce and {GAGG}:Ce scintillating fibers properties}, volume = 16, year = 2021 }
• Thrun, S., Pedrosa, D., Schulze, M., Buzug, T. M. and Stille, M.: Creation of a 3D printed human head phantom, Transactions on Additive Manufacturing Meets Medicine, 3(1), 608, 2021, DOI: 10.18416/AMMM.2021.2109608.
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  @article{thrun2021creation, author = {Thrun, Solveig and Pedrosa, David and Schulze, Maximilian and Buzug, Thorsten M. and Stille, Maik}, journal = {Transactions on Additive Manufacturing Meets Medicine}, keywords = {buzugthorsten ct imt stillemaik}, number = 1, pages = 608, publisher = {Transactions on Additive Manufacturing Meets Medicine}, title = {Creation of a 3D printed human head phantom}, volume = 3, year = 2021 }
• Ibbeken, A., Hagen, C., Zell, F., Steffen, A., Grzyska, U., Frydrychowicz, A. and Buzug, T. M.: Design and construction of a flexible pharyngeal phantom, Transactions on Additive Manufacturing Meets Medicine, 3(1), 499, 2021, DOI: 10.18416/AMMM.2021.2109499.
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  @article{https://doi.org/10.18416/ammm.2021.2109499, author = {Ibbeken, Alina and Hagen, Christina and Zell, Fenja and Steffen, Armin and Grzyska, Ulrike and Frydrychowicz, Alex and Buzug, Thorsten M.}, journal = {Transactions on Additive Manufacturing Meets Medicine}, keywords = {AirflowSimulation HagenChristina IbbekenAlina ZellFenja buzugthorsten imt}, number = 1, pages = 499, publisher = {Transactions on Additive Manufacturing Meets Medicine}, title = {Design and construction of a flexible pharyngeal phantom}, volume = 3, year = 2021 }
• Dell, A., Wegner, F., Aderhold, E., Buzug, T. M. and Friedrich, T.: Stenosis simulation of femoral arteries using an adaptive 3D-printed actuator, Transactions on Additive Manufacturing Meets Medicine, 3(1), 2021, DOI: 10.18416/AMMM.2021.2109576.
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  @article{https://doi.org/10.18416/ammm.2021.2109576, author = {Dell, Annika and Wegner, Franz and Aderhold, Eric and Buzug, Thorsten M. and Friedrich, Thomas}, journal = {Transactions on Additive Manufacturing Meets Medicine}, keywords = {AderholdEric DellAnnika FriedrichThomas buzugthorsten imt imte myown}, number = 1, publisher = {Transactions on Additive Manufacturing Meets Medicine}, title = {Stenosis simulation of femoral arteries using an adaptive 3D-printed actuator}, volume = 3, year = 2021 }
• Wegner, F., von Gladiss, A., Haegele, J., Grzyska, U., Sieren, M. M., Stahlberg, E., Oechtering, T. H., Lüdtke-Buzug, K., Barkhausen, J., Buzug, T. M. and Friedrich, T.: Magnetic Particle Imaging: In vitro Signal Analysis and Lumen Quantification of 21 Endovascular Stents, International Journal of Nanomedicine, 16, 213-221, 2021, DOI: 10.2147/IJN.S284694.
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  @article{wegnerltpgtmagnetic, author = {Wegner, Franz and von Gladiss, Anselm and Haegele, Julian and Grzyska, Ulrike and Sieren, Malte Maria and Stahlberg, Erik and Oechtering, Thekla Helene and Lüdtke-Buzug, Kerstin and Barkhausen, Joerg and Buzug, Thorsten M and Friedrich, Thomas}, journal = {International Journal of Nanomedicine}, keywords = {FriedrichThomas IMAGINe buzugthorsten imt luedtkekerstin mpi myown skampi}, pages = {213-221}, publisher = {Dove Press}, title = {Magnetic Particle Imaging: In vitro Signal Analysis and Lumen Quantification of 21 Endovascular Stents}, type = {website}, volume = 16, year = 2021 }
• Grzyska, U., Friedrich, T., Sieren, M. M., Stahlberg, E., Oechtering, T. H., Ahlborg, M., Buzug, T. M., Frydrychowicz, A., Barkhausen, J., Haegele, J. and Wegner, F.: Heating of an Aortic Stent for Coarctation Treatment During Magnetic Particle Imaging and Magnetic Resonance Imaging---A Comparative In Vitro Study, CardioVascular and Interventional Radiology, 2021, DOI: 10.1007/s00270-021-02795-4.
  [ BibTeX ] [ URL ]
   
  @article{Grzyska2021, abstract = {To evaluate heating of a redilatable stent for the treatment of aortic coarctation in neonates and small children in the new imaging modality magnetic particle imaging and established magnetic resonance imaging.}, author = {Grzyska, Ulrike and Friedrich, Thomas and Sieren, Malte M. and Stahlberg, Erik and Oechtering, Thekla H. and Ahlborg, Mandy and Buzug, Thorsten M. and Frydrychowicz, Alex and Barkhausen, Joerg and Haegele, Julian and Wegner, Franz}, journal = {CardioVascular and Interventional Radiology}, keywords = {ahlborgmandy buzugthorsten friedrichthomas imt luedtkekerstin mpi myown skampi}, month = {mar}, title = {Heating of an Aortic Stent for Coarctation Treatment During Magnetic Particle Imaging and Magnetic Resonance Imaging---A Comparative In Vitro Study}, year = 2021 }
• Bente, K., Bakenecker, A. C., von Gladiss, A., Bachmann, F., Ce̅bers, A., Buzug, T. M. and Faivre, D.: Selective Actuation and Tomographic Imaging of Swarming Magnetite Nanoparticles, ACS Applied Nano Materials, 2021, DOI: 10.1021/acsanm.1c00768.
  [ BibTeX ] [ URL ]
   
  @article{Bente2021, author = {Bente, Klaas and Bakenecker, Anna C. and von Gladiss, Anselm and Bachmann, Felix and Ce̅bers, Andrejs and Buzug, Thorsten M. and Faivre, Damien}, journal = {{ACS} Applied Nano Materials}, keywords = {bakeneckeranna buzugthorsten gladissanselm imt mpi}, publisher = {American Chemical Society ({ACS})}, title = {Selective Actuation and Tomographic Imaging of Swarming Magnetite Nanoparticles}, year = 2021 }
• Bakenecker, A. C., von Gladiss, A., Schwenke, H., Behrends, A., Friedrich, T., Lüdtke-Buzug, K., Neumann, A., Barkhausen, J., Wegner, F. and Buzug, T. M.: Navigation of a magnetic micro-robot through a cerebral aneurysm phantom with magnetic particle imaging, Scientific Reports, 11(1), 2021, DOI: 10.1038/s41598-021-93323-4.
  [ BibTeX ] [ URL ]
   
  @article{bakenecker2021micro-robot, author = {Bakenecker, Anna C. and von Gladiss, Anselm and Schwenke, Hannes and Behrends, André and Friedrich, Thomas and Lüdtke-Buzug, Kerstin and Neumann, Alexander and Barkhausen, Joerg and Wegner, Franz and Buzug, Thorsten M.}, journal = {Scientific Reports}, keywords = {bakeneckeranna behrendsandre buzugthorsten friedrichthomas gladissanselm imt luedtkekerstin mpi neumannalexander}, number = 1, title = {Navigation of a magnetic micro-robot through a cerebral aneurysm phantom with magnetic particle imaging}, volume = 11, year = 2021 }
• Blancke Soares, Y., Lüdtke-Buzug, K., Von Gladiss, A., Debbeler, C., Buzug, T. M. and Gräfe, K.: Further system characterization of the Single-Sided MPI Scanner with two- and three-dimensional measurements, International Journal on Magnetic Particle Imaging, Vol 7 No 2 (2021), 2021, DOI: 10.18416/IJMPI.2021.2109001.
  [ BibTeX ] [ URL ]
   
  @article{https://doi.org/10.18416/ijmpi.2021.2109001, author = {Blancke Soares, Yvonne and Lüdtke-Buzug, Kerstin and Von Gladiss, Anselm and Debbeler, Christina and Buzug, Thorsten M. and Gräfe, Ksenija}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {buzugthorsten debbelerchristina gladissanselm graefeksenija imt luedtkekerstin mpi soaresyvonne}, pages = {Vol 7 No 2 (2021)}, publisher = {International Journal on Magnetic Particle Imaging}, title = {Further system characterization of the Single-Sided MPI Scanner with two- and three-dimensional measurements}, year = 2021 }
• Peñate Medina, T., Kolb, J. P., Hüttmann, G., Huber, R., Peñate Medina, O., Ha, L., Ulloa, P., Larsen, N., Ferrari, A., Rafecas, M., Ellrichmann, M., Pravdivtseva, M. S., Anikeeva, M., Humbert, J., Both, M., Hundt, J. E. and Hövener, J. -B.: Imaging Inflammation --- From Whole Body Imaging to Cellular Resolution, Frontiers in Immunology, 12, 692222, 2021, DOI: 10.3389/fimmu.2021.692222.
  [ BibTeX ] [ URL ]
   
  @article{Pe_ate_Medina_2021, author = {Pe{ñ}ate Medina, Tuula and Kolb, Jan Philip and Hüttmann, Gereon and Huber, Robert and Pe{ñ}ate Medina, Oula and Ha, Linh and Ulloa, Patricia and Larsen, Naomi and Ferrari, Arianna and Rafecas, Magdalena and Ellrichmann, Mark and Pravdivtseva, Mariya S. and Anikeeva, Mariia and Humbert, Jana and Both, Marcus and Hundt, Jennifer E. and Hövener, Jan-Bernd}, editor = {Distler, Oliver}, journal = {Frontiers in Immunology}, keywords = {NucI RafecasMagdalena imaging imt inflammation}, month = {jun}, pages = 692222, publisher = {Frontiers Media {SA}}, title = {Imaging Inflammation --- From Whole Body Imaging to Cellular Resolution}, volume = 12, year = 2021 }
• Sarrut, D., Bala, M., Bardiès, M., Bert, J., Chauvin, M., Chatzipapas, K., Dupont, M., Etxebeste, A., Fanchon, L. M., Jan, S., Kayal, G., Kirov, A. S., Kowalski, P., Krzemien, W., Labour, J., Lenz, M., Loudos, G., Mehadji, B., Ménard, L., Morel, C., Papadimitroulas, P., Rafecas, M., Salvadori, J., Seiter, D., Stockhoff, M., Testa, E., Trigila, C., Pietrzyk, U., Vandenberghe, S., Verdier, M. -A., Visvikis, D., Ziemons, K., Zvolsk'y, M. and Roncali, E.: Advanced Monte Carlo simulations of emission tomography imaging systems with GATE, Physics in Medicine & Biology, 66(10), 10TR03, 2021, DOI: 10.1088/1361-6560/abf276.
  [ BibTeX ] [ URL ]
   
  @article{Sarrut_2021, author = {Sarrut, David and Ba{\l}a, Mateusz and Bardi{{è}}s, Manuel and Bert, Julien and Chauvin, Maxime and Chatzipapas, Konstantinos and Dupont, Mathieu and Etxebeste, Ane and Fanchon, Louise M and Jan, S{{é}}bastien and Kayal, Gunjan and Kirov, Assen S and Kowalski, Pawe{\l} and Krzemien, Wojciech and Labour, Joey and Lenz, Mirjam and Loudos, George and Mehadji, Brahim and M{{é}}nard, Laurent and Morel, Christian and Papadimitroulas, Panagiotis and Rafecas, Magdalena and Salvadori, Julien and Seiter, Daniel and Stockhoff, Mariele and Testa, Etienne and Trigila, Carlotta and Pietrzyk, Uwe and Vandenberghe, Stefaan and Verdier, Marc-Antoine and Visvikis, Dimitris and Ziemons, Karl and Zvolsk{{{\'y}}}, Milan and Roncali, Emilie}, journal = {Physics in Medicine {\&} Biology}, keywords = {MERMAID NucI RafecasMagdalena ZvolskyMilan imt}, month = {may}, number = 10, pages = {10TR03}, publisher = {{IOP} Publishing}, title = {Advanced Monte Carlo simulations of emission tomography imaging systems with {GATE}}, volume = 66, year = 2021 }
• Rodriguez, A. F. R., dos Santos, C. C., Lüdtke-Buzug, K., Bakenecker, A. C., Chaves, Y. O., Mariúba, L. A. M., Brandt, J. ~ao V., Amantea, B. E., de Santana, R. C., Marques, R. F. C., Jafelicci, M. and Morales, M. A.: Evaluation of antiplasmodial activity and cytotoxicity assays of amino acids functionalized magnetite nanoparticles: Hyperthermia and flow cytometry applications, Materials Science and Engineering: C, 125, 112097, 2021, DOI: 10.1016/j.msec.2021.112097.
  [ BibTeX ] [ URL ]
   
  @article{Rodriguez_2021, author = {Rodriguez, Anselmo F.R. and dos Santos, Caio C. and Lüdtke-Buzug, K. and Bakenecker, Anna C. and Chaves, Yury O. and Mari{{ú}}ba, Luis A.M. and Brandt, Jo{\~{a}}o V. and Amantea, Bruno E. and de Santana, Ricardo C. and Marques, Rodrigo F.C. and Jafelicci, Miguel and Morales, Marco A.}, journal = {Materials Science and Engineering: C}, keywords = {buzugthorsten imt luedtkekerstin mpi}, month = {jun}, pages = 112097, publisher = {Elsevier {BV}}, title = {Evaluation of antiplasmodial activity and cytotoxicity assays of amino acids functionalized magnetite nanoparticles: Hyperthermia and flow cytometry applications}, volume = 125, year = 2021 }
• Bakenecker, A. C., Chinchilla, C. and Buzug, T. M.: Actuation of a magnetically coated swimmer in viscous media with a magnetic particle imaging scanner, Current Directions in Biomedical Engineering, 6(3), 2020, DOI: 10.1515/cdbme-2020-3090.
  [ BibTeX ] [ URL ]
   
  @article{CurrentDirections, author = {Bakenecker, Anna C. and Chinchilla, Carlos and Buzug, Thorsten M.}, journal = {Current Directions in Biomedical Engineering}, keywords = {bakeneckeranna buzugthorsten imt mpi}, number = 3, title = {Actuation of a magnetically coated swimmer in viscous media with a magnetic particle imaging scanner}, volume = 6, year = 2020 }
• Neumann, A. and Buzug, T. M.: Simulations of magnetic particles with arbitrary anisotropies, International Journal on Magnetic Particle Imaging, 6(2), Suppl. 1, 2009032, 2020, DOI: 10.18416/IJMPI.2020.2009032.
  [ BibTeX ] [ URL ]
   
  @article{neumann2020simulations, abstract = {To simulate the behavior of realistic magnetic particles in magnetic particle imaging it is not enough to perform simulations assuming only a uniaxial magnetic anisotropy energy due to the complex coupling between the magnetic and the mechanic degrees of freedom of the particle in multidimensional excitation fields. Most particles can only be approximated of having uniaxial magnetic anisotropy energy. As such, this work will discuss the shortcoming of currently used models focusing on only uniaxial anisotropy and show how a theoretical model must be defined to allow for arbitrary anisotropy energies. First simulation results showing the differences between different anisotropy energies will be presented at the workshop.}, author = {Neumann, Alexander and Buzug, Thorsten M.}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {buzugthorsten imt mpi neumannalexander samba}, number = 2, pages = {Suppl. 1, 2009032}, title = {Simulations of magnetic particles with arbitrary anisotropies}, volume = 6, year = 2020 }
• Ibbeken, A., Hagen, C., Zell, F., Steffen, A., Grzyska, U., Frydrychowicz, A. and Buzug, T. M.: Determination of the critical closing pressure for a 3D printed collapsible model of an idealized upper airway geometry, Transactions on Additive Manufacturing Meets Medicine, 2(1), 2020, DOI: 10.18416/AMMM.2020.2009025.
  [ BibTeX ] [ URL ]
   
  @article{https://doi.org/10.18416/ammm.2020.2009025, author = {Ibbeken, Alina and Hagen, Christina and Zell, Fenja and Steffen, Armin and Grzyska, Ulrike and Frydrychowicz, Alex and Buzug, Thorsten M.}, journal = {Transactions on Additive Manufacturing Meets Medicine}, keywords = {AirflowSimulation HagenChristina IbbekenAlina ZellFenja buzugthorsten imt}, number = 1, publisher = {Transactions on Additive Manufacturing Meets Medicine}, title = {Determination of the critical closing pressure for a 3D printed collapsible model of an idealized upper airway geometry}, volume = 2, year = 2020 }
• Grzyska, U., Ibbeken, A., Zell, F., Hagen, C., Steffen, A., Abrams, N., Kooijman, H., Buzug, T., Barkhausen, J. and Frydrychowicz, A.: Analyse der isotropen, Compressed SENSE-beschleunigten 3D T1 TSE zur Atemwegsanalyse bei Patienten mit obstruktivem Schlafapnoesyndrom, RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 192(S 01), WISS-5, 2020, DOI: 10.1055/s-0040-1703358.
  [ BibTeX ]
   
  @article{grzyska2020analyse, author = {Grzyska, U and Ibbeken, A and Zell, F and Hagen, C and Steffen, A and Abrams, N and Kooijman, H and Buzug, T and Barkhausen, J and Frydrychowicz, A}, journal = {RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren}, keywords = {AirflowSimulation HagenChristina IbbekenAlina ZellFenja buzugthorsten imt}, number = {S 01}, pages = {WISS-5}, title = {Analyse der isotropen, Compressed SENSE-beschleunigten 3D T1 TSE zur Atemwegsanalyse bei Patienten mit obstruktivem Schlafapnoesyndrom}, volume = 192, year = 2020 }
• Medina, O. P., Tower, R. J., Medina, T. P., Ashkenani, F., Appold, L., Bötcher, M., Huber, L., Will, O., Ling, Q., Hauser, C., Rohwedder, A., Heneweer, C., Peschke, E., Hövener, J. -B., Lüdtke-Buzug, K., Boretius, S., Mentlein, R., Kairemo, K., Glüer, C. C., Sebens, S. and Kalthoff, H.: Multimodal Targeted Nanoparticle-Based Delivery System for Pancreatic Tumor Imaging in Cellular and Animal Models, Current Pharmaceutical Design, 26, 2020, DOI: 10.2174/1381612826666200717084846.
  [ BibTeX ] [ URL ]
   
  @article{Medina_2020, author = {Medina, Oula Penate and Tower, Robert J. and Medina, Tuula Penate and Ashkenani, Fatma and Appold, Lia and Bötcher, Marcus and Huber, Lukas and Will, Olga and Ling, Qi and Hauser, Charlotte and Rohwedder, Arndt and Heneweer, Carola and Peschke, Eva and Hövener, Jan-Bernd and Lüdtke-Buzug, Kerstin and Boretius, Susann and Mentlein, Rolf and Kairemo, Kalevi and Glüer, Claus C. and Sebens, Susanne and Kalthoff, Holger}, journal = {Current Pharmaceutical Design}, keywords = {buzugthorsten imt luedtkekerstin mpi}, month = {jul}, publisher = {Bentham Science Publishers Ltd.}, title = {Multimodal Targeted Nanoparticle-Based Delivery System for Pancreatic Tumor Imaging in Cellular and Animal Models}, volume = 26, year = 2020 }
• Kohlhase, N., Wegener, T., Schaar, M., Bolke, A., Etxebeste, A., Sarrut, D. and Rafecas, M.: Capability of MLEM and OE to Detect Range Shifts with a Compton Camera in Particle Therapy, IEEE Transactions on Radiation and Plasma Medical Sciences, 4(2), 233-242, 2020, DOI: 10.1109/TRPMS.2019.2937675.
  [ BibTeX ] [ URL ]
   
  @article{8815866, abstract = {To identify range deviations by using Compton cameras (CC), tomographic image reconstruction of CC data is needed. Within this context, image reconstruction is usually performed using Maximum Likelihood Expectation Maximization (MLEM), and more recently, the Origin Ensemble (OE) algorithm. In this work, we investigate how MLEM and OE affect the precision and accuracy of estimated range deviations. In particular, we focus on the effects of data selection, statistical fluctuations, and artifact reduction. The use of external information of the beam path through a hodoscope was also explored. Additionally, two methods to calculate range deviations were tested. To this aim, realistic proton beams were simulated using GATE and data from single spots as well as from 7 contiguous spots of an energy layer were reconstructed. MLEM and OE reacted differently to the poor data statistics. In general, both algorithms were able to detect range shifts for single spots, particularly when multiple coincidences were also considered. Selection of events corresponding to the most relevant energy peaks decreased the identification performance due to the lower statistics. When data from several contiguous spots were jointly reconstructed, the accuracy of the results degraded significantly, and non-zero shifts were assigned when no shifts had occurred. The limited size of the cameras and the subsequent restriction in the orientation and aperture of detected cones, as well as in the number of detected events are major challenges. Future efforts should be devoted to noise regularization and compensation for data truncation.}, author = {{Kohlhase}, N. and {Wegener}, T. and {Schaar}, M. and {Bolke}, A. and {Etxebeste}, A. and {Sarrut}, D. and {Rafecas}, M.}, journal = {IEEE Transactions on Radiation and Plasma Medical Sciences}, keywords = {BolkeAndreas KohlhaseNadja NucI NucIRangeVerification RafecasMagdalena SchaarMoritz imt}, month = {March}, number = 2, pages = {233-242}, title = {Capability of MLEM and OE to Detect Range Shifts with a Compton Camera in Particle Therapy}, volume = 4, year = 2020 }
• Stelzner, J., Gräfe, K. and Buzug, T. M.: First images obtained with a rabbit-sized Magnetic Particle Imaging scanner, International Journal on Magnetic Particle Imaging, Vol 6 No 2 Suppl. 1 (2020), 2020, DOI: https://doi.org/10.18416/IJMPI.2020.2009033.
  [ BibTeX ] [ URL ]
   
  @article{noauthororeditor, author = {Stelzner, Jan and Gräfe, Ksenija and Buzug, Thorsten M.}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {buzugthorsten graefeksenija imt mapit mpi stelznerjan}, pages = {Vol 6 No 2 Suppl. 1 (2020)}, title = {First images obtained with a rabbit-sized Magnetic Particle Imaging scanner}, year = 2020 }
• Wegner, F., Friedrich, T., von Gladiss, A., Grzyska, U., Sieren, M. M., Lüdtke-Buzug, K., Frydrychowicz, A., Buzug, T. M., Barkhausen, J. and Haegele, J.: Magnetic Particle Imaging: Artifact-Free Metallic Stent Lumen Imaging in a Phantom Study, CardioVascular and Interventional Radiology, 43(2), 331--338, 2020, DOI: 10.1007/s00270-019-02347-x.
  [ BibTeX ] [ URL ]
   
  @article{Wegner2020, abstract = {To illustrate the potential of magnetic particle imaging (MPI) for stent lumen imaging in comparison with clinical computed tomography (CT) and magnetic resonance imaging (MRI).}, author = {Wegner, Franz and Friedrich, Thomas and von Gladiss, Anselm and Grzyska, Ulrike and Sieren, Malte M. and L{ü}dtke-Buzug, Kerstin and Frydrychowicz, Alex and Buzug, Thorsten M. and Barkhausen, J{ö}rg and Haegele, Julian}, journal = {CardioVascular and Interventional Radiology}, keywords = {FriedrichThomas GladissAnselm IMAGINe SKAMPI buzugthorsten imt luedtkekerstin}, month = {feb}, number = 2, pages = {331--338}, title = {Magnetic Particle Imaging: Artifact-Free Metallic Stent Lumen Imaging in a Phantom Study}, volume = 43, year = 2020 }
• Abrams, N., Steffen, A., Grzyska, U., Frydrychowicz, A., Barkhausen, J., Hagen, C., Ibbeken, A., Zell, F. and Buzug, T. M.: Die intraindividuelle Nacht-zu-Nacht-Variabilität in der peripher-arteriellen Tonometrie – Wie verändert sich der Rückenlage- und REM-Anteil?, Laryngorhinootologie, 99(S 02), 2020, DOI: 10.1055/s-0040-1711979.
  [ BibTeX ]
   
  @article{abrams2020intraindividuelle, author = {Abrams, N and Steffen, A and Grzyska, U and Frydrychowicz, A and Barkhausen, Jörg and Hagen, C and Ibbeken, A and Zell, F and Buzug, Thorsten M.}, journal = {Laryngorhinootologie}, keywords = {AirflowSimulation HagenChristina IbbekenAlina ZellFenja buzugthorsten imt}, number = {S 02}, title = {Die intraindividuelle Nacht-zu-Nacht-Variabilität in der peripher-arteriellen Tonometrie – Wie verändert sich der Rückenlage- und REM-Anteil?}, volume = 99, year = 2020 }
• Bakenecker, A. C., Schumacher, J., Blümler, P., Gräfe, K., Ahlborg, M. and Buzug, T. M.: A concept for a magnetic particle imaging scanner with Halbach arrays, Physics in Medicine and Biology, 65(19), 2020, DOI: 10.1088/1361-6560/ab7e7e.
  [ BibTeX ] [ URL ]
   
  @article{bakenecker2020PMB, author = {Bakenecker, Anna C. and Schumacher, Jonas and Blümler, Peter and Gräfe, Ksenija and Ahlborg, Mandy and Buzug, Thorsten M.}, journal = {Physics in Medicine and Biology}, keywords = {ahlborgmandy bakeneckeranna buzugthorsten graefeksenija imt mpi schumacherjonas}, number = 19, title = {A concept for a magnetic particle imaging scanner with Halbach arrays}, volume = 65, year = 2020 }
• Gräfe, K. and Buzug, T. M.: Simulation study to minimize the single-sided FFP MPI scanner, International Journal on Magnetic Particle Imaging, Vol 6 No 2 Suppl. 1 (2020), 2020, DOI: https://doi.org/10.18416/IJMPI.2020.2009047.
  [ BibTeX ] [ URL ]
   
  @article{noauthororeditor, author = {Gräfe, Ksenija and Buzug, Thorsten M.}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {buzugthorsten graefeksenija imt mpi singlesided}, pages = {Vol 6 No 2 Suppl. 1 (2020)}, title = {Simulation study to minimize the single-sided FFP MPI scanner}, year = 2020 }
• Von Gladiss, A., Graeser, M., Cordes, A., Bakenecker, A. C., Behrends, A., Chen, X. and Buzug, T. M.: Investigating Spatial Resolution, Field Sequences and Image Reconstruction Strategies using Hybrid Phantoms in MPI, International Journal on Magnetic Particle Imaging, 6(1), 2020, DOI: 10.18416/IJMPI.2020.2003004.
  [ BibTeX ] [ URL ]
   
  @article{vonGladiss2020IJMPI, author = {Von Gladiss, Anselm and Graeser, Matthias and Cordes, Aileen and Bakenecker, Anna C. and Behrends, André and Chen, Xin and Buzug, Thorsten M.}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {bakeneckeranna behrendsandre buzugthorsten chenxin cordesaileen gladissanselm graesermatthias imt mpi}, number = 1, publisher = {International Journal on Magnetic Particle Imaging}, title = {Investigating Spatial Resolution, Field Sequences and Image Reconstruction Strategies using Hybrid Phantoms in MPI}, volume = 6, year = 2020 }
• Bakenecker, A. C., von Gladiss, A., Friedrich, T. and Buzug, T. M.: 3D-Printing with Incorporated Iron Particles for Magnetic Actuation and MPI, International Journal on Magnetic Particle Imaging, 6(1), 2020, DOI: 10.18416/ijmpi.2020.2003001.
  [ BibTeX ] [ URL ]
   
  @article{bakenecker2020IJMPI, author = {Bakenecker, Anna C. and von Gladiss, Anselm and Friedrich, Thomas and Buzug, Thorsten M.}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {bakeneckeranna buzugthorsten friedrichthomas gladissanselm imt mpi}, number = 1, title = {3D-Printing with Incorporated Iron Particles for Magnetic Actuation and MPI}, volume = 6, year = 2020 }
• Blancke Soares, Y., Gräfe, K., Lüdtke-Buzug, K. and Buzug, T. M.: Investigation of the spatial resolution and penetration depth of a single-sided MPI device in three-dimensional imaging, International Journal on Magnetic Particle Imaging, Vol 6 No 2 Suppl. 1 (2020), 2020, DOI: https://doi.org/10.18416/IJMPI.2020.2009053.
  [ BibTeX ] [ URL ]
   
  @article{noauthororeditor, author = {Blancke Soares, Yvonne and Gräfe, Ksenija and Lüdtke-Buzug, Kerstin and Buzug, Thorsten M.}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {buzugthorsten graefeksenija imt luedtkekerstin mpi singlesided soaresyvonne}, pages = {Vol 6 No 2 Suppl. 1 (2020)}, title = {Investigation of the spatial resolution and penetration depth of a single-sided MPI device in three-dimensional imaging}, year = 2020 }
• Chen, X., Behrends, A., Malhotra, A., Neumann, A. and Buzug, T. M.: Temperature-dependent spectrum measurement using a magnetic particle spectrometer, International Journal on Magnetic Particle Imaging, 6(2), Suppl 1, 2020, DOI: https://doi.org/10.18416/IJMPI.2020.2009034.
  [ BibTeX ]
   
  @article{chen2020temperaturedependent, author = {Chen, Xin and Behrends, André and Malhotra, Ankit and Neumann, Alexander and Buzug, Thorsten M.}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {behrendsandre buzugthorsten chenxin imt mpi mps neumannalexander samba}, number = 2, pages = {Suppl 1}, title = {Temperature-dependent spectrum measurement using a magnetic particle spectrometer}, volume = 6, year = 2020 }
• von Gladiss, A., Graeser, M., Behrends, A., Chen, X. and Buzug, T. M.: Efficient hybrid 3D system calibration for magnetic particle imaging systems using a dedicated device, Scientific Reports, 10(1), 2020, DOI: 10.1038/s41598-020-75122-5.
  [ BibTeX ] [ URL ]
   
  @article{VonGladiss2020a, author = {von Gladiss, Anselm and Graeser, Matthias and Behrends, Andr{{é}} and Chen, Xin and Buzug, Thorsten M.}, journal = {Scientific Reports}, keywords = {behrendsandre buzugthorsten chenxin gladissanselm graesermatthias imt mpi mps}, month = {oct}, number = 1, publisher = {Springer Science and Business Media {LLC}}, title = {Efficient hybrid 3D system calibration for magnetic particle imaging systems using a dedicated device}, volume = 10, year = 2020 }
• Klemme, T., Buzug, T. M. and Neumann, A.: Exploring Parameters of Magnetic Particles in 1D Field Excitation, International Journal on Magnetic Particle Imaging, 6(2), 2004001, 2020, DOI: 10.18416/IJMPI.2020.2004001.
  [ BibTeX ] [ URL ]
   
  @article{klemme2020, abstract = {This work explores how different parameters, e.g. magnetic anisotropy and core radius, influence the signal/spectrum of magnetic particles in a one-dimensional excitation field. Simulations are performed using a model considering both the mechanical and magnetization dynamics of the particle. The performed simulations show an increase of amplitude at higher harmonics for anisotropy constants within a certain range. This increase is also observed for different magnetic radii. The obtained knowledge can help to improve the performance of magnetic particles in magnetic particle imaging.}, author = {Klemme, Tobias and Buzug, Thorsten M. and Neumann, Alexander}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {buzugthorsten imt klemmetobias mpi neumannalexander samba}, number = 2, pages = 2004001, title = {Exploring Parameters of Magnetic Particles in 1D Field Excitation}, volume = 6, year = 2020 }
• Bakenecker, A. C., Schumacher, J., Blümler, P., Gräfe, K., Ahlborg, M. and Buzug, T. M.: A concept for an MPI scanner with Halbach arrays, International Journal on Magnetic Particle Imaging, Vol 6 No 2 Suppl. 1 (2020), 2020, DOI: 10.18416/IJMPI.2020.2009008.
  [ BibTeX ] [ URL ]
   
  @article{bakenecker2020IWMPI2, author = {Bakenecker, Anna C. and Schumacher, Jonas and Blümler, Peter and Gräfe, Ksenija and Ahlborg, Mandy and Buzug, Thorsten M.}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {AhlborgMandy BakeneckerAnna BuzugThorsten GraefeKsenija SchumacherJonas imt mpi}, pages = {Vol 6 No 2 Suppl. 1 (2020)}, publisher = {International Journal on Magnetic Particle Imaging}, title = {A concept for an MPI scanner with Halbach arrays}, year = 2020 }
• Szwargulski, P., Wilmes, M., Javidi, E., Thieben, F., Graeser, M., Koch, M., Grüttner, C., Adam, G., Gerloff, C., Magnus, T., Knopp, T. and Ludewig, P.: Monitoring Intracranial Cerebral Hemorrhage Using Multi-Contrast Real-Time Magnetic Particle Imaging, ACS Nano, 14(10), 13913--13923, 2020, DOI: 10.1021/acsnano.0c06326.
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  @article{MP014-szwa20, author = {Szwargulski, Patryk and Wilmes, Maximilian and Javidi, Ehsan and Thieben, Florian and Graeser, Matthias and Koch, Martin and Grüttner, Cordula and Adam, Gerhard and Gerloff, Christian and Magnus, Tim and Knopp, Tobias and Ludewig, Peter}, journal = {ACS Nano}, keywords = {IMT KochMartin MR}, number = 10, pages = {13913--13923}, title = {Monitoring Intracranial Cerebral Hemorrhage Using Multi-Contrast Real-Time Magnetic Particle Imaging}, volume = 14, year = 2020 }
• Ferrero, V., Pennazio, F., Cerello, P., Fiorina, E., Garbolino, S., Monaco, V., Wheadon, R. and Rafecas, M.: Evaluation of in-beam PET treatment verification in proton therapy with different reconstruction methods, IEEE Transactions on Radiation and Plasma Medical Sciences, 2019, DOI: 10.1109/TRPMS.2019.2942713.
  [ BibTeX ] [ URL ]
   
  @article{8845670, abstract = {In-beam PET monitoring can provide early treatment assessment in proton therapy. However, open ring configurations and low positron emitter production yields degrade image quality, hampering the assessment accuracy. To achieve the highest precision for range monitoring, it is compulsory to mitigate image noise and compensate for data truncation. The goal of this work is to study the performance of state-of-the-art algorithms for in-beam PET image reconstruction, by evaluating the impact of the system response model and assessing the accuracy of range measurements. The approaches investigated here were Maximum-A-Posteriori algorithms combined with Total-Variation and Median-Root Priors. Maximum-Likelihood-Expectation-Maximization was used as reference. To compute the system matrix, different models were compared: a precise Monte Carlo model, and Single-Ray Tracing with and without Gaussian blurring in image space. The proposed methods were tested on simulations of Spread-Out-Bragg-Peaks delivered on phantoms. The I3PET scanner geometry was used as a case study. After image post-processing, the explored methods delivered similar results. Our work demonstrates the feasibility and reliability of using a simple and fast reconstruction method to perform range evaluations, given the correct image post-processing.}, author = {{Ferrero}, V. and {Pennazio}, F. and {Cerello}, P. and {Fiorina}, E. and {Garbolino}, S. and {Monaco}, V. and {Wheadon}, R. and {Rafecas}, M.}, journal = {IEEE Transactions on Radiation and Plasma Medical Sciences}, keywords = {NucI NucIRangeVerification RafecasMagdalena imt myown}, title = {Evaluation of in-beam PET treatment verification in proton therapy with different reconstruction methods}, year = 2019 }
• Ehrhardt, J., Ahlborg, M., Uzunova, H., Buzug, T. M. and Handels, H.: Temporal Polyrigid Registration for Patch-based MPI Reconstruction of Moving Objects, International Journal on Magnetic Particle Imaging, 5(1), 1908001, 2019, DOI: 10.18416/ijmpi.2019.1908001.
  [ BibTeX ] [ URL ]
   
  @article{ehrhardt2019temporal, author = {Ehrhardt, Jan and Ahlborg, Mandy and Uzunova, Hristina and Buzug, Thorsten M. and Handels, Heinz}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {MPITheo ahlborgmandy buzugthorsten imt}, number = 1, pages = 1908001, title = {Temporal Polyrigid Registration for Patch-based MPI Reconstruction of Moving Objects}, volume = 5, year = 2019 }
• Wattenberg, M., Stille, M., Klein, P. and Buzug, T. M.: 2D Contour Reconstruction for Industrial Computed Tomography using Crease Cluster, e-Journal of Nondestructive Testing, 2019.
  [ BibTeX ]
   
  @article{wattenberg2019contour, author = {Wattenberg, Maximilian and Stille, Maik and Klein, Philipp and Buzug, Thorsten M.}, editor = {Diederichs, Rolf}, journal = {e-Journal of Nondestructive Testing}, keywords = {BuzugThorsten CT WattenbergMaximilian imt stillemaik}, title = {2{D} Contour Reconstruction for Industrial Computed Tomography using Crease Cluster}, year = 2019 }
• Malhotra, A., von Gladiss, A., Behrends, A., Friedrich, T., Neumann, A., Buzug, T. M. and Lüdtke-Buzug, K.: Tracking the Growth of Superparamagnetic Nanoparticles with an In-Situ Magnetic Particle Spectrometer (INSPECT), Scientific Reports, 9(10538), 2019, DOI: https://doi.org/10.1038/s41598-019-46882-6.
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  @article{malhotra2019tracking, abstract = {Magnetic Particle Spectroscopy (MPS) is a measurement technique to determine the magnetic properties of superparamagnetic iron oxide nanoparticles (SPIONs) in an oscillating magnetic field as applied in Magnetic Particle Imaging (MPI). State of the art MPS devices are solely capable of measuring the magnetization response of the SPIONs to an oscillatory magnetic excitation retrospectively, i.e. after the synthesis process. In this contribution, a novel in-situ magnetic particle spectrometer (INSPECT) is presented, which can be used to monitor the entire synthesis process from particle genesis via growth to the stable colloidal suspension of the nanoparticles in real time. The device is suitable for the use in a biochemistry environment. It has a chamber size of 72 mm such that a 100 ml reaction flask can be used for synthesis. For an alkaline-based precipitation, the change of magnetic properties of SPIONs during the nucleation and growth phase of the synthesis is demonstrated. The device is able to record the changes in the amplitude and phase spectra, and, in turn, the hysteresis. Hence, it is a powerful tool for an in-depth understanding of the nanoparticle formation dynamics during the synthesis process.}, author = {Malhotra, Ankit and von Gladiss, Anselm and Behrends, André and Friedrich, Thomas and Neumann, Alexander and Buzug, Thorsten M. and Lüdtke-Buzug, Kerstin}, journal = {Scientific Reports}, keywords = {BCE BehrendsAndre FMT FriedrichThomas GladissAnselm MPI MPS MalhotraAnkit NeumannAlexander SAMBA SKAMPI SPIO imt luedtkekerstin}, month = {jul}, number = 10538, title = {Tracking the Growth of Superparamagnetic Nanoparticles with an In-Situ Magnetic Particle Spectrometer (INSPECT)}, volume = 9, year = 2019 }
• Ibbeken, A., Gurumurthy, P., Zell, F., Hagen, C., Koch, M. A. and Buzug, T. M.: MRI flow measurements with a flexible stenosis phantom, Current Directions in Biomedical Engineering, 5(1), 565--568, 2019, DOI: 10.1515/cdbme-2019-0142.
  [ BibTeX ] [ URL ]
   
  @article{PC065-ibbe19, author = {Ibbeken, Alina and Gurumurthy, Pragathi and Zell, Fenja and Hagen, Christina and Koch, Martin A. and Buzug, Thorsten M.}, booktitle = {Annual Conference Deutsche Gesellschaft für Biomedizinische Technik, Frankfurt/Main, Sept. 25--26, 2019}, journal = {Current Directions in Biomedical Engineering}, keywords = {AirFlowSimulation BuzugThorsten GurumurthyPragathi HagenChristina ICM IMT IbbekenAlina KochMartin MR ZellFenja}, number = 1, pages = {565--568}, title = {{MRI} flow measurements with a flexible stenosis phantom}, volume = 5, year = 2019 }
• Rehberg, I., Richter, R., Hartung, S., Lucht, N., Hankiewicz, B. and Friedrich, T.: Measuring magnetic moments of polydisperse ferrofluids utilizing the inverse Langevin function, Physical Review B, 100(13), 134425, 2019, DOI: 10.1103/PhysRevB.100.134425.
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  @article{PhysRevB.100.134425, abstract = {The dipole strength of magnetic particles in a suspension is obtained by a graphical rectification of the magnetization curves based on the inverse Langevin function. The method yields the arithmetic and the harmonic mean of the particle distribution. It has an advantage compared to the fitting of magnetization curves to some appropriate mathematical model: It does not rely on assuming a particular distribution function of the particles.}, author = {Rehberg, Ingo and Richter, Reinhard and Hartung, Stefan and Lucht, Niklas and Hankiewicz, Birgit and Friedrich, Thomas}, journal = {Physical Review B}, keywords = {FriedrichThomas MPI MPS SKAMPI SPIO imt myown}, month = {oct}, number = 13, pages = 134425, publisher = {American Physical Society}, title = {Measuring magnetic moments of polydisperse ferrofluids utilizing the inverse Langevin function}, volume = 100, year = 2019 }
• Friedrich, T., Wattenberg, M., Tüshaus, L., Wünsch, L. and Buzug, T. M.: Presurgical practice of supracondylar domosteotomie of cubitus varus deformity on 3D printed humerus, Transactions on Additive Manufacturing Meets Medicine, 1(2), Vol 1 (2019): Trans. AMMM-, 2019, DOI: 10.18416/AMMM.2019.1909S01T06.
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  @article{https://doi.org/10.18416/ammm.2019.1909s01t06, abstract = {Complicated fractures of bones can be difficult to treat, and there is a high probability that further operative corrections need to be carried out. In the present work, we present a case study, where a model of the humerus of a six-year-old male patient was 3D-printed from a segmented CT-dataset for a preoperative optimization of the geometric parameters of a supracondylar domosteotomy. The experimental simulation of the treatment has proven very useful to the physician, and the patient has been treated successfully.}, author = {Friedrich, Thomas and Wattenberg, Maximilian and Tüshaus, Ludger and Wünsch, Lutz and Buzug, Thorsten M.}, journal = {Transactions on Additive Manufacturing Meets Medicine}, keywords = {FMT SKAMPI buzugthorsten friedrichthomas imt myown wattenbergmaximilian}, number = 2, pages = {Vol 1 (2019): Trans. AMMM-}, publisher = {Infinite Science Publishing}, title = {Presurgical practice of supracondylar domosteotomie of cubitus varus deformity on 3D printed humerus}, volume = 1, year = 2019 }
• Zell, F., Mannheim, J., Grehn, M. and Rafecas, M.: 3D-printed standardized phantoms for small animal PET and MRI: a comparison study, Transactions on Additive Manufacturing Meets Medicine, Vol 1 (2019): Trans. AMMM, 2019, DOI: 10.18416/AMMM.2019.1909S03P07.
  [ BibTeX ] [ URL ]
   
  @article{https://doi.org/10.18416/ammm.2019.1909s03p07, author = {Zell, Fenja and Mannheim, Julia and Grehn, Melanie and Rafecas, Magdalena}, journal = {Transactions on Additive Manufacturing Meets Medicine}, keywords = {NucI RafecasMagdalena ZellFenja imt}, pages = {Vol 1 (2019): Trans. AMMM}, publisher = {Transactions on Additive Manufacturing Meets Medicine}, title = {3D-printed standardized phantoms for small animal PET and MRI: a comparison study}, year = 2019 }
• Bakenecker, A. C., von Gladiss, A., Friedrich, T., Heinen, U., Lehr, H., Lüdtke-Buzug, K. and Buzug, T. M.: Actuation and Visualization of a Magnetically Coated Swimmer with Magnetic Particle Imaging, Journal of Magnetism and Magnetic Materials, 2019, DOI: 10.1016/j.jmmm.2018.10.056.
  [ BibTeX ]
   
  @article{Bakenecker2018, author = {Bakenecker, Anna C. and von Gladiss, Anselm and Friedrich, Thomas and Heinen, Ulrich and Lehr, Heinrich and Lüdtke-Buzug, Kerstin and Buzug, Thorsten M.}, journal = {Journal of Magnetism and Magnetic Materials}, keywords = {MPI bakeneckeranna buzugthorsten friedrichthomas gladissanselm imt luedtkekerstin}, month = {mar}, publisher = {Elsevier {BV}}, title = {Actuation and Visualization of a Magnetically Coated Swimmer with Magnetic Particle Imaging}, year = 2019 }
• Bakenecker, A. C., Ahlborg, M., Debbeler, C., Kaethner, C., Buzug, T. M. and Lüdtke-Buzug, K.: Magnetic particle imaging in vascular medicine, Innovative Surgical Sciences, 3, 179, 2018, DOI: 10.1515/iss-2018-2026.
  [ BibTeX ] [ URL ]
   
  @article{bakenecker2018magnetic, author = {Bakenecker, Anna C. and Ahlborg, Mandy and Debbeler, Christina and Kaethner, Christian and Buzug, Thorsten M. and Lüdtke-Buzug, Kerstin}, booktitle = {Innovative Surgical Sciences}, keywords = {AhlborgMandy BakeneckerAnna BuzugThorsten DebbelerChristina KaethnerChristian LuedtkeKerstin MPI imt}, pages = 179, title = {Magnetic particle imaging in vascular medicine}, volume = 3, year = 2018 }
• Wegner, F., Friedrich, T., Panagiotopoulos, N., Valmaa, S., Goltz, J. P., Vogt, F. M., Koch, M. A., Buzug, T. M., Barkhausen, J. and Haegele, J.: First heating measurements of endovascular stents in magnetic particle imaging, Physics in Medicine and Biology, 63(4), 045005, 2018, DOI: 10.1088%2F1361-6560%2Faaa79c.
  [ BibTeX ] [ URL ]
   
  @article{Wegner_2018, author = {Wegner, Franz and Friedrich, Thomas and Panagiotopoulos, Nikolaos and Valmaa, Sarah and Goltz, Jan P and Vogt, Florian M and Koch, Martin A and Buzug, Thorsten M and Barkhausen, Joerg and Haegele, Julian}, journal = {Physics in Medicine and Biology}, keywords = {BuzugThorsten FriedrichThomas IMAGINe IMT KochMartin MPI MR SAMBA SKAMPI}, month = {feb}, number = 4, pages = {045005}, publisher = {IOP Publishing}, title = {First heating measurements of endovascular stents in magnetic particle imaging}, volume = 63, year = 2018 }
• Erb, W., Weinmann, A., Ahlborg, M., Brandt, C., Bringout, G., Buzug, T. M., Frikel, J., Kaethner, C., Knopp, T., März, T., Möddel, M., Storath, M. and Weber, A.: Mathematical analysis of the 1D model and reconstruction schemes for magnetic particle imaging, Inverse Problems, 34(5), 055012, 2018, DOI: 10.1088/1361-6420/aab8d1.
  [ BibTeX ]
   
  @article{Erb_2018, author = {Erb, W and Weinmann, A and Ahlborg, M and Brandt, C and Bringout, G and Buzug, T M and Frikel, J and Kaethner, C and Knopp, T and März, T and Möddel, M and Storath, M and Weber, A}, journal = {Inverse Problems}, keywords = {MPITheo ahlborgmandy buzugthorsten imt}, number = 5, pages = {055012}, title = {Mathematical analysis of the 1D model and reconstruction schemes for magnetic particle imaging}, volume = 34, year = 2018 }
• Heinrich, M. P., Stille, M. and Buzug, T. M.: Residual U-Net Convolutional Neural Network Architecture for Low-Dose CT Denoising, Current Directions in Biomedical Engineering, 4(1), 297--300, 2018, DOI: 10.1515/cdbme-2018-0072.
  [ BibTeX ] [ URL ]
   
  @article{Heinrich_2018, author = {Heinrich, Mattias P. and Stille, Maik and Buzug, Thorsten M.}, journal = {Current Directions in Biomedical Engineering}, keywords = {BuzugThorsten CT IMT StilleMaik}, month = {sep}, number = 1, pages = {297--300}, publisher = {Walter de Gruyter {GmbH}}, title = {Residual U-Net Convolutional Neural Network Architecture for Low-Dose {CT} Denoising}, volume = 4, year = 2018 }
• Ferrero, V., Cerello, P., Fiorina, E., Monaco, V., Rafecas, M., Wheadon, R. and Pennazio, F.: Innovation in online hadrontherapy monitoring: An in-beam PET and prompt-gamma-timing combined device, Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2018, DOI: 10.1016/j.nima.2018.08.065.
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  @article{ferrero2018innovation, author = {Ferrero, V. and Cerello, P. and Fiorina, E. and Monaco, V. and Rafecas, M. and Wheadon, R. and Pennazio, F.}, journal = {Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment}, keywords = {NucI NucIRangeVerification RafecasMagdalena imt}, title = {Innovation in online hadrontherapy monitoring: An in-beam PET and prompt-gamma-timing combined device}, year = 2018 }
• Wegner, F., Buzug, T. M. and Barkhausen, J.: Take a Deep Breath - Monitoring of Inhaled Nanoparticles with Magnetic Particle Imaging, Theranostics, 8(13), 3691--3692, 2018, DOI: 10.7150/thno.27454.
  [ BibTeX ] [ URL ]
   
  @article{Wegner_2018, author = {Wegner, Franz and Buzug, Thorsten M. and Barkhausen, Joerg}, journal = {Theranostics}, keywords = {buzugthorsten imt mpi}, number = 13, pages = {3691--3692}, publisher = {Ivyspring International Publisher}, title = {Take a Deep Breath - Monitoring of Inhaled Nanoparticles with Magnetic Particle Imaging}, volume = 8, year = 2018 }
• Chen, X., Graeser, M., Behrends, A., von Gladiss, A. and Buzug, T. M.: First Measurement and SNR Results of a 3D Magnetic Particle Spectrometer, International Journal on Magnetic Particle Imaging, 4(1), 2018, DOI: 10.18416/IJMPI.2018.1810001.
  [ BibTeX ]
   
  @article{chen2018first, author = {Chen, Xin and Graeser, Matthias and Behrends, André and von Gladiss, Anselm and Buzug, Thorsten M.}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {BehrendsAndre ChenXin GladissAnselm GraeserMatthias MPI SAMBA buzugthorsten imt mps}, number = 1, title = {First Measurement and SNR Results of a 3D Magnetic Particle Spectrometer}, volume = 4, year = 2018 }
• Schareck, C., Oechtering, T. H., Frydrychowicz, A. and Koch, M. A.: Development of a graphical user interface and cross manufacturer adaptation of a program for determining the pulse wave velocity in the aorta from phase-contrast magnetic resonance images, Current Directions in Biomedical Engineering, 4(1), 477--480, 2018, DOI: 10.1515/cdbme-2018-0114.
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  @article{PC061-scha18, author = {Schareck, Constantin and Oechtering, Thekla H. and Frydrychowicz, Alex and Koch, Martin A.}, journal = {Current Directions in Biomedical Engineering}, keywords = {IMT KochMartin MR}, number = 1, pages = {477--480}, title = {Development of a graphical user interface and cross manufacturer adaptation of a program for determining the pulse wave velocity in the aorta from phase-contrast magnetic resonance images}, volume = 4, year = 2018 }
• Weber, M., Beuke, J., von Gladiss, A., Gräfe, K., Vogel, P., Behr, V. C. and Buzug, T. M.: Novel Field Geometry Using Two Halbach Cylinders for FFL-MPI, International Journal on Magnetic Particle Imaging, 4(1), 2018, DOI: 10.18416/IJMPI.2018.1811004.
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  @article{weber20182016novel, abstract = {Magnetic Particle Imaging (MPI) offers several methods for encoding magnetic materials in three-dimensions. The complexity of the imaging device in MPI using a field free line (FFL) is the biggest challenge in realizing such devices. This is especially the case for systems featuring large bores, high gradients or high temporal resolution. In this work, we suggest a novel Halbach cylinder based field generator that is able to generate an FFL with a gradient of 5 T/m. By rotating the Halbach array, FFL projections can be acquired. Furthermore, just one static drive field coil is needed for two-dimensional imaging. The presented concept could combine high gradient strength and high temporal resolution with minimum space requirements for FFL-MPI imaging in the future. Int. J. Mag. Part. Imag. 4(2), 2018, Article ID: 1811004, DOI: 10.18416/IJMPI.2018.1811004}, author = {Weber, Matthias and Beuke, Jonas and von Gladiss, Anselm and Gräfe, Ksenija and Vogel, Patrick and Behr, Volker C. and Buzug, Thorsten M.}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {IMT LUMEN beukejonas buzugthorsten gladissanselm graefeksenija schumacherjonas webermatthias}, number = 1, title = {Novel Field Geometry Using Two Halbach Cylinders for FFL-MPI}, type = {Text.Serial.Journal}, volume = 4, year = 2018 }
• Ziemann, C., Stille, M., Cremers, F., Buzug, T. M. and Rades, D.: Improvement of dose calculation in radiation therapy due to metal artifact correction using the augmented likelihood image reconstruction, Journal of Applied Clinical Medical Physics, 19(3), 227--233, 2018, DOI: 10.1002/acm2.12325.
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  @article{Ziemann_2018, author = {Ziemann, Christian and Stille, Maik and Cremers, Florian and Buzug, Thorsten M. and Rades, Dirk}, journal = {Journal of Applied Clinical Medical Physics}, keywords = {MetalArtefactReduction buzugthorsten ct imt stillemaik}, month = {apr}, number = 3, pages = {227--233}, publisher = {Wiley}, title = {Improvement of dose calculation in radiation therapy due to metal artifact correction using the augmented likelihood image reconstruction}, volume = 19, year = 2018 }
• Ziemann, C., Stille, M., Cremers, F., Rades, D. and Buzug, T. M.: The effects of metal artifact reduction on the retrieval of attenuation values, Journal of applied clinical medical physics, 18(1), 243--250, 2017, DOI: 10.1002/acm2.12002.
  [ BibTeX ]
   
  @article{ziemann2017effects, author = {Ziemann, Christian and Stille, Maik and Cremers, Florian and Rades, Dirk and Buzug, Thorsten M}, journal = {Journal of applied clinical medical physics}, keywords = {BuzugThorsten CT IMT MetalArtefactReduction StilleMaik}, number = 1, pages = {243--250}, title = {The effects of metal artifact reduction on the retrieval of attenuation values}, volume = 18, year = 2017 }
• von Gladiss, A., Graeser, M., Szwargulski, P., Knopp, T. and Buzug, T. M.: Hybrid System Calibration for Multidimensional Magnetic Particle Imaging, Physics in Medicine and Biology, 62(9), 3392-3406, 2017, DOI: 10.1088/1361-6560/aa5340.
  [ BibTeX ] [ URL ]
   
  @article{vongladiss2017hybrid, author = {von Gladiss, Anselm and Graeser, Matthias and Szwargulski, Patryk and Knopp, Tobias and Buzug, Thorsten M.}, journal = {Physics in Medicine and Biology}, keywords = {BuzugThorsten GladissAnselm GraeserMatthias MPI MPITheo MPS imt}, number = 9, pages = {3392-3406}, title = {Hybrid System Calibration for Multidimensional Magnetic Particle Imaging}, volume = 62, year = 2017 }
• Graeser, M., von Gladiss, A., Weber, M. and Buzug, T. M.: Two dimensional magnetic particle spectrometry, Physics in Medicine and Biology, 62(9), 3378-3391, 2017, DOI: 10.1088/1361-6560/aa5bcd.
  [ BibTeX ] [ URL ]
   
  @article{graeser2017dimensional, author = {Graeser, Matthias and von Gladiss, Anselm and Weber, Matthias and Buzug, Thorsten M.}, journal = {Physics in Medicine and Biology}, keywords = {BuzugThorsten GladissAnselm GraeserMatthias MPI MPS WeberMatthias imt}, number = 9, pages = {3378-3391}, title = {Two dimensional magnetic particle spectrometry}, volume = 62, year = 2017 }
• Stelzner, J., Graeser, M., Bakenecker, A., von Gladiss, A., Bringout, G. and Buzug, T. M.: Measurements Inside a Rabbit Sized FFL-MPI Device Using a Gradiometric Receive Coil, International Journal on Magnetic Particle Imaging, 3(1), 2017, DOI: 10.18416/IJMPI.2017.1703012.
  [ BibTeX ] [ URL ]
   
  @article{stelzner2017measurements, author = {Stelzner, Jan and Graeser, Matthias and Bakenecker, Anna and von Gladiss, Anselm and Bringout, Gael and Buzug, Thorsten M.}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {BakeneckerAnna BringoutGael BuzugThorsten GladissAnselm GraeserMatthias MAPIT MPI StelznerJan imt}, number = 1, publisher = {Infinite Science Publishing}, title = {Measurements Inside a Rabbit Sized FFL-MPI Device Using a Gradiometric Receive Coil}, volume = 3, year = 2017 }
• Kaethner, C., Cordes, A., Hänsch, A. and Buzug, T. M.: Artifact Analysis for Axially Elongated Lissajous Trajectories in Magnetic Particle Imaging, International Journal on Magnetic Particle Imaging, 3(1), 1703001, 2017, DOI: 10.18416/ijmpi.2017.1703001.
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  @article{kaethner2017artifact, author = {Kaethner, Christian and Cordes, Aileen and H{ä}nsch, Annika and Buzug, Thorsten M.}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {BuzugThorsten CordesAileen KaethnerChristian imt}, number = 1, pages = 1703001, publisher = {Infinite Science Publishing}, title = {Artifact Analysis for Axially Elongated Lissajous Trajectories in Magnetic Particle Imaging}, volume = 3, year = 2017 }
• Methot, V., Ulloa, P. and Koch, M. A.: Pore size estimation from double diffusion encoding, Current Directions in Biomedical Engineering, 30(2), 627--630, 2017, DOI: 10.1515/cdbme-2017-0131.
  [ BibTeX ] [ URL ]
   
  @article{QS269-meth17, author = {Methot, V. and Ulloa, P. and Koch, M. A.}, journal = {Current Directions in Biomedical Engineering}, keywords = {DiffusionWeighting IMT KochMartin MR MethotVincent UlloaPatricia}, note = {Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung, Dresden, Sept. 10--13, 2017}, number = 2, pages = {627--630}, title = {Pore size estimation from double diffusion encoding}, volume = 30, year = 2017 }
• Stelzner, J. and Buzug, T. M.: Magnetic-Field Measurement and Simulation of a Field-Free Line Magnetic-Particle Scanner, Current Directions in Biomedical Engineering, 3(2), 837 -- 840, 2017, DOI: https://doi.org/10.1515/cdbme-2017-0191.
  [ BibTeX ]
   
  @article{stelznerinpressmagneticfield, author = {Stelzner, Jan and Buzug, Thorsten M.}, journal = {Current Directions in Biomedical Engineering}, keywords = {BMT BuzugThorsten IMT MPI StelznerJan}, month = {oct}, note = {Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung, Dresden, Sept. 10--13, 2017}, number = 2, pages = {837 -- 840}, title = {Magnetic-Field Measurement and Simulation of a Field-Free Line Magnetic-Particle Scanner}, volume = 3, year = 2017 }
• Methot, V., Ulloa, P. and Koch, M. A.: Varying the mixing time of the double diffusion experiment: A better experimental design for pore size estimation, Magnetic Resonance Materials in Physics, Biology and Medicine, 30 (Suppl. 1), S633-S634, 2017, DOI: 10.1007/s10334-017-0635-y.
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  @article{QS296-meth17, author = {Methot, V. and Ulloa, P. and Koch, M. A.}, booktitle = {European Society for Magnetic Resonance in Medicine and Biology, 34th Annual Scientific Meeting, Barcelona, October 19--21, 2017}, journal = {Magnetic Resonance Materials in Physics, Biology and Medicine}, keywords = {DiffusionWeighting IMT KochMartin MR MethotVincent UlloaPatricia myown}, note = {contribution no. 674}, pages = {S633-S634}, title = {Varying the mixing time of the double diffusion experiment: {A} better experimental design for pore size estimation}, volume = {30 (Suppl. 1)}, year = 2017 }
• Ulloa, P., Methot, V. and Koch, M. A.: Experimental validation of a bias in apparent exchange rate measurements, Current Directions in Biomedical Engineering, 3(2), 529--532, 2017, DOI: 10.1515/cdbme-2017-0112.
  [ BibTeX ] [ URL ]
   
  @article{QS268-ullo17, author = {Ulloa, P. and Methot, V. and Koch, M. A.}, journal = {Current Directions in Biomedical Engineering}, keywords = {DiffusionWeighting IMT KochMartin MR MethotVincent UlloaPatricia}, note = {Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung, Dresden, Sept. 10--13, 2017}, number = 2, pages = {529--532}, title = {Experimental validation of a bias in apparent exchange rate measurements}, volume = 3, year = 2017 }
• Maass, M., Ahlborg, M., Bakenecker, A., Katzberg, F., Phan, H., Buzug, T. M. and Mertins, A.: A Trajectory Study for Obtaining MPI System Matrices in a Compressed-Sensing Framework, International Journal on Magnetic Particle Imaging, 3(2), 2017, DOI: 10.18416/ijmpi.2017.1706005.
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  @article{maass2017trajectory, author = {Maass, Marco and Ahlborg, Mandy and Bakenecker, Anna and Katzberg, Fabrice and Phan, Huy and Buzug, Thorsten M. and Mertins, Alfred}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {AhlborgMandy BakeneckerAnna BuzugThorsten MPI imt}, number = 2, title = {A Trajectory Study for Obtaining MPI System Matrices in a Compressed-Sensing Framework}, volume = 3, year = 2017 }
• Graeser, M., von Gladiss, A., Friedrich, T. and Buzug, T. M.: SNR and Discretization Enhancement for System Matrix Determination by Decreasing the Gradient in Magnetic Particle Imaging, International Journal on Magnetic Particle Imaging, 3(1), 2017, DOI: 10.18416/IJMPI.2017.1703019.
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  @article{graeser2017discretization, author = {Graeser, Matthias and von Gladiss, Anselm and Friedrich, Thomas and Buzug, Thorsten M.}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {BuzugThorsten FriedrichThomas GladissAnselm GraeserMatthias MPI imt}, number = 1, publisher = {Infinite Science Publishing}, title = {SNR and Discretization Enhancement for System Matrix Determination by Decreasing the Gradient in Magnetic Particle Imaging}, volume = 3, year = 2017 }
• Bakenecker, A., Friedrich, T., von Gladiss, A., Graeser, M., Stelzner, J. and Buzug, T. M.: Experimental Validation of the Selection Field of a Rabbit-Sized FFL Scanner, International Journal on Magnetic Particle Imaging, 3(1), 2017, DOI: 10.18416/IJMPI.2017.1703013.
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  @article{bakenecker2017experimental, author = {Bakenecker, Anna and Friedrich, Thomas and von Gladiss, Anselm and Graeser, Matthias and Stelzner, Jan and Buzug, Thorsten M.}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {BakeneckerAnna BuzugThorsten FriedrichThomas GladissAnselm GraeserMatthias MPI StelznerJan imt mapit}, number = 1, publisher = {Infinite Science Publishing}, title = {Experimental Validation of the Selection Field of a Rabbit-Sized FFL Scanner}, volume = 3, year = 2017 }
• Jacobi, C., Friedrich, T. and Lüdtke-Buzug, K.: Synthesis and Characterisation of Superparamagnetic Polylactic acid based Polymers, International Journal on Magnetic Particle Imaging, 3(2), 1710001, 2017, DOI: 10.18416/ijmpi.2017.1710001.
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  @article{https://doi.org/10.18416/ijmpi.2017.1710001, author = {Jacobi, Caren and Friedrich, Thomas and Lüdtke-Buzug, Kerstin}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {BCE FriedrichThomas IMT LuedtkeKerstin MPI SAMBA SKAMPI myown}, number = 2, pages = 1710001, publisher = {Infinite Science Publishing}, title = {Synthesis and Characterisation of Superparamagnetic Polylactic acid based Polymers}, volume = 3, year = 2017 }
• Hagen, C., Gurumurthy, P. and Buzug, T. M.: Effects of replacing the nasal cavity with a simple pipe like structure in CFD simulations of the airflow within the upper airways of OSA patients with patient individual flow rates, Current Directions in Biomedical Engineering, 3(2), 795--798, 2017, DOI: 10.1515/cdbme-2017-0168.
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  @article{noauthororeditor2017effects, author = {Hagen, Christina and Gurumurthy, Pragathi and Buzug, Thorsten M.}, journal = {Current Directions in Biomedical Engineering}, keywords = {AirflowSimulation BuzugThorsten GurumurthyPragathi HagenChristina ICM IMT KluckChristina MR}, number = 2, pages = {795--798}, title = {Effects of replacing the nasal cavity with a simple pipe like structure in CFD simulations of the airflow within the upper airways of OSA patients with patient individual flow rates}, volume = 3, year = 2017 }
• Graeser, M., Knopp, T., Szwargulski, P., Friedrich, T., von Gladiss, A., Kaul, M., Krishnan, K. M., Ittrich, H., Adam, G. and Buzug, T. M.: Towards Picogram Detection of Superparamagnetic Iron-Oxide Particles Using a Gradiometric Receive Coil, Scientific Reports, 7(6872), 2017, DOI: 10.1038/s41598-017-06992-5.
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  @article{graeser2017towards, abstract = {Superparamagnetic iron-oxide nanoparticles can be used in medical applications like vascular or targeted imaging. Magnetic particle imaging (MPI) is a promising tomographic imaging technique that allows visualizing the 3D nanoparticle distribution concentration in a non-invasive manner. The two main strengths of MPI are high temporal resolution and high sensitivity. While the first has been proven in the assessment of dynamic processes like cardiac imaging, it is unknown how far the detection limit of MPI can be lowered. Within this work, we will present a highly sensitive gradiometric receive-coil unit combined with a noise-matching network tailored for the imaging of mice. The setup is capable of detecting 5 ng of iron in-vitro with an acquisition time of 2.14 sec. In terms of iron concentration we are able to detect 156 μg/L marking the lowest value that has been reported for an MPI scanner so far. In-vivo MPI mouse images of a 512 ng bolus and a 21.5 ms acquisition time allow for capturing the flow of an intravenously injected tracer through the heart of a mouse. Since it has been rather difficult to compare detection limits across MPI publications we propose guidelines to improve the comparability of future MPI studies.}, author = {Graeser, Matthias and Knopp, Tobias and Szwargulski, Patryk and Friedrich, Thomas and von Gladiss, Anselm and Kaul, Michael and Krishnan, Kannan M. and Ittrich, Harald and Adam, Gerhard and Buzug, Thorsten M.}, journal = {Scientific Reports}, keywords = {buzugthorsten friedrichthomas gladissanselm graesermatthias imt mpi}, number = 6872, title = {Towards Picogram Detection of Superparamagnetic Iron-Oxide Particles Using a Gradiometric Receive Coil}, volume = 7, year = 2017 }
• Gräfe, K., von Gladiß, A., Bringout, G., Ahlborg, M. and Buzug, T. M.: 2D Images Recorded With a Single-Sided Magnetic Particle Imaging Scanner, IEEE Transactions on Medical Imaging, 35(4), 1056-1065, 2016, DOI: 10.1109/TMI.2015.2507187.
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  @article{Graefe2016b, abstract = {Magnetic Particle Imaging is a new medical imaging modality, which detects superparamagnetic iron oxide nanoparticles. The particles are excited by magnetic fields. Most scanners have a tube-like measurement field and therefore, both the field of view and the object size are limited. A single-sided scanner has the advantage that the object is not limited in size, only the penetration depth is limited. A single-sided scanner prototype for 1D imaging has been presented in 2009. Simulations have been published for a 2D single-sided scanner and first 1D measurements have been carried out. In this paper, the first 2D single-sided scanner prototype is presented and the first calibration-based reconstruction results of measured 2D phantoms are shown. The field free point is moved on a Lissajous trajectory inside a 30 x 30 mm2 area. Images of phantoms with a maximal distance of 10 mm perpendicular to the scanner surface have been reconstructed. Different cylindrically shaped holes of phantoms have been filled with 6.28 &#x03BC;l undiluted Resovist. After the measurement and image reconstruction of the phantoms, particle volumes could be distinguished with a distance of 2 mm and 6 mm in vertical and horizontal direction, respectively.}, author = {Gräfe, K. and von Gladiß, A. and Bringout, G. and Ahlborg, M. and Buzug, T.M.}, journal = {IEEE Transactions on Medical Imaging}, keywords = {AhlborgMandy BringoutGael BuzugThorsten GladissAnselm GraefeKsenija IMT SingleSided}, number = 4, pages = {1056-1065}, title = {2D Images Recorded With a Single-Sided Magnetic Particle Imaging Scanner}, volume = 35, year = 2016 }
• Weber, A., Werner, F., Weizenecker, J., Buzug, T. M. and Knopp, T.: Artifact free reconstruction with the system matrix approach by overscanning the field-free-point trajectory in magnetic particle imaging, Physics in Medicine and Biology, 61(2), 475, 2016.
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  @article{0031-9155-61-2-475, abstract = {Magnetic particle imaging is a tracer-based imaging method that utilizes the non-linear magnetization response of iron-oxide for determining their spatial distribution. The method is based on a sampling scheme where a sensitive spot is moved along a trajectory that captured a predefined field-of-view (FOV). However, particles outside the FOV also contribute to the measurement signal due to their rotation and the non-sharpness of the sensitive spot. In the present work we investigate artifacts that are induced by particles not covered by the FOV and show that the artifacts can be mitigated by using a system matrix that covers not only the region of interest but also a certain area around the FOV. The findings are especially relevant when using a multi-patch acquisition scheme where the boundaries of neighboring patches have to be handled.}, author = {Weber, A. and Werner, F. and Weizenecker, J. and Buzug, T. M. and Knopp, T.}, journal = {Physics in Medicine and Biology}, keywords = {buzugthorsten imt}, number = 2, pages = 475, title = {Artifact free reconstruction with the system matrix approach by overscanning the field-free-point trajectory in magnetic particle imaging}, volume = 61, year = 2016 }
• Stille, M., Kleine, M., Hagele, J., Barkhausen, J. and Buzug, T. M.: Augmented Likelihood Image Reconstruction, IEEE Transactions on Medical Imaging, 35(1), 158-173, 2016, DOI: 10.1109/TMI.2015.2459764.
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  @article{7164320, abstract = {The presence of high-density objects remains an open problem in medical CT imaging. Data of projections passing through objects of high density, such as metal implants, are dominated by noise and are highly affected by beam hardening and scatter. Reconstructed images become less diagnostically conclusive because of pronounced artifacts that manifest as dark and bright streaks. A new reconstruction algorithm is proposed with the aim to reduce these artifacts by incorporating information about shape and known attenuation coefficients of a metal implant. Image reconstruction is considered as a variational optimization problem. The afore-mentioned prior knowledge is introduced in terms of equality constraints. An augmented Lagrangian approach is adapted in order to minimize the associated log-likelihood function for transmission CT. During iterations, temporally appearing artifacts are reduced with a bilateral filter and new projection values are calculated, which are used later on for the reconstruction. A detailed evaluation in cooperation with radiologists is performed on software and hardware phantoms, as well as on clinically relevant patient data of subjects with various metal implants. Results show that the proposed reconstruction algorithm is able to outperform contemporary metal artifact reduction methods such as normalized metal artifact reduction.}, author = {Stille, M. and Kleine, M. and Hagele, J. and Barkhausen, J. and Buzug, T.M.}, journal = {IEEE Transactions on Medical Imaging}, keywords = {BuzugThorsten CT IMT MetalArtefactReduction StilleMaik}, month = {jan}, number = 1, pages = {158-173}, title = {Augmented Likelihood Image Reconstruction}, volume = 35, year = 2016 }
• Rackebrandt, K. and Gehring, H.: Detection of the venous oxygen saturation in an oxygenation and perfusion model, Biomedical Physics & Engineering Express, 2(1), 015013, 2016.
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  @article{rackebrandt2016detection, abstract = {The oxygenation, perfusion and metabolism of the brain—segmented in both hemispheres—can be estimated from the oxygenation and hemoglobin levels of the venous blood in the cerebral efferent vessels. We present a phantom based model to simulate the anatomical target region which was connected to hemodynamic perfusion circuit to provide different oxygenation plateaus inside of the simulated target vessel. A developed triple-wavelength (770, 808 and 850 nm) multi-distance near-infrared spectroscopy sensor (6 photodiodes (PD 1–6 ), linearly arranged, separated 6 mm each) was equipped to detect these different saturation levels. The saturation could be triggered to three consecutively passed plateaus (PL 1 = 55 ± 3%; PL 2 = 100 ± 0.3%; PL 3 = 55 ± 3%) for all 90 experiments (30 measurements per wavelength (3 d; 10 d −1 )) while keeping the amount of total hemoglobin (tHb) and the other physiological blood parameters at constant levels (tHb = 11.8 ± 0.2 g dl −1 , blood temperature = 35.5 ± 0.5 °C, carbon dioxide partial pressure (pCO 2 ) = 44 ± 6 mmHg, Glucose = 99 ± 8 mg dl −1 and pH 7.35 ± 0.04). The saturation plateaus inside of the target vessel could be detected reproducibly with the presented setup.}, author = {Rackebrandt, K. and Gehring, H.}, journal = {Biomedical Physics & Engineering Express}, keywords = {RackebrandtKlaas imt}, number = 1, pages = {015013}, title = {Detection of the venous oxygen saturation in an oxygenation and perfusion model}, volume = 2, year = 2016 }
• Schmidt, D., Graeser, M., Gladiss, A. von, Buzug, T. M. and Steinhoff, U.: Imaging Characterization of MPI Tracers Employing Offset Measurements in a two Dimensional Magnetic Particle Spectrometer, International Journal on Magnetic Particle Imaging, 2(1), 2016.
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  @article{schmidt_imaging_2016, abstract = {We developed a method to characterize the imaging performance of {MPI} tracers from virtual {MPI} measurements that can be synthesized using measurement data from a Magnetic Particle Spectrometer ({MPS}) at different static magnetic field offsets. {MPI} system functions were obtained from measurements on a {FeraSpin}™ R ({nanoPET} {GmbH}, Berlin) sample in a 2D {MPS} comprising two excitation coils and two receive coils. Software phantoms of spatial {MPI} tracer distributions with different size and shape were constructed. With the measured {MPI} system function, a synthetic {MPI} measurement of the software phantoms was simulated. By adding noise to the virtual {MPI} data, the detection limit of each harmonic in dependence of the noise level was obtained. An {MPI} reconstruction of the virtual tracer distribution was performed using the virtual {MPI} data as input. By comparing the reconstructed images with the actual software phantoms, we obtained the spatial resolution of {MPI} of the investigated tracers. This method might help predicting the image resolution for real {MPI} setups. Our characterization method provides a valuable link between pure spectroscopic characterization and time consuming {MPI} phantom experiments.}, author = {Schmidt, Daniel and Graeser, Matthias and Gladiss, Anselm von and Buzug, Thorsten M. and Steinhoff, Uwe}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {GladissAnselm GraeserMatthias MPS buzugthorsten imt mpi}, number = 1, title = {Imaging Characterization of {MPI} Tracers Employing Offset Measurements in a two Dimensional Magnetic Particle Spectrometer}, volume = 2, year = 2016 }
• Ahlborg, M., Kaethner, C., Knopp, T., Szwargulski, P. and Buzug, T. M.: Using data redundancy gained by patch overlaps to reduce truncation artifacts in magnetic particle imaging, Physics in Medicine and Biology, 61(12), 4583, 2016, DOI: 10.1088/0031-9155/61/12/4583.
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  @article{0031-9155-61-12-4583, abstract = {The imaging technology magnetic particle imaging allows the detection of magnetic material, in particular superparamagnetic nanoparticles, by remagnetization of the material via magnetic fields. The application is aimed at medical imaging where the particles are applied as tracer directly into the blood stream. Medical safety considerations such as peripheral nerve stimulation limit the maximal amplitude of the magnetic fields and in turn the field of view size. To handle this constraint the concept of patches was introduced, which allows a shift of a field of view to different positions in order to enlarge the imaging area. If this is done statically an overlap of patches can be used to reduce truncation artifacts occurring at the adjacent edges. In this contribution, a differentiation of two different kinds of patch overlaps, i.e. a trajectory and a system matrix overlap, is made. Further, different concepts to combine the resulting redundant information are investigated with respect to the reduction of truncation artifacts. The methods are analyzed in detail in a simulation study and validated on experimental data.}, author = {Ahlborg, M and Kaethner, C and Knopp, T and Szwargulski, P and Buzug, T M}, journal = {Physics in Medicine and Biology}, keywords = {MPITheo ahlborgmandy buzugthorsten imt kaethnerchristian}, number = 12, pages = 4583, title = {Using data redundancy gained by patch overlaps to reduce truncation artifacts in magnetic particle imaging}, volume = 61, year = 2016 }
• Rackebrandt, K. and Gehring, H.: Calibration and evaluation of a continuous wave multi-distance NIRS system in simulated desaturation investigations, Biomedical Physics & Engineering Express, 2(3), 035017, 2016.
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  @article{2057-1976-2-3-035017, abstract = {The venous oxygen saturation reflects pathophysiological changes in oxygen delivery and consumption, where the saturation range beneath 50% may represent a clinical borderline to avoid irreversible damage. We present a model to simulate a desaturation investigation with 4 plateaus (PL 1 = 99 ± 0.3%; PL 2 = 75 ± 3%; PL 3 = 50 ± 3%, PL 4 = 25 ± 3%). A continuous wave multi-distance near-infrared spectroscopy sensor (wavelengths: 770, 808 and 850 nm; 6 photodiodes (PD 1−6 ), linearly arranged, separated 6 mm each) was equipped to detect the saturation at these plateaus. The study was divided in 5 calibration experiments (1 day; 5 per day) and 25 experiments (5 days; 5 per day) with the calibrated sensor unit. The detected saturation was compared with the reference values from the CO-Oximetry unit (IL-682) while keeping the amount of total hemoglobin (tHb) and the other physiological parameters at constant levels (tHb = 12 ± 0.3 g dl −1 , blood temperature = 35.5 ± 0.6 °C, carbon dioxide partial pressure (pCO 2 ) = 39 ± 6 mmHg, glucose = 103 ± 9 mg dl −1 and pH 7.4 ± 0.04). The oxygen saturation, in the range from 99% to 20%, could be detected reproducible with a mean absolute deviation of 3%.}, author = {Rackebrandt, K and Gehring, H}, journal = {Biomedical Physics & Engineering Express}, keywords = {RackebrandtKlaas imt}, number = 3, pages = {035017}, title = {Calibration and evaluation of a continuous wave multi-distance NIRS system in simulated desaturation investigations}, volume = 2, year = 2016 }
• Graeser, M., Bente, K., Neumann, A. and Buzug, T. M.: Trajectory dependent particle response for anisotropic mono domain particles in magnetic particle imaging, Journal of Physics D: Applied Physics, 49(4), 045007, 2016.
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  @article{0022-3727-49-4-045007, abstract = {In magnetic particle imaging, scanners use different spatial sampling techniques to cover the field of view (FOV). As spatial encoding is realized by a selective low field region (a field-free-point, or field-free-line), this region has to be moved through the FOV on specific sampling trajectories. To achieve these trajectories complex time dependent magnetic fields are necessary. Due to the superposition of the selection field and the homogeneous time dependent fields, particles at different spatial positions experience different field sequences. As a result, the dynamic behaviour of those particles can be strongly spatially dependent. So far, simulation studies that determined the trajectory quality have used the Langevin function to model the particle response. This however, neglects the dynamic relaxation of the particles, which is highly affected by magnetic anisotropy. More sophisticated models based on stochastic differential equations that include these effects were only used for one dimensional excitation. In this work, a model based on stochastic differential equations is applied to two-dimensional trajectory field sequences, and the effects of these field sequences on the particle response are investigated. The results show that the signal of anisotropic particles is not based on particle parameters such as size and shape alone, but is also determined by the field sequence that a particle ensemble experiences at its spatial position. It is concluded, that the particle parameters can be optimized in terms of the used trajectory.}, author = {Graeser, M. and Bente, K. and Neumann, A. and Buzug, T.M.}, journal = {Journal of Physics D: Applied Physics}, keywords = {BuzugThorsten GraeserMatthias IMT NeumannAlexander}, number = 4, pages = {045007}, title = {Trajectory dependent particle response for anisotropic mono domain particles in magnetic particle imaging}, volume = 49, year = 2016 }
• Erb, W., Kaethner, C., Ahlborg, M. and Buzug, T. M.: Bivariate Lagrange interpolation at the node points of non-degenerate Lissajous curves, Numerische Mathematik, 133(4), 685--705, 2016, DOI: 10.1007/s00211-015-0762-1.
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  @article{Erb2015a, author = {Erb, Wolfgang and Kaethner, Christian and Ahlborg, Mandy and Buzug, ThorstenM.}, journal = {Numerische Mathematik}, keywords = {AhlborgMandy BuzugThorsten IMT KaethnerChristian}, number = 4, pages = {685--705}, publisher = {Springer Berlin Heidelberg}, title = {Bivariate Lagrange interpolation at the node points of non-degenerate Lissajous curves}, volume = 133, year = 2016 }
• Shemesh, N., Jespersen, S. N., Alexander, D. C., Cohen, Y., Drobnjak, I., Dyrby, T. B., Finsterbusch, J., Koch, M. A., Kuder, T., Laun, F., Lawrenz, M., Lundell, H., Mitra, P. P., Nilsson, M., Özarslan, E., Topgaard, D. and Westin, C. -F.: Conventions and Nomenclature for Double Diffusion Encoding NMR and MRI, Magnetic Resonance in Medicine, 75(1), 82--87, 2016, DOI: 10.1002/mrm.25901.
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  @article{Koch2015a, abstract = {Stejskal and Tanner's ingenious pulsed field gradient design from 1965 has made diffusion NMR and MRI the mainstay of most studies seeking to resolve microstructural information in porous systems in general and biological systems in particular. Methods extending beyond Stejskal and Tanner's design, such as double diffusion encoding (DDE) NMR and MRI, may provide novel quantifiable metrics that are less easily inferred from conventional diffusion acquisitions. Despite the growing interest on the topic, the terminology for the pulse sequences, their parameters, and the metrics that can be derived from them remains inconsistent and disparate among groups active in DDE. Here, we present a consensus of those groups on terminology for DDE sequences and associated concepts. Furthermore, the regimes in which DDE metrics appear to provide microstructural information that cannot be achieved using more conventional counterparts (in a model-free fashion) are elucidated. We highlight in particular DDE's potential for determining microscopic diffusion anisotropy and microscopic fractional anisotropy, which offer metrics of microscopic features independent of orientation dispersion and thus provide information complementary to the standard, macroscopic, fractional anisotropy conventionally obtained by diffusion MR. Finally, we discuss future vistas and perspectives for DDE. Magn Reson Med 75:82–87, 2016. © 2015 Wiley Periodicals, Inc.}, author = {Shemesh, Noam and Jespersen, Sune N. and Alexander, Daniel C. and Cohen, Yoram and Drobnjak, Ivana and Dyrby, Tim B. and Finsterbusch, Jurgen and Koch, Martin A. and Kuder, Tristan and Laun, Fredrik and Lawrenz, Marco and Lundell, Henrik and Mitra, Partha P. and Nilsson, Markus and Özarslan, Evren and Topgaard, Daniel and Westin, Carl-Fredrik}, journal = {Magnetic Resonance in Medicine}, keywords = {DiffusionWeighting IMT KochMartin MR}, number = 1, pages = {82--87}, title = {Conventions and Nomenclature for Double Diffusion Encoding {NMR} and {MRI}}, volume = 75, year = 2016 }
• Kaethner, C., Erb, W., Ahlborg, M., Szwargulski, P., Knopp, T. and Buzug, T. M.: Non-Equispaced System Matrix Acquisition for Magnetic Particle Imaging based on Lissajous Node Points, IEEE Transactions on Medical Imaging, PP(99), 1-1, 2016, DOI: 10.1109/TMI.2016.2580458.
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  @article{7490369, abstract = {Magnetic Particle Imaging (MPI) is an emerging technology in the field of (pre)clinical imaging. The acquisition of a particle signal is realized along specific sampling trajectories covering a defined field of view (FOV). In a system matrix (SM) based reconstruction procedure, the commonly used acquisition path in MPI is a Lissajous trajectory. Such a trajectory features an inhomogeneous coverage of the FOV, i.e. the center region is sampled less dense than the regions towards the edges of the FOV. Conventionally, the respective SM acquisition and the subsequent reconstruction do not reflect this inhomogeneous coverage. Instead, they are performed on an equispaced grid. The objective of this work is to introduce a sampling grid that inherently features the aforementioned inhomogeneity by using node points of Lissajous trajectories. Paired with a tailored polynomial interpolation of the reconstructed MPI signal, the entire image can be recovered. It is the first time that such a trajectory related non-equispaced grid is used for image reconstruction on simulated and measured MPI data and it is shown that the number of sampling positions can be reduced, while the spatial resolution remains constant.}, author = {Kaethner, C. and Erb, W. and Ahlborg, M. and Szwargulski, P. and Knopp, T. and Buzug, T. M.}, journal = {IEEE Transactions on Medical Imaging}, keywords = {IMT KaethnerChristian MPITheo ahlborgmandy buzugthorsten}, number = 99, pages = {1-1}, title = {Non-Equispaced System Matrix Acquisition for Magnetic Particle Imaging based on Lissajous Node Points}, volume = {PP}, year = 2016 }
• Schmiedel, M., Möller, A., Koch, M. A. and Mertins, A.: Designing a compact MRI motion phantom, Current Directions in Biomedical Engineering, 2(1), 417--474, 2016, DOI: 10.1515/cdbme-2016-0104.
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  @article{schmiedel2016design, author = {Schmiedel, Max and Möller, Anita and Koch, Martin A. and Mertins, A.}, booktitle = {Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung, Oct 4-6, 2016, Basel}, journal = {Current Directions in Biomedical Engineering}, keywords = {IMT KochMartin MR myown}, number = 1, pages = {417--474}, title = {Designing a compact {MRI} motion phantom}, volume = 2, year = 2016 }
• Gillam, J. E. and Rafecas, M.: Monte-Carlo simulations and image reconstruction for novel imaging scenarios in emission tomography, Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 809, 76 - 88, 2016, DOI: 10.1016/j.nima.2015.09.084.
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  @article{Gillam201676, abstract = {Abstract Emission imaging incorporates both the development of dedicated devices for data acquisition as well as algorithms for recovering images from that data. Emission tomography is an indirect approach to imaging. The effect of device modification on the final image can be understood through both the way in which data are gathered, using simulation, and the way in which the image is formed from that data, or image reconstruction. When developing novel devices, systems and imaging tasks, accurate simulation and image reconstruction allow performance to be estimated, and in some cases optimized, using computational methods before or during the process of physical construction. However, there are a vast range of approaches, algorithms and pre-existing computational tools that can be exploited and the choices made will affect the accuracy of the in silico results and quality of the reconstructed images. On the one hand, should important physical effects be neglected in either the simulation or reconstruction steps, specific enhancements provided by novel devices may not be represented in the results. On the other hand, over-modeling of device characteristics in either step leads to large computational overheads that can confound timely results. Here, a range of simulation methodologies and toolkits are discussed, as well as reconstruction algorithms that may be employed in emission imaging. The relative advantages and disadvantages of a range of options are highlighted using specific examples from current research scenarios.}, author = {Gillam, John E. and Rafecas, Magdalena}, journal = {Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment}, keywords = {RafecasMagdalena imt myown}, month = {February}, note = {Advances in detectors and applications for medicine}, pages = {76 - 88}, title = {Monte-Carlo simulations and image reconstruction for novel imaging scenarios in emission tomography}, volume = 809, year = 2016 }
• Solevi, P., Muñoz, E., Solaz, C., Trovato, M., Dendooven, P., Gillam, J. E., Lacasta, C., Oliver, J. F., Rafecas, M., Torres-Espallardo, I. and Llosá, G.: Performance of MACACO Compton telescope for ion-beam therapy monitoring: first test with proton beams, Physics in Medicine and Biology, 61(14), 5149-5165, 2016, DOI: 10.1088/0031-9155/61/14/5149.
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  @article{0031-9155-61-14-5149, abstract = {In order to exploit the advantages of ion-beam therapy in a clinical setting, delivery verification techniques are necessary to detect deviations from the planned treatment. Efforts are currently oriented towards the development of devices for real-time range monitoring. Among the different detector concepts proposed, Compton cameras are employed to detect prompt gammas and represent a valid candidate for real-time range verification. We present the first on-beam test of MACACO, a Compton telescope (multi-layer Compton camera) based on lanthanum bromide crystals and silicon photo-multipliers. The Compton telescope was first characterized through measurements and Monte Carlo simulations. The detector linearity was measured employing 22 Na and Am-Be sources, obtaining about 10% deviation from linearity at 3.44 MeV. A spectral image reconstruction algorithm was tested on synthetic data. Point-like sources emitting gamma rays with energy between 2 and 7 MeV were reconstructed with 3–5 mm resolution. The two-layer Compton telescope was employed to measure radiation emitted from a beam of 150 MeV protons impinging on a cylindrical PMMA target. Bragg-peak shifts were achieved via adjustment of the PMMA target location and the resulting measurements used during image reconstruction. Reconstructed Bragg peak profiles proved sufficient to observe peak-location differences within 10 mm demonstrating the potential of the MACACO Compton Telescope as a monitoring device for ion-beam therapy.}, author = {Solevi, Paola and Muñoz, Enrique and Solaz, Carles and Trovato, Marco and Dendooven, Peter and Gillam, John E and Lacasta, Carlos and Oliver, Josep F and Rafecas, Magdalena and Torres-Espallardo, Irene and Llosá, Gabriela}, journal = {Physics in Medicine and Biology}, keywords = {RafecasMagdalena imt myown}, number = 14, pages = {5149-5165}, title = {Performance of MACACO Compton telescope for ion-beam therapy monitoring: first test with proton beams}, volume = 61, year = 2016 }
• Nothnagel, N., Rahmer, J., Gleich, B., Halkola, A., Buzug, T. and Borgert, J.: Steering of Magnetic Devices with a Magnetic Particle Imaging System, IEEE Transactions on Biomedical Engineering, PP(99), 7396945, 2016, DOI: 10.1109/TBME.2016.2524070.
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  @article{7396945, abstract = {Small magnetic devices have been steered in arbitrary direction and with variable force using a preclinical demonstrator system for magnetic particle imaging (MPI). Fast localization due to the high imaging rate of over 40 volumes per second and strong forces due to the high field gradient of more than 1 T/m render an MPI system a good platform for image-guided steering of magnetic devices. In this paper, these capabilities are demonstrated in phantom experiments, where a closed feedback loop has been realized to exert translational forces in horizontal and vertical direction on a magnetic device moving in a viscous medium. The MPI system allows for the controlled application of those forces by combining variable homogeneous fields with strong field gradients.}, author = {Nothnagel, N. and Rahmer, J. and Gleich, B. and Halkola, A. and Buzug, T. and Borgert, J.}, journal = {IEEE Transactions on Biomedical Engineering}, keywords = {buzugthorsten imt samba}, number = 99, pages = 7396945, title = {Steering of Magnetic Devices with a Magnetic Particle Imaging System}, volume = {PP}, year = 2016 }
• Maass, M., Bente, K., Ahlborg, M., Medimagh, H., Phan, H., Buzug, T. M. and Mertins, A.: Optimized Compression of MPI System Matrices Using a Symmetry-Preserving Secondary Orthogonal Transform, International Journal on Magnetic Particle Imaging, 2(1), 1607002, 2016, DOI: 10.18416/ijmpi.2016.1607002.
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  @article{maass2016optimized, author = {Maass, Marco and Bente, Klaas and Ahlborg, Mandy and Medimagh, Hanne and Phan, Huy and Buzug, Thorsten M. and Mertins, Alfred}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {ahlborgmandy buzugthorsten imt mpitheo}, number = 1, pages = 1607002, title = {Optimized Compression of MPI System Matrices Using a Symmetry-Preserving Secondary Orthogonal Transform}, volume = 2, year = 2016 }
• Kluck, C. and Buzug, T. M.: Numerical simulations of airflow in the human pharynx of OSAHS patients, Current Directions in Biomedical Engineering, 1(1), 552-555, 2016, DOI: 10.1515/cdbme-2016-0003.
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  @article{kluck2016numerical, author = {Kluck, Christina and Buzug, Thorsten M.}, journal = {Current Directions in Biomedical Engineering}, keywords = {AirflowSimulation HagenChristina KluckChristina buzugthorsten imt}, month = {jun}, number = 1, pages = {552-555}, title = {Numerical simulations of airflow in the human pharynx of OSAHS patients}, volume = 1, year = 2016 }
• Oliver, J. F. and Rafecas, M.: Modelling Random Coincidences in Positron Emission Tomography by Using Singles and Prompts: A Comparison Study, PLoS ONE, 11(9), e0162096, 2016.
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  @article{oliverjf2016modelling, author = {Oliver, J. F. and Rafecas, M.}, journal = {PLoS ONE}, keywords = {RafecasMagdalena imt myown}, number = 9, pages = {e0162096}, title = {Modelling Random Coincidences in Positron Emission Tomography by Using Singles and Prompts: A Comparison Study}, volume = 11, year = 2016 }
• Brzeziński, K., Oliver, J. F., Gillam, J., Rafecas, M., Studen, A., Grkovski, M., Kagan, H., Smith, S., Llosá, G., Lacasta, C. and Clinthorne, N. H.: Experimental evaluation of the resolution improvement provided by a silicon PET probe, Journal of Instrumentation, 11(9), P09016, 2016.
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  @article{brzezinski2016experimental, author = {Brzeziński, K. and Oliver, J.F. and Gillam, J. and Rafecas, M. and Studen, A. and Grkovski, M. and Kagan, H. and Smith, S. and Llosá, G. and Lacasta, C. and Clinthorne, N.H}, journal = {Journal of Instrumentation}, keywords = {IMT RafecasMagdalena myown}, number = 9, pages = {P09016}, title = {Experimental evaluation of the resolution improvement provided by a silicon PET probe}, volume = 11, year = 2016 }
• Malhotra, A., Spieß, F., Stegelmeier, C., Debbeler, C. and Lüdtke-Buzug, K.: Effect of key parameters on synthesis of superparamagnetic nanoparticles (SPIONs), Current Directions in Biomedical Engineering, 2(1), 529-532, 2016, DOI: 10.1515/cdbme-2016-0117.
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  @article{noauthororeditor, abstract = {There are various methods to synthesize superparamagnetic nanoparticles (SPIONs) useful for MPI (magnetic particle imaging) and in therapy (Hypothermia) such as co-precipitation, hydrothermal reactions etc. In this research, the focus is to analyse the effects of crucial parameters such as effect of molecular mass of dextran and temperature of the co-precipitation. These parameters play a crucial role in the inherent magnetic properties of the resulting SPIONs. The amplitude spectrum and hysteresis curve of the SPIONs is analysed with MPS (magnetic particle spectrometer). PCCS (photon cross-correlation spectroscopy) measurements are done to analyse the size distribution of hydrodynamic diameter the resulting SPIONs.}, author = {Malhotra, Ankit and Spieß, Felix and Stegelmeier, Corinna and Debbeler, Christina and Lüdtke-Buzug, Kerstin}, editor = {Dössel, Olaf}, journal = {Current Directions in Biomedical Engineering}, keywords = {BCE DebbelerChristina MalhotraAnkit SPIO StegelmeierCorinna imt luedtkekerstin myown}, month = {sep}, number = 1, pages = {529-532}, title = {Effect of key parameters on synthesis of superparamagnetic nanoparticles (SPIONs)}, volume = 2, year = 2016 }
• Stille, M. and Buzug, T. M.: Metal artifact reduction by projection replacements and non-local prior image integration, Current Directions in Biomedical Engineering, 1(1), 100-103, 2015, DOI: 10.1515/cdbme-2015-0026.
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  @article{Stille2015b, author = {Stille, M. and Buzug, T.M.}, journal = {Current Directions in Biomedical Engineering}, keywords = {BuzugThorsten CT IMT StilleMaik}, number = 1, pages = {100-103}, publisher = {De Gruyter}, title = {Metal artifact reduction by projection replacements and non-local prior image integration}, volume = 1, year = 2015 }
• Finas, D., Baumann, K., Sydow, L., Heinrich, K., Rody, A., Gräfe, K., Buzug, T. M. and Lüdtke-Buzug, K.: SPIO Detection and Distribution in Biological Tissue - A Murine MPI-SLNB Breast Cancer Model, IEEE Transactions on Magnetics, 51(2), 5400104, 2015, DOI: 10.1109/TMAG.2014.2358272.
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  @article{Finas2015a, abstract = {Surgical breast cancer related staging with radical axillary lymph node extraction was mandatory in past times. High morbidity and significant loss of quality of life was inevitable. By introduction of the concept of sentinel lymph node biopsy (SLNB), these adverse effects decreased. Detection of sentinel lymph nodes (SNLs) is realized by the use of dyes and radio nuclides as tracer substances. These tracers can be replaced by superparamagnetic iron oxide nanoparticles (SPIOs) in the near future. Magnetic particle imaging (MPI) guided 3-D real-time imaging and a distinct localization of SPIOs can be achieved in SLNB by the use of MPI. However, qualitative and quantitative enrichment of SPIOs in biologic tissue, in particular, the axillary lymphatic tissue is unexplored until now. We aim to prove the principle of SLNB with MPI within a healthy and than in a tumor bearing mouse model with metastatic axillary lymph nodes in breast cancer. Axillary tissue, surrounding tissues, and tissue from the whole body are analyzed with the following techniques: histology, Prussian blue staining, electron microscopy, atomic absorption spectrometry, and magnetic particle spectroscopy. We found that the SPIOs moves from the injection site through the lymph-fat tissue to the axillary region and finally into the axillary lymph nodes. SPIOs follow traces of lymphatic vessels, respecting borders, and spaces between different tissues. They accumulate near collagen fibers and distinct regions. We present our results of the approach of SLNB with MPI. Application of SPIOs and tracer detection in SNLs with MPI as a new SLNB technology could be less complex and incriminating for patient and staff and could make SLNB more accurate. To realize this approach, an MPI hand probe for intraoperative use is under construction. This will simplify SNL detection and helps to reduce axillary exploration morbidity by avoidance of intensive surgical quest. The tracer for MPI is easy to obtain and this make- the method accessible to many patients. The concept of SLNB by MPI may be applied in principle in all solid tumors.}, author = {Finas, D. and Baumann, K. and Sydow, L. and Heinrich, K. and Rody, A. and Gräfe, K. and Buzug, T.M. and Lüdtke-Buzug, K.}, journal = {IEEE Transactions on Magnetics}, keywords = {BuzugThorsten GraefeKsenija IMT LuedtkeKerstin SingleSided}, month = {feb}, number = 2, pages = 5400104, title = {SPIO Detection and Distribution in Biological Tissue - A Murine MPI-SLNB Breast Cancer Model}, volume = 51, year = 2015 }
• Rackebrandt, K. and Gehring, H.: Measuring different oxygenation levels in a blood perfusion model simulating the human head using NIRS, Current Directions in Biomedical Engineering, 1, 371--, 2015, DOI: 10.1515/cdbme-2015-0091.
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  @article{rackebrandt2015measuring, author = {Rackebrandt, K. and Gehring, H.}, booktitle = {Current Directions in Biomedical Engineering}, keywords = {RackebrandtKlaas imt}, pages = {371--}, title = {Measuring different oxygenation levels in a blood perfusion model simulating the human head using NIRS}, volume = 1, year = 2015 }
• Weber, A., Weizenecker, J., Heinen, U., Heidenreich, M. and Buzug, T. M.: Reconstruction Enhancement by Denoising the Magnetic Particle Imaging System Matrix Using Frequency Domain Filter, IEEE Transactions on Magnetics, 51(2), 7067539, 2015, DOI: 10.1109/TMAG.2014.2332612.
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  @article{7067539, abstract = {Magnetic particle imaging is a new modality, which allows the determination of the spatial distribution of magnetic nanoparticles in-vivo. A standard approach for magnetic particle image reconstruction employs a so-called system matrix. The system matrix is typically acquired by a calibration measurement, whereby the system response at numerous positions in the field-of-view is measured. Due to the measurement process, the system matrix contains noise, which affects the reconstruction of the particle distribution. In this paper, the special structure of the system matrix is exploited for noise reduction by applying frequency domain filters. It is shown that image reconstruction with the denoised system matrix yields an improved resolution and a better signal-to-noise ratio.}, author = {Weber, A. and Weizenecker, J. and Heinen, U. and Heidenreich, M. and Buzug, T.M.}, journal = {IEEE Transactions on Magnetics}, keywords = {buzugthorsten imt}, month = {feb}, number = 2, pages = 7067539, title = {Reconstruction Enhancement by Denoising the Magnetic Particle Imaging System Matrix Using Frequency Domain Filter}, volume = 51, year = 2015 }
• Weber, M., Bente, K., Graeser, M., Sattel, T. F. and Buzug, T. M.: Implementation of a High-Precision 2-D Receiving Coil Set for Magnetic Particle Imaging, IEEE Transactions on Magnetics, 51(2), 6502404, 2015, DOI: 10.1109/TMAG.2014.2331987.
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  @article{Weber2014b, abstract = {In the medical imaging technique magnetic particle imaging, tomographic images of the spatial distribution of superparamagnetic particles are produced in real time. To generate images in a plane, the particles are excited in two dimensions. A specific particle response can be measured via receiving coils and the measured signal gives quantitative information about the particle distribution and local concentration. To achieve a high-spatial resolution with x-space reconstruction, the receiving coils have to feature a preferably homogeneous sensitivity in the field of view. To achieve this for a cylindrical bore, which is the typical medical scenario, an optimized coil set is implemented and tested in this paper. Two orthogonal receiving coil pairs are wound inside a negative form, which is custom made by a 3-D printer. Further, a well performing receiving chain is utilized, which transmits the particle signal from the receiving coils to the data acquisition unit. For performance evaluation, a hardware phantom with three delta samples is used. A field free line is chosen as a selection field, for which the presented coils may be used in an application scenario. The receiving coils perform well in the sense that no coupling in between the data paths is apparent and the recorded signals clearly represent the used phantom.}, author = {Weber, M. and Bente, K. and Graeser, M. and Sattel, T. F. and Buzug, T. M.}, journal = {IEEE Transactions on Magnetics}, keywords = {BuzugThorsten GraeserMatthias IMT LUMEN WeberMatthias}, month = {feb}, number = 2, pages = 6502404, title = {Implementation of a High-Precision 2-D Receiving Coil Set for Magnetic Particle Imaging}, volume = 51, year = 2015 }
• Erb, W., Kaethner, C., Denker, P. and Ahlborg, M.: A survey on bivariate Lagrange interpolation on Lissajous nodes, Dolomites Research Notes on Approximation, 8, 23-36, 2015, DOI: 10.14658/pupj-drna-2015-Special_Issue-4.
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  @article{Erb2015b, author = {Erb, W. and Kaethner, C. and Denker, P. and Ahlborg, M.}, journal = {Dolomites Research Notes on Approximation}, keywords = {AhlborgMandy IMT KaethnerChristian}, pages = {23-36}, title = {A survey on bivariate Lagrange interpolation on Lissajous nodes}, volume = 8, year = 2015 }
• Szwargulski, P., Rahmer, J., Ahlborg, M., Kaethner, C. and Buzug, T. M.: Experimental Evaluation of Different Weighting Schemes in Magnetic Particle Imaging Reconstruction, Student Conference Medical Engineering Science, 4, 2015.
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  @article{Szwargulski2015b, author = {Szwargulski, P. and Rahmer, J. and Ahlborg, M. and Kaethner, C. and Buzug, T. M.}, journal = {Student Conference Medical Engineering Science}, keywords = {AhlborgMandy BuzugThorsten IMT KaethnerChristian MPI}, title = {Experimental Evaluation of Different Weighting Schemes in Magnetic Particle Imaging Reconstruction}, volume = 4, year = 2015 }
• Medimagh, H., Weissert, P., Bringout, G., Bente, K., Weber, M., Gräfe, K., Cordes, A. and Buzug, T. M.: Artifacts in field free line magnetic particle imaging in the presence of inhomogeneous and nonlinear magnetic fields, Current Directions in Biomedical Engineering, 1(1), 245-248, 2015, DOI: 10.1515/cdbme-2015-0061.
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  @article{Medimagh2015c, author = {Medimagh, H. and Weissert, P. and Bringout, G. and Bente, K. and Weber, M. and Gräfe, K. and Cordes, A. and Buzug, T.M.}, journal = {Current Directions in Biomedical Engineering}, keywords = {BringoutGael BuzugThorsten CordesAileen GraefeKsenija IMT MAPIT MPITheo MedimaghHanne WeberMatthias}, number = 1, pages = {245-248}, title = {Artifacts in field free line magnetic particle imaging in the presence of inhomogeneous and nonlinear magnetic fields}, volume = 1, year = 2015 }
• Ulloa, P., Wottschel, V. and Koch, A. M.: Studying the extracellular contribution to the double wave vector diffusion-weighted signal, Current Directions in Biomedical Engineering, 1(1), 240-244, 2015, DOI: 10.1515/cdbme-2015-0060.
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  @article{Ulloa2015b, author = {Ulloa, P. and Wottschel, V. and Koch, A.M.}, journal = {Current Directions in Biomedical Engineering}, keywords = {DiffusionWeighting IMT KochMartin MR UlloaPatricia}, number = 1, pages = {240-244}, title = {Studying the extracellular contribution to the double wave vector diffusion-weighted signal}, volume = 1, year = 2015 }
• Debbeler, C., Boy, A. and Lüdtke-Buzug, K.: Synthesis of Superparamagnetic Iron Oxide Nanoparticles under Ultrasound Control, Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung, 60(s1), s-27, 2015, DOI: 10.1515/bmt-2015-5000.
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  @article{Debbeler2015b, author = {Debbeler, C. and Boy, A. and Lüdtke-Buzug, K.}, journal = {Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung}, keywords = {BCE DebbelerChristina IMT LuedtkeKerstin SPIO}, number = {s1}, pages = {s-27}, title = {Synthesis of Superparamagnetic Iron Oxide Nanoparticles under Ultrasound Control}, volume = 60, year = 2015 }
• Kaethner, C., Ahlborg, M., Bringout, G., Weber, M. and Buzug, T. M.: Axially Elongated Field-Free Point Data Acquisition in Magnetic Particle Imaging, IEEE Transactions on Medical Imaging, 34(2), 381-387, 2015, DOI: 10.1109/TMI.2014.2357077.
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  @article{Kaethner2015a, abstract = {The magnetic particle imaging (MPI) technology is a new imaging technique featuring an excellent possibility to detect iron oxide based nanoparticle accumulations in vivo. The excitation of the particles and in turn the signal generation in MPI are achieved by using oscillating magnetic fields. In order to realize a spatial encoding, a field-free point (FFP) is steered through the field of view (FOV). Such a positioning of the FFP can thereby be achieved by mechanical or electromagnetical movement. Conventionally, the data acquisition path is either a planar 2-D or a 3-D FFP trajectory. Assuming human applications, the size of the FOV sampled by such trajectories is strongly limited by heating of the body and by nerve stimulations. In this work, a new approach acquiring MPI data based on the axial elongation of a 2-D FFP trajectory is proposed. It is shown that such an elongation can be used as a data acquisition path to significantly increase the acquisition speed, with negligible loss of spatial resolution.}, author = {Kaethner, C. and Ahlborg, M. and Bringout, G. and Weber, M. and Buzug, T.M.}, journal = {IEEE Transactions on Medical Imaging}, keywords = {AhlborgMandy BringoutGael BuzugThorsten IMT KaethnerChristian MPITheo WeberMatthias}, month = {feb}, number = 2, pages = {381-387}, title = {Axially Elongated Field-Free Point Data Acquisition in Magnetic Particle Imaging}, volume = 34, year = 2015 }
• v. Gladiß, A., Graeser, M., Lüdtke-Buzug, K. and Buzug, T. M.: Contribution of brownian rotation and particle assembly polarisation to the particle response in magnetic particle spectrometry, Current Directions in Biomedical Engineering, 1(1), 298-301, 2015, DOI: 10.1515/cdbme-2015-0074.
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  @article{Gladiss2015c, author = {v. Gladiß, A. and Graeser, M. and Lüdtke-Buzug, K. and Buzug, T. M}, journal = {Current Directions in Biomedical Engineering}, keywords = {BuzugThorsten GladissAnselm GraeserMatthias IMT LuedtkeKerstin MPS}, number = 1, pages = {298-301}, title = {Contribution of brownian rotation and particle assembly polarisation to the particle response in magnetic particle spectrometry}, volume = 1, year = 2015 }
• Bringout, G., Gräfe, K. and Buzug, T. M.: Performance of Shielded Electromagnet-Evaluation Under Low-Frequency Excitation, IEEE Transactions on Magnetics, 51(2), 1-4, 2015, DOI: 10.1109/TMAG.2014.2329396.
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  @article{7067543, author = {Bringout, G. and Gräfe, K. and Buzug, T. M.}, journal = {IEEE Transactions on Magnetics}, keywords = {BringoutGael BuzugThorsten GraefeKsenija IMT MAPIT}, month = {feb}, number = 2, pages = {1-4}, title = {Performance of Shielded Electromagnet-Evaluation Under Low-Frequency Excitation}, volume = 51, year = 2015 }
• Kläser, K., Graeser, M., Steinhagen, D. and Lüdtke-Buzug, K.: Construction of a device for magnetic separation of superparamagnetic iron oxide nanoparticles, Current Directions in Biomedical Engineering, 1(1), 306--309, 2015, DOI: 10.1515/cdbme-2015-0076.
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  @article{Luedtke-Buzug2015a, author = {Kläser, K. and Graeser, M. and Steinhagen, D. and Lüdtke-Buzug, K.}, journal = {Current Directions in Biomedical Engineering}, keywords = {BCE GraeserMatthias IMT LuedtkeKerstin SPIO}, number = 1, pages = {306--309}, title = {Construction of a device for magnetic separation of superparamagnetic iron oxide nanoparticles}, volume = 1, year = 2015 }
• Szwargulski, P., Ahlborg, M., Kaethner, C. and Buzug, T. M.: Trajectory Analysis Using Static Patches for Magnetic Particle Imaging, IEEE Transactions on Magnetics, 51(2), 1-4, 2015, DOI: 10.1109/TMAG.2014.2350152.
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  @article{Szwargulski2015a, abstract = {Magnetic particle imaging (MPI) is an imaging technique based on the determination of magnetic material by moving a field-free point along specified trajectories, which are used to sample the field of view. Due to technical and safety reasons, the field of view is limited in size. To enlarge the size of the field of view, trajectory patches are used, which are sampled separately and combined consecutively to an entire field of view. The aim of this paper is to analyze the effect of different trajectories combined with the patch approach. In addition, an empiric study is performed to analyze the influence of overlapped patches on each trajectory combined with cutoff as postprocessing method. As a follow-up, a new patch formation of the radial trajectory based on a phase shift between each of the patches is introduced. Finally, it can be shown that the Lissajous trajectory, which is commonly used for MPI, provides appropriate results. However, the results of overlapped patches with a circular trajectory increase spatial resolution.}, author = {Szwargulski, P. and Ahlborg, M. and Kaethner, C. and Buzug, T. M.}, journal = {IEEE Transactions on Magnetics}, keywords = {AhlborgMandy BuzugThorsten IMT KaethnerChristian MPI}, month = {feb}, number = 2, pages = {1-4}, title = {Trajectory Analysis Using Static Patches for Magnetic Particle Imaging}, volume = 51, year = 2015 }
• Graeser, M., Bente, K., Neumann, A. and Buzug, T. M.: Trajectory Dependent Particle Response for Anisotropic Mono Domain Particles in Magnetic Particle Imaging, Journal of Physics D: Applied Physics, 49(4), 2015, DOI: 10.1088/0022-3727/49/4/045007.
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  @article{Graeser2015c, author = {Graeser, Matthias and Bente, Klaas and Neumann, Alexander and Buzug, Thorsten M.}, journal = {Journal of Physics D: Applied Physics}, keywords = {BuzugThorsten GraeserMatthias IMT MAPIT MPS NeumannAlexander ParticleTheory SAMBA}, number = 4, title = {Trajectory Dependent Particle Response for Anisotropic Mono Domain Particles in Magnetic Particle Imaging}, volume = 49, year = 2015 }
• Gräfe, K., Bringout, G., Graeser, M., Sattel, T. F. and Buzug, T. M.: System Matrix Recording and Phantom Measurements with a Single-Sided Magnetic Particle Imaging Device, IEEE Transactions on Magnetics, 51(2), 6502303, 2015, DOI: 10.1109/TMAG.2014.2330371.
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  @article{Graefe2015a, abstract = {Magnetic particle imaging (MPI) is a new imaging method, which uses superparamagnetic iron oxide nanoparticles as tracer material. Due to their tube-like design, most MPI devices have limited patient access. In this paper, an improved oil-cooled single-sided MPI device is presented that has the advantage that all coils, which are generating the magnetic fields or receiving the particle signal, are coplanar and on one side of the patient only. In consequence, the object, which will be scanned, is not limited in size. In this paper, a first 1-D image recorded with the new device is presented.}, author = {Gräfe, K. and Bringout, G. and Graeser, M. and Sattel, T.F. and Buzug, T.M.}, journal = {IEEE Transactions on Magnetics}, keywords = {BringoutGael BuzugThorsten GraefeKsenija GraeserMatthias IMT SingleSided}, month = {feb}, number = 2, pages = 6502303, title = {System Matrix Recording and Phantom Measurements with a Single-Sided Magnetic Particle Imaging Device}, volume = 51, year = 2015 }
• Kaethner, C., Ahlborg, M., Gräfe, K., Bringout, G., Sattel, T. F. and Buzug, T. M.: Asymmetric Scanner Design for Interventional Scenarios in Magnetic Particle Imaging, IEEE Transactions on Magnetics, 51(2), 1-4, 2015, DOI: 10.1109/TMAG.2014.2337931.
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  @article{Kaethner2015b, abstract = {Magnetic particle imaging is an imaging modality that acquires quantitative information about the spatial distribution of magnetic nanoparticles. In combination with an excellent spatial and temporal resolution and due to the fact that no harmful radiation is used, the imaging technique offers possibilities with respect to medical application. As such, interventional scenarios, where it is mandatory to visualize the used instruments, are a perfectly suitable area of application. This paper describes the results of a feasibility study where a novel single-sided coil arrangement based on approximated elliptical coils is designed to be integrated into a patient table. Using such coils perfectly matches the requirements of good patient access, large field of view (FOV), and available space in the table. A small change in the aspect ratio leads to an enlarged FOV with sufficient gradient strength in all directions.}, author = {Kaethner, C. and Ahlborg, M. and Gräfe, K. and Bringout, G. and Sattel, T.F. and Buzug, T.M.}, journal = {IEEE Transactions on Magnetics}, keywords = {AhlborgMandy BringoutGael BuzugThorsten GraefeKsenija IMT KaethnerChristian}, month = {feb}, number = 2, pages = {1-4}, title = {Asymmetric Scanner Design for Interventional Scenarios in Magnetic Particle Imaging}, volume = 51, year = 2015 }
• Kuschnerus, I. and Lüdtke-Buzug, K.: Development and characterization of superparamagnetic coatings, Current Directions in Biomedical Engineering, 1(1), 1-4, 2015, DOI: 10.1515/cdbme-2015-0001.
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  @article{Luedtke-Buzug2015c, author = {Kuschnerus, I. and Lüdtke-Buzug, K.}, journal = {Current Directions in Biomedical Engineering}, keywords = {IMT LuedtkeKerstin SPIO}, number = 1, pages = {1-4}, title = {Development and characterization of superparamagnetic coatings}, volume = 1, year = 2015 }
• von Gladiß, A., Ahlborg, M., Knopp, T. and Buzug, T. M.: Compressed Sensing of the System Matrix and Sparse Reconstruction of the Particle Concentration in Magnetic Particle Imaging, IEEE Transactions on Magnetics, 51(2), 6501304, 2015, DOI: 10.1109/TMAG.2014.2326432.
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  @article{Gladiss2015a, abstract = {The reconstruction of a particle concentration in magnetic particle imaging is commonly based on using a system matrix, whose acquisition is time consuming and whose storing is challenging. It has been shown recently that the acquisition time can be reduced with methods of compressed sensing and storage requirements can be reduced by storing in sparse representation. To improve the reconstruction, signals of low signal-to-noise ratio (SNR) are discarded. The determination of the SNR is difficult for undersampled signals. In this paper, the mixing order of the acquired harmonics is calculated to estimate the SNR. The spatial resolution of a system matrix can be increased by compressed sensing. A system matrix of small spatial resolution can be fully acquired in the same amount of time as a high resoluted system matrix that is undersampled correspondingly.}, author = {von Gladiß, A. and Ahlborg, M. and Knopp, T. and Buzug, T.M.}, journal = {IEEE Transactions on Magnetics}, keywords = {AhlborgMandy BuzugThorsten GladissAnselm IMT MPITheo}, month = {feb}, number = 2, pages = 6501304, title = {Compressed Sensing of the System Matrix and Sparse Reconstruction of the Particle Concentration in Magnetic Particle Imaging}, volume = 51, year = 2015 }
• Duda, K. and Lüdtke-Buzug, K.: Stability analysis of ferrofluids, Current Directions in Biomedical Engineering, 1(1), 10-13, 2015, DOI: 10.1515/cdbme-2015-0003.
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  @article{Luedtke-Buzug2015b, author = {Duda, K. and Lüdtke-Buzug, K.}, journal = {Current Directions in Biomedical Engineering}, keywords = {IMT LuedtkeKerstin SPIO}, number = 1, pages = {10-13}, title = {Stability analysis of ferrofluids}, volume = 1, year = 2015 }
• Panagiotopoulos, N., Duschka, R. L., Ahlborg, M., Bringout, G., Debbeler, C., Graeser, M., Kaethner, C., Lüdtke-Buzug, K., Medimagh, H., Stelzner, J., Buzug, T. M., Barkhausen, J., Vogt, F. and Haegele, J.: Magnetic particle imaging: current developments and future directions, International Journal of Nanomedicine, 10, 3097-3114, 2015, DOI: 10.2147/ijn.s70488.
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  @article{Panagiotopoulos2015a, author = {Panagiotopoulos, Nikolaos and Duschka, Robert L. and Ahlborg, Mandy and Bringout, Gael and Debbeler, Christina and Graeser, Matthias and Kaethner, Christian and Lüdtke-Buzug, Kerstin and Medimagh, Hanne and Stelzner, Jan and Buzug, Thorsten M. and Barkhausen, Jörg and Vogt, Florian and Haegele, Julian}, journal = {International Journal of Nanomedicine}, keywords = {AhlborgMandy BringoutGael BuzugThorsten DebbelerChristina GraeserMatthias IMT KaethnerChristian LuedtkeKerstin MAPIT MPS MedimaghHanne SPIO StelznerJan}, month = {apr}, pages = {3097-3114}, publisher = {Dove Medical Press Ltd.}, title = {Magnetic particle imaging: current developments and future directions}, volume = 10, year = 2015 }
• Graeser, M., Bente, K. and Buzug, T. M.: Dynamic Single-Domain Particle Model for Magnetite Particles with Combined Crystalline and Shape Anisotropy, Journal of Physics D: Applied Physics, 48(27), 275001, 2015, DOI: 10.1088/0022-3727/48/27/275001.
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  @article{Graeser2015b, author = {Graeser, M. and Bente, K. and Buzug, T. M.}, journal = {Journal of Physics D: Applied Physics}, keywords = {BuzugThorsten GraeserMatthias IMT MPS ParticleTheory SAMBA}, number = 27, pages = 275001, title = {Dynamic Single-Domain Particle Model for Magnetite Particles with Combined Crystalline and Shape Anisotropy}, volume = 48, year = 2015 }
• Szwargulski, P., Rahmer, J., Ahlborg, M., Kaethner, C. and Buzug, T. M.: Experimental Evaluation of Different Weighting Schemes in Magnetic Particle Imaging Reconstruction, Current Directions in Biomedical Engineering 2015, 1(1), 206-209, 2015, DOI: 10.1515/CDBME-2015-0052.
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  @article{Szwargulski2015e, author = {Szwargulski, P. and Rahmer, J. and Ahlborg, M. and Kaethner, C. and Buzug, T. M.}, journal = {Current Directions in Biomedical Engineering 2015}, keywords = {AhlborgMandy BuzugThorsten IMT KaethnerChristian MPITheo}, number = 1, pages = {206-209}, title = {Experimental Evaluation of Different Weighting Schemes in Magnetic Particle Imaging Reconstruction}, volume = 1, year = 2015 }
• Haegele, J., Lüdtke-Buzug, K., Schaecke, C., Graeser, M., Duschka, R. L., Panagiotopoulos, N., Buzug, T. M., Vogt, F. and Barkhausen, J.: Magnetic particle imaging: kinetics of the intravascular signal in vivo, International Journal of Nanomedicine, 4203-4209, 2014, DOI: 10.2147/ijn.s49976.
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  @article{haegele2014, author = {Haegele, Julian and Lüdtke-Buzug, Kerstin and Schaecke, Catharina and Graeser, Matthias and Duschka, Robert L. and Panagiotopoulos, Nikolaos and Buzug, Thorsten M. and Vogt, Florian and Barkhausen, Jörg}, journal = {International Journal of Nanomedicine}, keywords = {BuzugThorsten GraeserMatthias IMT LuedtkeKerstin MPS}, month = {sep}, pages = {4203-4209}, publisher = {Dove Medical Press Ltd.}, title = {Magnetic particle imaging: kinetics of the intravascular signal in vivo}, year = 2014 }
• Bringout, G. and Buzug, T. M.: Coil Design for Magnetic Particle Imaging: Application for a Preclinical Scanner, IEEE Transactions on Magnetics, 51(2), 5100808, 2014, DOI: 10.1109/TMAG.2014.2344917.
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  @article{Bringout2014b, abstract = {A method to design electromagnetic coils for magnetic particle imaging (MPI) scanners is presented. Three different coils for a rabbit sized scanner are designed, namely, a cylindrical drive coil, a biplanar drive coil, and a quadrupole. Based on the inverse boundary elements method, the optimization of all coils used in an MPI scanner is possible. The inverse problem is solved using the Tikhonov regularization and a quadratic programming with quadratic constraints algorithm. Depending on the chosen objectives, the coils can be designed to precisely generate a given field, having a small inductance, resistance, or having a smooth winding pattern. The properties of a cylindrical drive coil are then validated on a prototype. The use of this technique allows the optimization of the scanner design, to enhance the imaging capacity, and to easily gain control over the key properties of the coils in order to scale up scanners to human size.}, author = {Bringout, G. and Buzug, T.M.}, journal = {IEEE Transactions on Magnetics}, keywords = {BringoutGael BuzugThorsten IMT MAPIT}, month = {feb}, number = 2, pages = 5100808, title = {Coil Design for Magnetic Particle Imaging: Application for a Preclinical Scanner}, volume = 51, year = 2014 }
• Wojtczyk, H., Bringout, G., Tenner, W., Graeser, M., Grüttner, M., Sattel, T. F., Gräfe, K. and Buzug, T. M.: Toward the Optimization of D-Shaped Coils for the Use in an Open Magnetic Particle Imaging Scanner, IEEE Transactions on Magnetics, 50(7), 5100507, 2014, DOI: 10.1109/TMAG.2014.2303113.
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  @article{Wojtczyk2014a, abstract = {Magnetic particle imaging (MPI) is a novel medical imaging modality that allows for the quantitative detection of superparamagnetic iron oxide nanoparticles using static and oscillating magnetic fields. Essential aspects in the coil optimization for MPI include the magnetic field generated per unit current and the magnetic field homogeneity. For a set of D-shaped coils, which can be used in an open MPI scanner with lateral patient access to enable multidimensional imaging, these quantities were analyzed for a range of configurations. The results were compared with the situation in a four-wire-model and a four-wire-model with return paths (called eight-wire-model). It was found that for large coil radii, the effects of the D-coil set resemble those of the eight-wire-model; however, the local minimum in the magnetic field inhomogeneity is less pronounced.}, author = {Wojtczyk, H. and Bringout, G. and Tenner, W. and Graeser, M. and Grüttner, M. and Sattel, T.F. and Gräfe, K. and Buzug, T.M.}, journal = {IEEE Transactions on Magnetics}, keywords = {AhlborgMandy BringoutGael BuzugThorsten GraefeKsenija GraeserMatthias IMT MAPIT MPITheo MedimaghHanne}, month = {July}, number = 7, pages = 5100507, title = {Toward the Optimization of D-Shaped Coils for the Use in an Open Magnetic Particle Imaging Scanner}, volume = 50, year = 2014 }
• Baumann, K., Stegmann-Frehse, J., Rody, A., Gräfe, K., Lüdtke-Buzug, K., Buzug, T. and Finas, D.: Weiterentwicklung des SNLB-Konzept unter Verwendung von SPIOs beim Mammakarzinom - Prozessierung der Nanopartikel im Organismus, Senologie, 11-A13, 2014, DOI: 10.1055/s-0034-1375372.
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  @article{Baumann2014a, author = {Baumann, K and Stegmann-Frehse, J and Rody, A and Gräfe, K and Lüdtke-Buzug, K and Buzug, T and Finas, D}, journal = {Senologie}, keywords = {BuzugThorsten GraefeKsenija IMT LuedtkeKerstin SPIO SingleSided}, month = {may}, publisher = {Thieme Publishing Group}, title = {Weiterentwicklung des {SNLB}-Konzept unter Verwendung von {SPIOs} beim Mammakarzinom - Prozessierung der Nanopartikel im Organismus}, volume = {11-A13}, year = 2014 }
• Duschka, R., Wojtczyk, H., Panagiotopoulos, N., Haegele, J., Bringout, G., Buzug, T., Barkhausen, J. and Vogt, F.: Safety Measurements for Heating of Instruments for Cardiovascular Interventions in Magnetic Particle Imaging (MPI) - First Experiences, Journal of Healthcare Engineering, 5(1), 79-94, 2014, DOI: 10.1260/2040-2295.5.1.79.
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  @article{Duschka2014a, author = {Duschka, Robert and Wojtczyk, Hanne and Panagiotopoulos, Nikolaos and Haegele, Julian and Bringout, Gael and Buzug, Thorsten and Barkhausen, Joerg and Vogt, Florian}, journal = {Journal of Healthcare Engineering}, keywords = {BringoutGael BuzugThorsten IMT MAPIT MedimaghHanne}, month = {mar}, number = 1, pages = {79-94}, publisher = {Multi-Science Publishing Co. Ltd.}, title = {Safety Measurements for Heating of Instruments for Cardiovascular Interventions in Magnetic Particle Imaging ({MPI}) - First Experiences}, volume = 5, year = 2014 }
• Lindemann, A., Lüdtke-Buzug, K., Fraederich, B. M., Gräfe, K., Pries, R. and Wollenberg, B.: Biological impact of superparamagnetic iron oxide nanoparticles for magnetic particle imaging of head and neck cancer cells, International Journal of Nanomedicine, 9, 5025–5040, 2014, DOI: 10.2147/ijn.s63873.
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  @article{Lindemann2014a, author = {Lindemann, Antje and Lüdtke-Buzug, Kerstin and Fraederich, Bianca M. and Gräfe, Ksenija and Pries, Ralph and Wollenberg, Barbara}, journal = {International Journal of Nanomedicine}, keywords = {BuzugThorsten GraefeKsenija IMT LuedtkeKerstin SPIO}, month = {oct}, pages = {5025–5040}, publisher = {Dove Medical Press Ltd.}, title = {Biological impact of superparamagnetic iron oxide nanoparticles for magnetic particle imaging of head and neck cancer cells}, volume = 9, year = 2014 }
• Omer, O. A., Wojtczyk, H. and Buzug, T. M.: Simultaneous Reconstruction and Resolution Enhancement for Magnetic Particle Imaging, IEEE Transactions on Magnetics, 51(2), 6500804, 2014, DOI: 10.1109/TMAG.2014.2330553.
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  @article{Omer2014b, abstract = {Spatial resolution is an essential parameter for magnetic particle imaging (MPI). The spatial resolution of MPI depends, among other things, on the particles diameter and sampling frequency. The spatial resolution increases when increasing the particle diameter. However, large particles suffer from relaxation effects and are not preferred in some applications. On the other hand, spatial resolution increases with the sampling frequency, which in turn increases the number of sampling points. As an alternative solution for resolution enhancement, super-resolution (SR) is proved to be beneficial in improving the image quality of many medical imaging systems without the need for significant hardware alteration. In this paper, we propose to use small particle diameter and low sampling frequency to obtain multiple low-resolution (LR) magnetic particle measurements and apply a resolution enhancement technique to reconstruct a higher resolution magnetic particle concentration. Unlike the conventional SR techniques, we propose to reconstruct a high-resolution concentration from the measured LR signals instead of reconstructing LR concentrations and then post-process these concentrations to get a higher resolution concentration. Simulation results show that the resolution of MPI can be increased by incorporating resolution enhancement technique without increasing the particle diameter. In addition, simulation results show that using simultaneous reconstruction and resolution enhancement results in sharper concentrations and that this procedure is more robust against noise than using SR as a post-process.}, author = {Omer, O.A. and Wojtczyk, H. and Buzug, T.M.}, journal = {IEEE Transactions on Magnetics}, keywords = {BuzugThorsten IMT MAPIT MPITheo MedimaghHanne}, month = {feb}, number = 2, pages = 6500804, title = {Simultaneous Reconstruction and Resolution Enhancement for Magnetic Particle Imaging}, volume = 51, year = 2014 }
• Bente, K., Weber, M., Graeser, M., Sattel, T. F., Erbe, M. and Buzug, T. M.: Electronic Field Free Line Rotation and Relaxation Deconvolution in Magnetic Particle Imaging, IEEE Transactions on Medical Imaging, 34(2), 644-651, 2014, DOI: 10.1109/TMI.2014.2364891.
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  @article{Bente2014a, abstract = {It has been shown that magnetic particle imaging (MPI), an imaging method suggested in 2005, is capable of measuring the spatial distribution of magnetic nanoparticles. Since the particles can be administered as biocompatible suspensions, this method promises to perform well as a tracer-based medical imaging technique. It is capable of generating real-time images, which will be useful in interventional procedures, without utilizing any harmful radiation. To obtain a signal from the administered superparamagnetic iron oxide (SPIO) particles, a sinusoidal changing external homogeneous magnetic field is applied. To achieve spatial encoding, a gradient field is superimposed. Conventional MPI works with a spatial encoding field that features a field free point (FFP). To increase sensitivity, an improved spatial encoding field, featuring a field free line (FFL) can be used. Previous FFL scanners, featuring a 1-D excitation, could demonstrate the feasibility of the FFL-based MPI imaging process. In this work, an FFL-based MPI scanner is presented that features a 2-D excitation field and, for the first time, an electronic rotation of the spatial encoding field. Furthermore, the role of relaxation effects in MPI is starting to move to the center of interest. Nevertheless, no reconstruction schemes presented thus far include a dynamical particle model for image reconstruction. A first application of a model that accounts for relaxation effects in the reconstruction of MPI images is presented here in the form of a simplified, but well performing strategy for signal deconvolution. The results demonstrate the high impact of relaxation deconvolution on the MPI imaging process.}, author = {Bente, K. and Weber, M. and Graeser, M. and Sattel, T. F. and Erbe, M. and Buzug, T. M.}, journal = {IEEE Transactions on Medical Imaging}, keywords = {BuzugThorsten IMT LUMEN MPITheo WeberMatthias}, month = {feb}, number = 2, pages = {644-651}, title = {Electronic Field Free Line Rotation and Relaxation Deconvolution in Magnetic Particle Imaging}, volume = 34, year = 2014 }
• Kaethner, C., Ahlborg, M., Knopp, T., Sattel, T. F. and Buzug, T. M.: Efficient gradient field generation providing a multi-dimensional arbitrary shifted field-free point for magnetic particle imaging, Journal of Applied Physics, 115(4), 044910, 2014, DOI: 10.1063/1.4863177.
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  @article{Kaethner2014d, abstract = {Magnetic Particle Imaging (MPI) is a tomographic imaging modality capable to visualize tracers using magnetic fields. A high magnetic gradient strength is mandatory, to achieve a reasonable image quality. Therefore, a power optimization of the coil configuration is essential. In order to realize a multi-dimensional efficient gradient field generator, the following improvements compared to conventionally used Maxwell coil configurations are proposed: (i) curved rectangular coils, (ii) interleaved coils, and (iii) multi-layered coils. Combining these adaptions results in total power reduction of three orders of magnitude, which is an essential step for the feasibility of building full-body human MPI scanners.}, author = {Kaethner, Christian and Ahlborg, Mandy and Knopp, Tobias and Sattel, Timo F. and Buzug, Thorsten M.}, journal = {Journal of Applied Physics}, keywords = {AhlborgMandy BuzugThorsten IMT KaethnerChristian MPITheo}, number = 4, pages = {044910}, title = {Efficient gradient field generation providing a multi-dimensional arbitrary shifted field-free point for magnetic particle imaging}, volume = 115, year = 2014 }
• Henrik, R., Marlitt, E., M., B. T. and Kerstin, L. -B.: Simulation of the magnetization dynamics of diluted ferrofluids in medical applications, Biomedizinische Technik / Biomedical Engineering, 58(6), 601-609, 2013, DOI: 10.1515/bmt-2013-0034.
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  @article{Rogge2013a, author = {Henrik, Rogge and Marlitt, Erbe and M., Buzug Thorsten and Kerstin, Lüdtke-Buzug}, booktitle = {Biomedizinische Technik / Biomedical Engineering}, keywords = {BuzugThorsten IMT LuedtkeKerstin SPIO}, number = 6, pages = {601-609}, title = {Simulation of the magnetization dynamics of diluted ferrofluids in medical applications}, volume = 58, year = 2013 }
• Grüttner, M., Knopp, T., Franke, J., Heidenreich, M., Rahmer, J., Halkola, A., Kaethner, C., Borgert, J. and Buzug, T. M.: On the formulation of the image reconstruction problem in magnetic particle imaging, Biomedizinische Technik / Biomedical Engineering, 58(6), 583-591, 2013, DOI: 10.1515/bmt-2012-0063.
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  @article{Gruettner2013c, author = {Grüttner, M. and Knopp, T. and Franke, J. and Heidenreich, M. and Rahmer, J. and Halkola, A. and Kaethner, C. and Borgert, J. and Buzug, T.M.}, booktitle = {Biomedizinische Technik / Biomedical Engineering}, keywords = {AhlborgMandy BuzugThorsten IMT KaethnerChristian MPITheo}, number = 6, pages = {583-591}, title = {On the formulation of the image reconstruction problem in magnetic particle imaging}, volume = 58, year = 2013 }
• Duschka, R. L., Haegele, J., Panagiotopoulos, N., Wojtczyk, H., Barkhausen, J., Vogt, F. M., Buzug, T. M. and Lüdtke-Buzug, K.: Fundamentals and Potential of Magnetic Particle Imaging, Current Cardiovascular Imaging Reports, 6(5), 390-398, 2013, DOI: 10.1007/s12410-013-9217-1.
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  @article{Duschka2013d, author = {Duschka, Robert L. and Haegele, Julian and Panagiotopoulos, Nikolaos and Wojtczyk, Hanne and Barkhausen, Joerg and Vogt, Florian M. and Buzug, Thorsten M. and Lüdtke-Buzug, Kerstin}, journal = {Current Cardiovascular Imaging Reports}, keywords = {BuzugThorsten IMT LuedtkeKerstin MPI MedimaghHanne}, number = 5, pages = {390-398}, publisher = {Springer US}, title = {Fundamentals and Potential of Magnetic Particle Imaging}, volume = 6, year = 2013 }
• Graeser, M., Knopp, T., Grüttner, M., Sattel, T. F. and Buzug, T. M.: Analog receive signal processing for magnetic particle imaging, Medical Physics, 40(4), 042303, 2013, DOI: 10.1118/1.4794482.
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  @article{Graeser2013b, abstract = {Purpose: Magnetic particle imaging (MPI) applies oscillating magnetic fields to determine the distribution of magnetic nanoparticlesin vivo. Using a receive coil, the change of the particle magnetization can be detected. However, the signal induced by the nanoparticles is superimposed by the direct feedthrough interference of the sinusoidal excitation field, which couples into the receive coils. As the latter is several magnitudes higher, the extraction of the particle signal from the excitation signal is a challenging task. Methods: One way to remove the interfering signal is to suppress the excitation signal by means of a band-stop filter. However, this technique removes parts of the desired particle signal, which are essential for direct reconstruction of the particle concentration. A way to recover the entire particle signal is to cancel out the excitation signal by coupling a matching cancellation signal into the receive chain. However, the suppression rates that can be achieved by signal cancellation are not as high as with the filtering method, which limits the sensitivity of this method. In order to unite the advantages of both methods, in this work the authors propose to combine the filtering and the cancellation technique. All methods were compared by measuring 10 μl Resovist, in the same field generator only switching the signal processing parts. Results: The reconstructed time signals of the three methods, show the advantage of the proposed combination of filtering and cancellation. The method preserves the fundamental frequency and is able to detect the tracer signal at its full bandwidth even for low concentrations. Conclusions: By recovering the full particle signal the SNR can be improved and errors in the x-space reconstruction are prevented. The authors show that the combined method provides this full particle signal and makes it possible to improve image quality.}, author = {Graeser, Matthias and Knopp, Tobias and Grüttner, Mandy and Sattel, Timo F. and Buzug, Thorsten M.}, journal = {Medical Physics}, keywords = {AhlborgMandy BuzugThorsten GraeserMatthias IMT MAPIT MPS}, number = 4, pages = {042303}, title = {Analog receive signal processing for magnetic particle imaging}, volume = 40, year = 2013 }
• Gollmer, S. T. and Buzug, T. M.: Relaxed Statistical Shape Models for 3D Image Segmentation textendash Application to Mandible Bone in Cone-beam CT Data, Current Medical Imaging Reviews, 9(2), 129-137, 2013, DOI: 10.2174/1573405611309020008.
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  @article{Gollmer:2013a, author = {Gollmer, Sebastian T. and Buzug, Thorsten M.}, journal = {Current Medical Imaging Reviews}, keywords = {BuzugThorsten CT IMT}, month = {may}, number = 2, pages = {129-137}, publisher = {Bentham Science Publishers Ltd.}, title = {Relaxed Statistical Shape Models for 3D Image Segmentation {\textendash} Application to Mandible Bone in Cone-beam {CT} Data}, volume = 9, year = 2013 }
• Levakhina, Y. M., Müller, J., Duschka, R. L., Vogt, F., Barkhausen, J. and Buzug, T. M.: Weighted simultaneous algebraic reconstruction technique for tomosynthesis imaging of objects with high-attenuation features, Medical Physics, 40(3), 031106, 2013, DOI: 10.1118/1.4789592.
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  @article{levakhina:2013a, abstract = {Purpose: This paper introduces a nonlinear weighting scheme into the backprojection operation within the simultaneous algebraic reconstruction technique (SART). It is designed for tomosynthesis imaging of objects with high-attenuation features in order to reduce limited angle artifacts. Methods: The algorithm estimates which projections potentially produce artifacts in a voxel. The contribution of those projections into the updating term is reduced. In order to identify those projections automatically, a four-dimensional backprojected space representation is used. Weighting coefficients are calculated based on a dissimilarity measure, evaluated in this space. For each combination of an angular view direction and a voxel position an individual weighting coefficient for the updating term is calculated. Results: The feasibility of the proposed approach is shown based on reconstructions of the following real three-dimensional tomosynthesis datasets: a mammography quality phantom, an apple with metal needles, a dried finger bone in water, and a human hand. Datasets have been acquired with a Siemens Mammomat Inspiration tomosynthesis device and reconstructed using SART with and without suggested weighting. Out-of-focus artifacts are described using line profiles and measured using standard deviation (STD) in the plane and below the plane which contains artifact-causing features. Artifacts distribution in axial direction is measured using an artifact spread function (ASF). The volumes reconstructed with the weighting scheme demonstrate the reduction of out-of-focus artifacts, lower STD (meaning reduction of artifacts), and narrower ASF compared to nonweighted SART reconstruction. It is achieved successfully for different kinds of structures: point-like structures such as phantom features, long structures such as metal needles, and fine structures such as trabecular bone structures. Conclusions: Results indicate the feasibility of the proposed algorithm to reduce typical tomosynthesis artifacts produced by high-attenuation features. The proposed algorithm assigns weighting coefficients automatically and no segmentation or tissue-classification steps are required. The algorithm can be included into various iterative reconstruction algorithms with an additive updating strategy. It can also be extended to computed tomography case with the complete set of angular data.}, author = {Levakhina, Y. M. and Müller, J. and Duschka, R. L. and Vogt, F. and Barkhausen, J. and Buzug, T. M.}, journal = {Medical Physics}, keywords = {BuzugThorsten IMT}, number = 3, pages = {031106}, title = {Weighted simultaneous algebraic reconstruction technique for tomosynthesis imaging of objects with high-attenuation features}, volume = 40, year = 2013 }
• Erbe, M., Weber, M., Sattel, T. F. and Buzug, T. M.: Experimental Validation of an Assembly of Optimized Curved Rectangular Coils for the use in Dynamic Field Free Line Magnetic Particle Imaging, Current Medical Imaging Reviews, 9(2), 89-95, 2013, DOI: 10.2174/1573405611309020003.
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  @article{Erbe:2013a, author = {Erbe, M. and Weber, M. and Sattel, T. F. and Buzug, T. M.}, journal = {Current Medical Imaging Reviews}, keywords = {BuzugThorsten IMT LUMEN WeberMatthias}, number = 2, pages = {89-95}, title = {Experimental Validation of an Assembly of Optimized Curved Rectangular Coils for the use in Dynamic Field Free Line Magnetic Particle Imaging}, volume = 9, year = 2013 }
• Lüdtke-Buzug, K., Haegele, J., Biederer, S., Sattel, T. F., Erbe, M., Duschka, R. L., Barkhausen, J. and Vogt, F. M.: Comparison of commercial iron oxide-based MRI contrast agents with synthesized high-performance MPI tracers, Biomedizinische Technik / Biomedical Engineering, 58(6), 527-533, 2013, DOI: 10.1515/bmt-2012-0059.
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  @article{Luedtke-Buzug2013a, author = {Lüdtke-Buzug, Kerstin and Haegele, Julian and Biederer, Sven and Sattel, Timo F. and Erbe, Marlitt and Duschka, Robert L. and Barkhausen, Jörg and Vogt, Florian M.}, booktitle = {Biomedizinische Technik / Biomedical Engineering}, keywords = {BCE IMT LuedtkeKerstin}, number = 6, pages = {527-533}, title = {Comparison of commercial iron oxide-based MRI contrast agents with synthesized high-performance MPI tracers}, volume = 58, year = 2013 }
• Toma, A., Castillo, L. R. C., Schuetz, T. A., Becker, S., Mang, A., Regnier-Vigouroux, A. and Buzug, T. M.: A Validated Mathematical Model of Tumour-Immune Interactions for Glioblastoma, Current Medical Imaging Reviews, 9(2), 145-153, 2013, DOI: 10.2174/1573405611309020010.
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  @article{Toma_2013, author = {Toma, Alina and Castillo, Liliana R. Cisneros and Schuetz, Tina A. and Becker, Stefan and Mang, Andreas and Regnier-Vigouroux, Anne and Buzug, Thorsten M.}, journal = {Current Medical Imaging Reviews}, keywords = {BeckerStefan BuzugThorsten IMT}, month = {may}, number = 2, pages = {145-153}, publisher = {Bentham Science Publishers Ltd.}, title = {A Validated Mathematical Model of Tumour-Immune Interactions for Glioblastoma}, volume = 9, year = 2013 }
• Haegele, J., Biederer, S., Wojtczyk, H., Graeser, M., Knopp, T., Buzug, T. M., Barkhausen, J. and Vogt, F. M.: Toward cardiovascular interventions guided by magnetic particle imaging: First instrument characterization, Magnetic Resonance in Medicine, 69(6), 1761-1767, 2013, DOI: 10.1002/mrm.24421.
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  @article{Haegele2012j, abstract = {Magnetic particle imaging has emerged as a new technique for the visualization and quantification of superparamagnetic iron oxide nanoparticles. It seems to be a very promising application for cardiovascular interventional radiology. A prerequisite for interventions is the artifact-free visualization of the required instruments and implants. Various commercially available catheters, guide wires, and a catheter experimentally coated with superparamagnetic iron oxide nanoparticles were tested regarding their signal characteristics using magnetic particle spectroscopy to evaluate their performance in magnetic particle imaging. The results indicate that signal-generating and non-signal-generating instruments can be distinguished. Furthermore, coating or loading non-signal-generating instruments with superparamagnetic iron oxide nanoparticles seems to be a promising approach, but optimized nanoparticles need yet to be developed. Magn Reson Med, 2013. © 2012 Wiley Periodicals, Inc.}, author = {Haegele, Julian and Biederer, Sven and Wojtczyk, Hanne and Graeser, Matthias and Knopp, Tobias and Buzug, Thorsten M. and Barkhausen, Jörg and Vogt, Florian M.}, journal = {Magnetic Resonance in Medicine}, keywords = {BuzugThorsten GraeserMatthias IMT MedimaghHanne}, number = 6, pages = {1761-1767}, publisher = {Wiley Subscription Services, Inc., A Wiley Company}, title = {Toward cardiovascular interventions guided by magnetic particle imaging: First instrument characterization}, volume = 69, year = 2013 }
• Schuetz, T. A., Becker, S., Mang, A., Toma, A. and Buzug, T. M.: Modelling of glioblastoma growth by linking a molecular interaction network with an agent-based model, Mathematical and Computer Modelling of Dynamical Systems, 19(5), 417-433, 2013, DOI: 10.1080/13873954.2013.777748.
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  @article{Schuetz2013a, abstract = {In this work, a mathematical model of malignant brain tumour growth is presented. In particular, the growth of glioblastoma is investigated on the intracellular and intercellular scale. The Go or Grow principle of tumour cells states that tumour cells either migrate or proliferate. For glioblastoma, microRNA-451 has been shown to be an energy dependent key regulator of the LKB1 (liver kinase B1) and AMPK (AMP-activated protein kinase) pathway that influences the signalling for migration or cell division. We introduce a mathematical model that reproduces these biological processes. The intracellular molecular interaction network is represented by a system of nine ordinary differential equations. This is put into a multiscale context by applying an agent-based approach: each cell is equipped with this interaction network and additional rules to determine its new phenotype as either migrating, proliferating or quiescent. The evaluation of the proposed model by comparison of the results with in vitro experiments indicates its validity.}, author = {Schuetz, Tina A. and Becker, Stefan and Mang, Andreas and Toma, Alina and Buzug, Thorsten M.}, journal = {Mathematical and Computer Modelling of Dynamical Systems}, keywords = {BeckerStefan BuzugThorsten IMT}, number = 5, pages = {417-433}, title = {Modelling of glioblastoma growth by linking a molecular interaction network with an agent-based model}, volume = 19, year = 2013 }
• Kratz, B., Weyers, I. and Buzug, T. M.: A fully 3D approach for metal artifact reduction in computed tomography, Medical Physics, 39(11), 7042-7054, 2012, DOI: 10.1118/1.4762289.
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  @article{Kratz2012b, abstract = {Purpose: In computed tomographyimaging metal objects in the region of interest introduce inconsistencies during data acquisition. Reconstructing these data leads to an image in spatial domain including star-shaped or stripe-like artifacts. In order to enhance the quality of the resulting image the influence of the metal objects can be reduced. Here, a metal artifact reduction (MAR) approach is proposed that is based on a recomputation of the inconsistent projection data using a fully three-dimensional Fourier-based interpolation. The success of the projection space restoration depends sensitively on a sensible continuation of neighboring structures into the recomputed area. Fortunately, structural information of the entire data is inherently included in the Fourier space of the data. This can be used for a reasonable recomputation of the inconsistent projection data. Methods: The key step of the proposed MAR strategy is the recomputation of the inconsistent projection data based on an interpolation using nonequispaced fast Fourier transforms (NFFT). The NFFT interpolation can be applied in arbitrary dimension. The approach overcomes the problem of adequate neighborhood definitions on irregular grids, since this is inherently given through the usage of higher dimensional Fourier transforms. Here, applications up to the third interpolation dimension are presented and validated. Furthermore, prior knowledge may be included by an appropriate damping of the transform during the interpolation step. This MAR method is applicable on each angular view of a detector row, on two-dimensional projection data as well as on three-dimensional projection data, e.g., a set of sequential acquisitions at different spatial positions, projection data of a spiral acquisition, or cone-beam projection data. Results: Results of the novel MAR scheme based on one-, two-, and three-dimensional NFFT interpolations are presented. All results are compared in projection data space and spatial domain with the well-known one-dimensional linear interpolation strategy. Conclusions: In conclusion, it is recommended to include as much spatial information into the recomputation step as possible. This is realized by increasing the dimension of the NFFT. The resulting image quality can be enhanced considerably.}, author = {Kratz, Bärbel and Weyers, Imke and Buzug, Thorsten M.}, journal = {Medical Physics}, keywords = {BuzugThorsten IMT MetalArtefactReduction}, number = 11, pages = {7042-7054}, title = {A fully 3D approach for metal artifact reduction in computed tomography}, volume = 39, year = 2012 }
• Haegele, J., Sattel, T., Erbe, M., Lüdtke-Buzug, K., Taupitz, M., Borgert, J., Buzug, T. M., Barkhausen, J. and Vogt, F. M.: Magnetic Particle Imaging (MPI), RöFo: Fortschritte auf dem Gebiet der Röntgenstrahlen und bildgebenden Verfahren, 2012.
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  @article{Haegele2011a, author = {Haegele, J. and Sattel, T. and Erbe, M. and Lüdtke-Buzug, K. and Taupitz, M. and Borgert, J. and Buzug, T. M. and Barkhausen, J. and Vogt, F. M.}, journal = {RöFo: Fortschritte auf dem Gebiet der Röntgenstrahlen und bildgebenden Verfahren}, keywords = {BuzugThorsten IMT LuedtkeKerstin}, title = {Magnetic Particle Imaging (MPI)}, year = 2012 }
• Mang, A., Toma, A., Schuetz, T. A., Becker, S. and Buzug, T. M.: A Generic Framework for Modeling Brain Deformation as a Constrained Parametric Optimization Problem to Aid Non-diffeomorphic Image Registration in Brain Tumor Imaging, Methods of Information in Medicine, 51(5), 429-440, 2012, DOI: 10.3414/me11-02-0036.
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  @article{Mang:2012d, author = {Mang, A. and Toma, A. and Schuetz, T. A. and Becker, S. and Buzug, T. M.}, journal = {Methods of Information in Medicine}, keywords = {BeckerStefan BuzugThorsten IMT}, month = {oct}, number = 5, pages = {429-440}, publisher = {Schattauer {GmbH}}, title = {A Generic Framework for Modeling Brain Deformation as a Constrained Parametric Optimization Problem to Aid Non-diffeomorphic Image Registration in Brain Tumor Imaging}, volume = 51, year = 2012 }
• Mang, A., Schuetz, T. A., Becker, S., Toma, A. and Buzug, T. M.: Cyclic Numerical Time Integration in Variational Non-Rigid Image Registration based on Quadratic Regularisation, Vision, Modeling and Visualization, 143-150, 2012, DOI: 10.2312/PE/VMV/VMV12/143-150.
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  @article{e797aadc-ed38-43ab-af47-d6fa2b67eb4c, author = {Mang, A. and Schuetz, T. A. and Becker, S. and Toma, A. and Buzug, T.M.}, booktitle = {Vision, Modeling and Visualization}, keywords = {BeckerStefan BuzugThorsten IMT}, pages = {143-150}, publisher = {The Eurographics Association}, title = {Cyclic Numerical Time Integration in Variational Non-Rigid Image Registration based on Quadratic Regularisation}, year = 2012 }
• Haegele, J., Rahmer, J., Gleich, B., Borgert, J., Wojtczyk, H., Panagiotopoulos, N., Buzug, T. M., Barkhausen, J. and Vogt, F. M.: Magnetic Particle Imaging: Visualization of Instruments for Cardiovascular Intervention, Radiology, 265(3), 933-938, 2012, DOI: 10.1148/radiol.12120424.
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  @article{Haegele2012i, author = {Haegele, Julian and Rahmer, Jürgen and Gleich, Bernhard and Borgert, Jörn and Wojtczyk, Hanne and Panagiotopoulos, Nikolaos and Buzug, Thorsten M. and Barkhausen, Jörg and Vogt, Florian M.}, journal = {Radiology}, keywords = {BuzugThorsten IMT MedimaghHanne}, month = {dec}, number = 3, pages = {933-938}, publisher = {Radiological Society of North America ({RSNA})}, title = {Magnetic Particle Imaging: Visualization of Instruments for Cardiovascular Intervention}, volume = 265, year = 2012 }
• Buzug, T. M., Bringout, G., Erbe, M., Gräfe, K., Graeser, M., Grüttner, M., Halkola, A., Sattel, T. F., Tenner, W., Wojtczyk, H., Haegele, J., Vogt, F. M., Barkhausen, J. and Lüdtke-Buzug, K.: Magnetic particle imaging: Introduction to imaging and hardware realization, Zeitschrift für Medizinische Physik, 22(4), 323-334, 2012, DOI: 10.1016/j.zemedi.2012.07.004.
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  @article{Buzug2012b, abstract = {Magnetic Particle Imaging (MPI) is a recently invented tomographic imaging method that quantitatively measures the spatial distribution of a tracer based on magnetic nanoparticles. The new modality promises a high sensitivity and high spatial as well as temporal resolution. There is a high potential of \{MPI\} to improve interventional and image-guided surgical procedures because, today, established medical imaging modalities typically excel in only one or two of these important imaging properties. \{MPI\} makes use of the non-linear magnetization characteristics of the magnetic nanoparticles. For this purpose, two magnetic fields are created and superimposed, a static selection field and an oscillatory drive field. If superparamagnetic iron-oxide nanoparticles (SPIOs) are subjected to the oscillatory magnetic field, the particles will react with a non-linear magnetization response, which can be measured with an appropriate pick-up coil arrangement. Due to the non-linearity of the particle magnetization, the received signal consists of the fundamental excitation frequency as well as of harmonics. After separation of the fundamental signal, the nanoparticle concentration can be reconstructed quantitatively based on the harmonics. The spatial coding is realized with the static selection field that produces a field-free point, which is moved through the field of view by the drive fields. This article focuses on the frequency-based image reconstruction approach and the corresponding imaging devices while alternative concepts like x-space \{MPI\} and field-free line imaging are described as well. The status quo in hardware realization is summarized in an overview of \{MPI\} scanners.}, author = {Buzug, T.M. and Bringout, G. and Erbe, M. and Gräfe, K. and Graeser, M. and Grüttner, M. and Halkola, A. and Sattel, T.F. and Tenner, W. and Wojtczyk, H. and Haegele, J. and Vogt, F.M. and Barkhausen, J. and Lüdtke-Buzug, K.}, journal = {Zeitschrift für Medizinische Physik}, keywords = {AhlborgMandy BringoutGael BuzugThorsten GraefeKsenija GraeserMatthias IMT LuedtkeKerstin MedimaghHanne}, note = {Schwerpunkt: Multimodale Bildgebung und Therapie}, number = 4, pages = {323-334}, title = {Magnetic particle imaging: Introduction to imaging and hardware realization}, volume = 22, year = 2012 }
• Toma, A., Mang, A., Schuetz, T. A., Becker, S. and Buzug, T. M.: A Novel Method for Simulating the Extracellular Matrix in Models of Tumour Growth, Computational and Mathematical Methods in Medicine, 2012, 109019, 2012, DOI: 10.1155/2012/109019.
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  @article{Toma:2012e, author = {Toma, Alina and Mang, Andreas and Schuetz, Tina A. and Becker, Stefan and Buzug, Thorsten M.}, journal = {Computational and Mathematical Methods in Medicine}, keywords = {BeckerStefan BuzugThorsten IMT}, pages = 109019, title = {A Novel Method for Simulating the Extracellular Matrix in Models of Tumour Growth}, volume = 2012, year = 2012 }
• Mang, A., Toma, A., Schuetz, T. A., Becker, S., Eckey, T., Mohr, C., Petersen, D. and Buzug, T. M.: Biophysical modeling of brain tumor progression: From unconditionally stable explicit time integration to an inverse problem with parabolic PDE constraints for model calibration, Medical Physics, 39(7), 4444-4459, 2012, DOI: 10.1118/1.4722749.
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  @article{Mang:2012e, abstract = {Purpose: A novel unconditionally stable, explicit numerical method is introduced to the field of modelingbraincancer progression on a tissue level together with an inverse problem (IP) based on optimal control theory that allows for automated modelcalibration with respect to observations in clinical imaging data. Methods: Biophysical models of cancer progression on a tissue level are in general based on the assumption that the spatiotemporal spread of cancerous cells is determined by cell division and net migration. These processes are typically described in terms of a parabolic partial differential equation (PDE). In the present work a parallelized implementation of an unconditionally stable, explicit Euler (EE⋆) time integration method for the solution of this PDE is detailed. The key idea of the discussed EE⋆ method is to relax the strong stability requirement on the spectral radius of the coefficient matrix by introducing a subdivision regime for a given outer time step. The performance is related to common implicit numerical methods. To quantify the numerical error, a simplified model that has a closed form solution is considered. To allow for a systematic, phenomenological validation a novel approach for automated modelcalibration on the basis of observations in medical imaging data is developed. The resulting IP is based on optimal control theory and manifests as a large scale, PDE constrained optimization problem. Results: The numerical error of the EE⋆ method is at the order of standard implicit numerical methods. The computing times are well below those obtained for implicit methods and by that demonstrate efficiency. Qualitative and quantitative analysis in 12 patients demonstrates that the obtained results are in strong agreement with observations in medical imaging data. Rating simulation success in terms of the mean overlap between model predictions and manual expert segmentations yields a success rate of 75% (9 out of 12 patients). Conclusions: The discussed EE⋆ method provides desirable features for image-basedmodelcalibration or hybrid image registration algorithms in which the model serves as a biophysical prior. This is due to (i) ease of implementation, (ii) low memory requirements, (iii) efficiency, (iv) a straightforward interface for parameter updates, and (v) the fact that the method is inherently matrix-free. The explicit time integration method is confirmed via experiments for automated modelcalibration. Qualitative and quantitative analysis demonstrates that the proposed framework allows for recovering observations in medical imaging data and by that phenomenological model validity.}, author = {Mang, Andreas and Toma, Alina and Schuetz, Tina A. and Becker, Stefan and Eckey, Thomas and Mohr, Christian and Petersen, Dirk and Buzug, Thorsten M.}, journal = {Medical Physics}, keywords = {BeckerStefan BuzugThorsten IMT}, number = 7, pages = {4444-4459}, title = {Biophysical modeling of brain tumor progression: From unconditionally stable explicit time integration to an inverse problem with parabolic PDE constraints for model calibration}, volume = 39, year = 2012 }
• Knopp, T., Sattel, T. F. and Buzug, T. M.: Efficient Magnetic Gradient Field Generation With Arbitrary Axial Displacement for Magnetic Particle Imaging, IEEE Magnetic Letters, 3, 6500104, 2012, DOI: 10.1109/LMAG.2011.2181341.
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  @article{Knopp2012a, abstract = {The magnetic particle imaging method applies a magnetic gradient field featuring a field-free point (FFP) to determine the spatial distribution of superparamagnetic nanoparticles. Such a field is generated by two opposing electromagnetic coils, carrying currents in opposite directions. To achieve a large field of view, the FFP needs to be shifted in space. This can be realized by superimposing currents flowing in the same direction in both coils. For large displacements, the power loss increases drastically. In this letter, a new coil geometry is proposed, which is considerably more efficient for generating an FFP at off-center positions. It consists of four coils in which the currents are optimized to generate the required field at minimal power loss.}, author = {Knopp, T. and Sattel, T.F. and Buzug, T.M.}, journal = {IEEE Magnetic Letters}, keywords = {BuzugThorsten IMT}, pages = 6500104, title = {Efficient Magnetic Gradient Field Generation With Arbitrary Axial Displacement for Magnetic Particle Imaging}, volume = 3, year = 2012 }
• Schierp, F., Gollmer, S. T., Bischof, A., Buzug, T. M., Lücke, A., Barkhausen, J. and Simon, M.: Geometrische Basisanalyse der Leber und Milz als Referenzmodell für pathologische Formanalysen und automatische Organsegmentierung, RöFo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 183(S 01), 2011, DOI: 10.1055/s-0031-1279207.
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  @article{Schierp_2011, author = {Schierp, F and Gollmer, ST and Bischof, A and Buzug, TM and Lücke, A and Barkhausen, J and Simon, M}, journal = {RöFo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren}, keywords = {BuzugThorsten IMT}, month = {apr}, number = {S 01}, publisher = {Thieme Publishing Group}, title = {Geometrische Basisanalyse der Leber und Milz als Referenzmodell für pathologische Formanalysen und automatische Organsegmentierung}, volume = 183, year = 2011 }
• Knopp, T., Erbe, M., Sattel, T. F., Biederer, S. and Buzug, T. M.: A Fourier slice theorem for magnetic particle imaging using a field-free line, Inverse Problems, 27(9), 095004, 2011, DOI: 10.1088/0266-5611/27/9/095004.
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  @article{0266-5611-27-9-095004, abstract = {The magnetic particle imaging method is capable of imaging the distribution of magnetic nanoparticles in vivo . The sensitivity of the method can be significantly improved using a signal encoding scheme, which applies a field-free line (FFL) instead of the commonly used field-free point (FFP). Recent efforts have considerably improved the efficiency of the coil topology used to generate the FFL. However, until now it has not been investigated how the reconstruction of the particle distribution can be efficiently carried out when using the FFL encoding scheme. In this work, it is shown that the induced signal is linked to the Radon transform of the particle distribution. Hence, a fast algorithm for the reconstruction of the particle distribution can be derived, which first transforms the induced signal into Radon space and second applies a common reconstruction algorithm to transform the Radon data into image space.}, author = {Knopp, T and Erbe, M and Sattel, T F and Biederer, S and Buzug, T M}, journal = {Inverse Problems}, keywords = {BuzugThorsten IMT}, number = 9, pages = {095004}, title = {A Fourier slice theorem for magnetic particle imaging using a field-free line}, volume = 27, year = 2011 }
• Erbe, M., Knopp, T., Sattel, T. F., Biederer, S. and Buzug, T. M.: Experimental generation of an arbitrarily rotated field-free line for the use in magnetic particle imaging, Medical Physics, 38(9), 5200-5207, 2011, DOI: 10.1118/1.3626481.
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  @article{Erbe2010c, abstract = {Purpose: The concept of a magnetic field-free line (FFL), with regard to the novel tomographic modality magnetic particle imaging (MPI), was recently introduced. Theoretical approaches predict the improvement of sensitivity of MPI by a factor of ten replacing the conventionally used field-free point (FFP) by a FFL. In this work, an experimental apparatus for generating an arbitrarily rotated and translated FFL field is described and tested. Methods: A theoretical motivation for the implemented setup is provided and the required currents are derived in dependency of the coil sensitivities. A prototype of a FFL field generator is manufactured and the fields are measured using a Hall effect sensor. An evaluation of the generated fields is performed via comparison to simulated data. Results: To utilize the FFL concept for MPI, the setup generating the fields needs to be feasible in praxis with respect to power loss. Furthermore, rotating and translating the FFL, while keeping the setup static in space, is a crucial aspect for conveying FFL imaging to clinical applications. The implemented setup copes with both of these challenges and allows for experimental generation as well as evaluation of the required fields. The generated fields agree to within 3.5% of model predictions. Conclusions: This work transfers the FFL concept from theoretical considerations to the implementation of an experimental setup generating the required fields. The high agreement of the measured fields with simulated data indicates the feasibility of magnetic field generation for the implementation of FFL imaging in MPI.}, author = {Erbe, Marlitt and Knopp, Tobias and Sattel, Timo F. and Biederer, Sven and Buzug, Thorsten M.}, journal = {Medical Physics}, keywords = {BuzugThorsten IMT}, number = 9, pages = {5200-5207}, title = {Experimental generation of an arbitrarily rotated field-free line for the use in magnetic particle imaging}, volume = 38, year = 2011 }
• Knopp, T., Biederer, S., Sattel, T. F., Erbe, M. and Buzug, T. M.: Prediction of the Spatial Resolution of Magnetic Particle Imaging Using the Modulation Transfer Function of the Imaging Process, IEEE Transactions on Medical Imaging, 30(6), 1284-1292, 2011, DOI: 10.1109/TMI.2011.2113188.
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  @article{Knopp2011c, abstract = {The magnetic particle imaging method allows for the quantitative determination of spatial distributions of superparamagnetic nanoparticles in vivo. Recently, it was shown that the 1-D magnetic particle imaging process can be formulated as a convolution. Analyzing the width of the convolution kernel allows for predicting the spatial resolution of the method. However, this measure does not take into account the noise of the measured data. Furthermore, it does not consider a reconstruction step, which can increase the resolution beyond the width of the convolution kernel. In this paper, the spatial resolution of magnetic particle imaging is investigated by analyzing the modulation transfer function of the imaging process. An expression for the spatial resolution is derived, which includes the noise level and which is validated in simulations and experiments.}, author = {Knopp, T. and Biederer, S. and Sattel, T.F. and Erbe, M. and Buzug, T.M.}, journal = {IEEE Transactions on Medical Imaging}, keywords = {BuzugThorsten IMT}, month = {June}, number = 6, pages = {1284-1292}, title = {Prediction of the Spatial Resolution of Magnetic Particle Imaging Using the Modulation Transfer Function of the Imaging Process}, volume = 30, year = 2011 }
• Erbe, M., Sattel, T. F., Knopp, T., Biederer, S. and Buzug, T. M.: An optimized field free line scanning device for magnetic particle imaging, Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung, 56(Suppl. 1), 2011.
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  @article{Erbe:2011b, author = {Erbe, M. and Sattel, T. F. and Knopp, T. and Biederer, S. and Buzug, T. M.}, journal = {Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung}, keywords = {BuzugThorsten IMT}, number = {Suppl. 1}, title = {An optimized field free line scanning device for magnetic particle imaging}, volume = 56, year = 2011 }
• Kratz, B., Ens, S., Müller, J. and Buzug, T. M.: Reference-free ground truth metric for metal artifact evaluation in CT images, Medical Physics, 38(7), 4321-4328, 2011, DOI: 10.1118/1.3603198.
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  @article{Kratz2011a, abstract = {Purpose: In computed tomography(CT), metal objects in the region of interest introduce data inconsistencies during acquisition. Reconstructing these data results in an image with star shaped artifacts induced by the metal inconsistencies. To enhance image quality, the influence of the metal objects can be reduced by different metal artifact reduction (MAR) strategies. For an adequate evaluation of new MAR approaches a ground truth reference data set is needed. In technical evaluations, where phantoms can be measured with and without metal inserts, ground truth data can easily be obtained by a second reference data acquisition. Obviously, this is not possible for clinical data. Here, an alternative evaluation method is presented without the need of an additionally acquired reference data set. Methods: The proposed metric is based on an inherent ground truth for metal artifacts as well as MAR methods comparison, where no reference information in terms of a second acquisition is needed. The method is based on the forward projection of a reconstructed image, which is compared to the actually measured projection data. Results: The new evaluation technique is performed on phantom and on clinical CT data with and without MAR. The metric results are then compared with methods using a reference data set as well as an expert-based classification. It is shown that the new approach is an adequate quantification technique for artifact strength in reconstructed metal or MAR CTimages. Conclusions: The presented method works solely on the original projection data itself, which yields some advantages compared to distance measures in image domain using two data sets. Beside this, no parameters have to be manually chosen. The new metric is a useful evaluation alternative when no reference data are available.}, author = {Kratz, Bärbel and Ens, Svitlana and Müller, Jan and Buzug, Thorsten M.}, journal = {Medical Physics}, keywords = {BuzugThorsten IMT MetalArtefactReduction}, number = 7, pages = {4321-4328}, title = {Reference-free ground truth metric for metal artifact evaluation in CT images}, volume = 38, year = 2011 }
• Knopp, T., Biederer, S., Sattel, T. F., Rahmer, J., Weizenecker, J., Gleich, B., Borgert, J. and Buzug, T. M.: 2D model-based reconstruction for magnetic particle imaging, Medical Physics, 37(2), 485-491, 2010, DOI: 10.1118/1.3271258.
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  @article{Knopp2010b, abstract = {Purpose: Magnetic particle imaging (MPI) is a new quantitative imaging technique capable of determining the spatial distribution of superparamagnetic nanoparticles at high temporal and spatial resolution. For reconstructing this spatial distribution, the particle dynamics and the scanner properties have to be known. To date, they are obtained in a tedious calibration procedure by measuring the magnetization response of a small delta sample shifted through the measuring field. Recently, first reconstruction results using a 1D model-based system function were published, showing comparable image quality as obtained with a measured system function. In this work, first 2D model-based reconstruction results of measured MPI data are presented. Methods: To simulate the system function, various parameters have to be modeled, namely, the magnetic field, the particle magnetization, the voltage induced in the receive coils, and the transfer function of the receive chain. To study the accuracy of the model-based approach, 2D MPI data are measured and reconstructed with modeled and measured system functions. Results: It is found that the model-based system function is sufficiently accurate to allow for reconstructing experimental data. The resulting image quality is close to that obtained with a measurement-basedreconstruction. Conclusions: The model-based system function approach addresses a major drawback of the measurement-based procedure, namely, the long acquisition time. In this work, the acquisition of the measurement-based system function took 45 min , while the model-based system function was obtained in only 15 s . For 3D data, where the acquisition of the measurement-based system function takes more than 6 h , the need for an efficient system function generation is even more obvious.}, author = {Knopp, Tobias and Biederer, Sven and Sattel, Timo F. and Rahmer, Jürgen and Weizenecker, Jürgen and Gleich, Bernhard and Borgert, Jörn and Buzug, Thorsten M.}, journal = {Medical Physics}, keywords = {BuzugThorsten IMT}, number = 2, pages = {485-491}, title = {2D model-based reconstruction for magnetic particle imaging}, volume = 37, year = 2010 }
• Knopp, T., Sattel, T. F. and Buzug, S. B. T. M.: Field-Free line formation in a magnetic field, Journal of Physics A: Mathematical and Theoretical, 43(1), 9pp, 2010, DOI: 10.1088/1751-8113/43/1/012002.
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  @article{Knopp2010d, author = {Knopp, T. and Sattel, {T. F.} and Buzug, S. Biederer {T. M.}}, journal = {Journal of Physics A: Mathematical and Theoretical}, keywords = {BuzugThorsten IMT}, number = 1, pages = {9pp}, title = {Field-Free line formation in a magnetic field}, volume = 43, year = 2010 }
• Knopp, T., Erbe, M., Biederer, S., Sattel, T. F. and Buzug, T. M.: Efficient generation of a magnetic field-free line, Medical Physics, 37(7), 3538-3540, 2010, DOI: 10.1118/1.3447726.
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  @article{Knopp2010h, abstract = {Purpose: Signal encoding in magnetic particle imaging (MPI) is achieved by moving a field-free point (FFP) through the region of interest. One way to increase the sensitivity of the method is to scan the region of interest with a field-free line (FFL) instead of the FFP. Recently, the first feasible FFL coil setup was introduced. The purpose of this article is to improve the efficiency of the FFL coil geometry even further. Methods: In order to reduce the electrical power loss of the setup, an additional Maxwellcoil pair is introduced that is tailored to generate the static part of the FFL field. Results: Using the proposed coil assembly, the electrical power loss for the generation of a rotating FFL is considerably reduced compared to previously known coil setups. Furthermore, the quality of the generated FFL is significantly increased. Conclusions: The proposed coil assembly is almost as efficient as an equivalent FFP scanner. Furthermore, the assembly cannot only be used for FFL imaging but for FFP imaging as well. Hence, the findings of this article denote an important step toward the first practical implementation of the FFL coil geometry.}, author = {Knopp, Tobias and Erbe, Marlitt and Biederer, Sven and Sattel, Timo F. and Buzug, Thorsten M.}, journal = {Medical Physics}, keywords = {BuzugThorsten IMT}, number = 7, pages = {3538-3540}, title = {Efficient generation of a magnetic field-free line}, volume = 37, year = 2010 }
• Knopp, T., Sattel, T. F., Biederer, S., Rahmer, J., Weizenecker, J., Gleich, B., Borgert, J. and Buzug, T. M.: Model-Based Reconstruction for Magnetic Particle Imaging, IEEE Transactions on Medical Imaging, 29(1), 12-18, 2010, DOI: 10.1109/TMI.2009.2021612.
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  @article{Knopp2009c, abstract = {Magnetic particle imaging (MPI) is a new imaging modality capable of imaging distributions of superparamagnetic nanoparticles with high sensitivity, high spatial resolution and, in particular, high imaging speed. The image reconstruction process requires a system function, describing the mapping between particle distribution and acquired signal. To date, the system function is acquired in a tedious calibration procedure by sequentially measuring the signal of a delta sample at the positions of a grid that covers the field of view. In this work, for the first time, the system function is calculated using a model of the signal chain. The modeled system function allows for reconstruction of the particle distribution in a 1-D MPI experiment. The approach thus enables fast generation of system functions on arbitrarily dense grids. Furthermore, reduction in memory requirements may be feasible by generating parts of the system function on the fly during reconstruction instead of keeping the complete matrix in memory.}, author = {Knopp, T. and Sattel, T.F. and Biederer, S. and Rahmer, J. and Weizenecker, J. and Gleich, B. and Borgert, J. and Buzug, T.M.}, journal = {IEEE Transactions on Medical Imaging}, keywords = {BuzugThorsten IMT}, month = {jan}, number = 1, pages = {12-18}, title = {Model-Based Reconstruction for Magnetic Particle Imaging}, volume = 29, year = 2010 }
• Knopp, T., Erbe, M., Sattel, T. F., Biederer, S. and Buzug, T. M.: Generation of a static magnetic field-free line using two Maxwell coil pairs, Applied Physics Letters, 97(9), 2010, DOI: 10.1063/1.3486118.
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  @article{Knopp2010i, abstract = {In this paper, the generation of a magnetic field-free line (FFL) along a constant direction is investigated. It is shown that an FFL gradient field can be generated by two perpendicular Maxwell coil pairs. These coils can be used for imaging distributions of superparamagnetic nanoparticles with high sensitivity applying the magnetic particle imaging technique. To this end, the FFL has to be rapidly moved back and forth while either the object or the coil assembly rotates slowly. The field quality of the proposed coil setup is assessed by manufacturing a prototype and measuring the magnetic field using a Hall-effect sensor.}, author = {Knopp, Tobias and Erbe, Marlitt and Sattel, Timo F. and Biederer, Sven and Buzug, Thorsten M.}, journal = {Applied Physics Letters}, keywords = {BuzugThorsten IMT}, number = 9, title = {Generation of a static magnetic field-free line using two Maxwell coil pairs}, volume = 97, year = 2010 }
• Buzug, T. M., Sattel, T. F., Erbe, M., Biederer, S., Borgert, J., Finas, D., Dietrich, K., Vogt, F., Barkhausen, J., Lüdtke-Buzug, K. and Knopp, T.: Alternative Spulentopologien für Magnetic-Particle-Imaging, RöFo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 182(11), A56, 2010, DOI: 10.1055/s-0030-1268341.
  [ BibTeX ] [ URL ]
   
  @article{Buzug_2010, author = {Buzug, TM and Sattel, TF and Erbe, M and Biederer, S and Borgert, J and Finas, D and Dietrich, K and Vogt, F and Barkhausen, J and Lüdtke-Buzug, K and Knopp, T}, journal = {RöFo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren}, keywords = {BuzugThorsten IMT LuedtkeKerstin}, month = {nov}, number = 11, pages = {A56}, publisher = {Thieme Publishing Group}, title = {Alternative Spulentopologien für Magnetic-Particle-Imaging}, volume = 182, year = 2010 }
• Lindemann, A., Lüdtke-Buzug, K., Hüsing, B., Pries, R., Buzug, T. M. and Wollenberg, B.: Nanoparticel labelling of stem cell populations in head and neck cancer, Journal of Stem Cells and Regenerative Medicine, 6(2), 143, 2010.
  [ BibTeX ]
   
  @article{Lindemann2010a, author = {Lindemann, A. and Lüdtke-Buzug, K. and Hüsing, B. and Pries, R. and Buzug, T.M. and Wollenberg, B.}, booktitle = {Journal of Stem Cells and Regenerative Medicine}, keywords = {BuzugThorsten IMT LuedtkeKerstin}, number = 2, pages = 143, title = {Nanoparticel labelling of stem cell populations in head and neck cancer}, volume = 6, year = 2010 }
• Knopp, T., Rahmer, J., Sattel, T. F., Biederer, S., Weizenecker, J., Gleich, B., Borgert, J. and Buzug, T. M.: Weighted iterative reconstruction for magnetic particle imaging, Physics in Medicine and Biology, 55(6), 1577, 2010, DOI: 10.1088/0031-9155/55/6/003.
  [ BibTeX ] [ URL ]
   
  @article{0031-9155-55-6-003, abstract = {Magnetic particle imaging (MPI) is a new imaging technique capable of imaging the distribution of superparamagnetic particles at high spatial and temporal resolution. For the reconstruction of the particle distribution, a system of linear equations has to be solved. The mathematical solution to this linear system can be obtained using a least-squares approach. In this paper, it is shown that the quality of the least-squares solution can be improved by incorporating a weighting matrix using the reciprocal of the matrix-row energy as weights. A further benefit of this weighting is that iterative algorithms, such as the conjugate gradient method, converge rapidly yielding the same image quality as obtained by singular value decomposition in only a few iterations. Thus, the weighting strategy in combination with the conjugate gradient method improves the image quality and substantially shortens the reconstruction time. The performance of weighting strategy and reconstruction algorithms is assessed with experimental data of a 2D MPI scanner.}, author = {Knopp, T and Rahmer, J and Sattel, T F and Biederer, S and Weizenecker, J and Gleich, B and Borgert, J and Buzug, T M}, journal = {Physics in Medicine and Biology}, keywords = {BuzugThorsten IMT}, number = 6, pages = 1577, title = {Weighted iterative reconstruction for magnetic particle imaging}, volume = 55, year = 2010 }
• Vogt, F. M., Biederer, S., Simon, M., Lüdtke-Buzug, K., Knopp, T., Sattel, T. F., Buzug, T. M. and Barkhausen, J.: Magnetic Particle Imaging: Evaluation unterschiedlicher superparamagnetischer Eisenoxidpartikel für ein neues bildgebendes Verfahren, RöFo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 182(S 01), 2010, DOI: 10.1055/s-0030-1252832.
  [ BibTeX ] [ URL ]
   
  @article{Vogt2010c, author = {Vogt, FM and Biederer, S and Simon, M and Lüdtke-Buzug, K and Knopp, T and Sattel, TF and Buzug, TM and Barkhausen, J}, journal = {RöFo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren}, keywords = {BuzugThorsten IMT LuedtkeKerstin}, month = {mar}, number = {S 01}, publisher = {Thieme Publishing Group}, title = {Magnetic Particle Imaging: Evaluation unterschiedlicher superparamagnetischer Eisenoxidpartikel für ein neues bildgebendes Verfahren}, volume = 182, year = 2010 }
• Biederer, S., Knopp, T., Sattel, T. F., Lüdtke-Buzug, K., Gleich, B., Weizenecker, J., Borgert, J. and Buzug, T. M.: Magnetization response spectroscopy of superparamagnetic nanoparticles for magnetic particle imaging, Journal of Physics D: Applied Physics, 42(20), 205007, 2009, DOI: 10.1088/0022-3727/42/20/205007.
  [ BibTeX ] [ URL ]
   
  @article{Biederer2009d, abstract = {Magnetic particle imaging (MPI) is a tomographic imaging modality sensitive to the spatial distribution of magnetic particles. The spectrometer, described in this paper, is capable of measuring the remagnetization spectrum of superparamagnetic nanoparticles. With this spectrometer the suitability of particles, for MPI, can be characterized. Furthermore, the spectrometer can be used to estimate the particle size distribution, which allows for more accurate simulations in MPI.}, author = {Biederer, S and Knopp, T and Sattel, T F and Lüdtke-Buzug, K and Gleich, B and Weizenecker, J and Borgert, J and Buzug, T M}, journal = {Journal of Physics D: Applied Physics}, keywords = {BuzugThorsten IMT LuedtkeKerstin MPS}, number = 20, pages = 205007, title = {Magnetization response spectroscopy of superparamagnetic nanoparticles for magnetic particle imaging}, volume = 42, year = 2009 }
• Knopp, T., Biederer, S., Sattel, T., Weizenecker, J., Gleich, B., Borgert, J. and Buzug, T. M.: Trajectory analysis for magnetic particle imaging, Physics in Medicine and Biology, 54(2), 385, 2009.
  [ BibTeX ] [ URL ]
   
  @article{Knopp2009a, abstract = {Recently a new imaging technique called magnetic particle imaging was proposed. The method uses the nonlinear response of magnetic nanoparticles when a time varying magnetic field is applied. Spatial encoding is achieved by moving a field-free point through an object of interest while the field strength in the vicinity of the point is high. A resolution in the submillimeter range is provided even for fast data acquisition sequences. In this paper, a simulation study is performed on different trajectories moving the field-free point through the field of view. The purpose is to provide mandatory information for the design of a magnetic particle imaging scanner. Trajectories are compared with respect to density, speed and image quality when applied in data acquisition. Since simulation of the involved physics is a time demanding task, moreover, an efficient implementation is presented utilizing caching techniques.}, author = {Knopp, T and Biederer, S and Sattel, T and Weizenecker, J and Gleich, B and Borgert, J and Buzug, T M}, journal = {Physics in Medicine and Biology}, keywords = {BuzugThorsten IMT}, number = 2, pages = 385, title = {Trajectory analysis for magnetic particle imaging}, volume = 54, year = 2009 }
• Mang, A., Schnabel, J. A., Crum, W. R., Modat, M., Camara-Rey, O., Palm, C., Caseiras, G. B., Jäger, H. R., Ourselin, S., Buzug, T. M. and Hawkes, D. J.: Consistency of parametric registration in serial MRI studies of brain tumor progression, Computer Assisted Radiology and Surgery, 3(3-4), 201-211, 2008, DOI: 10.1007/s11548-008-0234-5.
  [ BibTeX ] [ URL ]
   
  @article{noKey, author = {Mang, Andreas and Schnabel, JuliaA. and Crum, WilliamR. and Modat, Marc and Camara-Rey, Oscar and Palm, Christoph and Caseiras, GiseleBrasil and Jäger, H.Rolf and Ourselin, Sébastien and Buzug, ThorstenM. and Hawkes, DavidJ.}, journal = {Computer Assisted Radiology and Surgery}, keywords = {BuzugThorsten IMT}, number = {3-4}, pages = {201-211}, publisher = {Springer-Verlag}, title = {Consistency of parametric registration in serial MRI studies of brain tumor progression}, volume = 3, year = 2008 }
• Scheer, M., Arnold, S., Neugebauer, J., Ulrich, H., Buzug, T. M., Addicks, K. and Zoeller, J. E.: Reconstruction of Bony Defects in Rats with Pulp Derived Stem Cells, Journal of Cranio-Maxillofacial Surgery, 36, 157-158, 2008.
  [ BibTeX ]
   
  @article{Scheer2008a, author = {Scheer, M. and Arnold, S. and Neugebauer, J. and Ulrich, H. and Buzug, T. M. and Addicks, K. and Zoeller, J. E.}, journal = {Journal of Cranio-Maxillofacial Surgery}, keywords = {BuzugThorsten IMT}, pages = {157-158}, title = {Reconstruction of Bony Defects in Rats with Pulp Derived Stem Cells}, volume = 36, year = 2008 }
• Brinks, R. and Buzug, T. M.: Image reconstruction in positron emission tomography (PET): The 90th anniversary of Radon’s solution, Biomedical Engineering / Biomedizinische Technik, 52, 361-364, 2007, DOI: 10.1515/BMT.2007.060.
  [ BibTeX ] [ URL ]
   
  @article{Brinks2007a, author = {Brinks, Ralph and Buzug, T.M.}, journal = {Biomedical Engineering / Biomedizinische Technik}, keywords = {BuzugThorsten IMT}, pages = {361-364}, title = {Image reconstruction in positron emission tomography (PET): The 90th anniversary of Radon’s solution}, volume = 52, year = 2007 }
• J. Orschiedt, F. G. and Buzug, T. M.: Virtuelle Rekonstruktion und stereolithographisches Modell eines jungneolithischen Schädelfundes aus der Blätterhöhle in Hagen, Nordrhein-Westfalen, Archäologische Informationen, 30(1), 35-41, 2007, DOI: 10.11588/ai.2007.1.11152.
  [ BibTeX ] [ URL ]
   
  @article{Orschiedt2007, author = {J. Orschiedt, F. Gröning and Buzug, T. M.}, journal = {Archäologische Informationen}, keywords = {BuzugThorsten IMT NDT Neandertaler}, number = 1, pages = {35-41}, title = {Virtuelle Rekonstruktion und stereolithographisches Modell eines jungneolithischen Schädelfundes aus der Blätterhöhle in Hagen, Nordrhein-Westfalen}, volume = 30, year = 2007 }
• Oehler, M. and Buzug, T. M.: Two Step MLEM Algorithm for Artefact Reduction in CT Images, Computer Assisted Radiology and Surgery, 2(1:1), 38-41, 2007, DOI: 10.1007/s11548-007-0082-8.
  [ BibTeX ] [ URL ]
   
  @article{Oehler2007c, author = {Oehler, M. and Buzug, T. M.}, journal = {Computer Assisted Radiology and Surgery}, keywords = {BuzugThorsten IMT MetalArtefactReduction}, number = {1:1}, pages = {38-41}, title = {Two Step MLEM Algorithm for Artefact Reduction in CT Images}, volume = 2, year = 2007 }
• Buzug, T. and Oehler, M.: Statistical Image Reconstruction for Inconsistent CT Projection Data, Methods of Information in Medicine, 46(3), 261-269, 2007, DOI: 10.1160/me9041.
  [ BibTeX ] [ URL ]
   
  @article{Oehler2007a, author = {Buzug, Thorsten and Oehler, May}, journal = {Methods of Information in Medicine}, keywords = {BuzugThorsten IMT MetalArtefactReduction}, number = 3, pages = {261-269}, publisher = {Schattauer {GmbH}}, title = {Statistical Image Reconstruction for Inconsistent {CT} Projection Data}, volume = 46, year = 2007 }
• Schneider, S., Buzug, T. M., Weber, S. and Gundlich, B.: Accuracy of Scatter Estimation Methods for Different High-Resolution PET Systems, Computer Assisted Radiology and Surgery, 2(1:1), 469, 2007, DOI: 10.1007/s11548-007-0113-5.
  [ BibTeX ] [ URL ]
   
  @article{Schneider2007, author = {Schneider, S. and Buzug, T. M. and Weber, S. and Gundlich, B.}, journal = {Computer Assisted Radiology and Surgery}, keywords = {BuzugThorsten IMT}, number = {1:1}, pages = 469, title = {Accuracy of Scatter Estimation Methods for Different High-Resolution PET Systems}, volume = 2, year = 2007 }
• Bongartz, J. and Buzug, T. M.: Die Gesichtsweichteilrekonstruktion - Vorbereitung, Durchführung und Bewertung, Zeitschrift für Kriminalistik, 10(60), 588-593, 2006.
  [ BibTeX ]
   
  @article{Bongartz2006, author = {Bongartz, J. and Buzug, T. M.}, journal = {Zeitschrift für Kriminalistik}, keywords = {BuzugThorsten IMT}, number = 60, pages = {588-593}, title = {Die Gesichtsweichteilrekonstruktion - Vorbereitung, Durchführung und Bewertung}, volume = 10, year = 2006 }
• Buzug, T. M. and von Berg, A.: Micro-CT Bildgebung an Zähnen des frühen Mittelpaläolithikums aus der Kratermulde des Schweinskopfes bei Bassenheim, Kr. Mayen - Koblenz, Berichte zur Archäologie an Mittelrhein und Mosel, 11, 9-19, 2006.
  [ BibTeX ]
   
  @article{Buzug2006i, author = {Buzug, T. M. and von Berg, A.}, journal = {Berichte zur Archäologie an Mittelrhein und Mosel}, keywords = {BuzugThorsten IMT NDT Neandertaler}, pages = {9-19}, title = {Micro-CT Bildgebung an Zähnen des frühen Mittelpaläolithikums aus der Kratermulde des Schweinskopfes bei Bassenheim, Kr. Mayen - Koblenz}, volume = 11, year = 2006 }
• Buzug, T. M.: Special Issue on Computer-Assisted Craniofacial Reconstruction and Modeling, Journal of Computing and Information Technology, 14(1), 1, 2006, DOI: 10.2498/cit.2006.01.01.
  [ BibTeX ] [ URL ]
   
  @article{Buzug_2006, author = {Buzug, Thorsten M.}, journal = {Journal of Computing and Information Technology}, keywords = {BuzugThorsten IMT}, number = 1, pages = 1, publisher = {University of Zagreb - University Computing Centre}, title = {Special Issue on Computer-Assisted Craniofacial Reconstruction and Modeling}, volume = 14, year = 2006 }
• Mang, A., Muller, J. and Buzug, T. M.: A Multi-Modality Computer-Aided Framework Towards Postmortem Identification, Journal of Computing and Information Technology, 14(1), 7, 2006, DOI: 10.2498/cit.2006.01.02.
  [ BibTeX ] [ URL ]
   
  @article{Mang2006b, author = {Mang, Andreas and Muller, Jan and Buzug, Thorsten M.}, journal = {Journal of Computing and Information Technology}, keywords = {BuzugThorsten IMT}, number = 1, pages = 7, publisher = {University of Zagreb - University Computing Centre}, title = {A Multi-Modality Computer-Aided Framework Towards Postmortem Identification}, volume = 14, year = 2006 }
• Buzug, T. M. and Bongartz, J.: Forensische Gesichtsrekonstruktion. Ein Überblick über forensische, anthropologische und chirurgische Fragestellungen, Zeitschrift für Kriminalistik, 8-9(60), 502-505, 2006.
  [ BibTeX ]
   
  @article{Buzug2006d, author = {Buzug, T. M. and Bongartz, J.}, journal = {Zeitschrift für Kriminalistik}, keywords = {BuzugThorsten Forensics IMT NDT Neandertaler}, number = 60, pages = {502-505}, title = {Forensische Gesichtsrekonstruktion. Ein Überblick über forensische, anthropologische und chirurgische Fragestellungen}, volume = {8-9}, year = 2006 }
• Nestler, B., Klein, S., Opp, A. and D.Wuttig,: Dosierung und Messung kleiner Volumenströme als Voraussetzung für die Realisierung eines implantierbaren Mikroinfusionssystems, Impulse, 10, 65–73, 2005.
  [ BibTeX ]
   
  @article{opp2005a, author = {Nestler, B. and Klein, S. and Opp, A. and D.Wuttig}, journal = {Impulse}, keywords = {IMT}, pages = {65–73}, title = {Dosierung und Messung kleiner Volumenströme als Voraussetzung für die Realisierung eines implantierbaren Mikroinfusionssystems}, volume = 10, year = 2005 }

Book or Conference Proceedings [ to top ]

• Wei, H., Behrends, A., Friedrich, T. and Buzug, T.: A heating coil insert for a preclinical MPI scanner, International Journal on Magnetic Particle Imaging, , Suppl. 1, 2020, DOI: doi{10.18416/IJMPI.2020.2009056}.
  [ BibTeX ] [ URL ]
   
  @proceedings{https://doi.org/10.18416/ijmpi.2020.2009056, abstract = {Magnetic particle imaging (MPI) is a rapidly developing imaging modality, which determines the spatial distribution of magnetic nanoparticles. Magnetic fluid hyperthermia (MFH) is a promising therapeutic approach where magnetic nanoparticles are used to transform electromagnetic energy into heat. The similarities of MPI and MFH give rise to the potential of integration of MFH and MPI. In our previous work, a heating coil insert for the preclinical MPI scanner is designed, which can be utilized to generate a high frequency magnetic field suitable for MFH. The current development of the heating coil insert is presented in this paper.}, author = {Wei, Huimin and Behrends, Andre and Friedrich, Thomas and Buzug, Thorsten}, journal = {International Journal on Magnetic Particle Imaging}, keywords = {buzugthorsten imt mpi weihuimin}, number = 3, pages = {Suppl. 1}, publisher = {International Journal on Magnetic Particle Imaging}, title = {A heating coil insert for a preclinical MPI scanner}, volume = 6, year = 2020 }
• Ahlborg, M.: Bildgebungskonzepte für Magnetic Particle Imaging Bildgebungskonzepte und Rekonstruktionsansätze für große Bildgebungsvolumen bei Magnetic Particle Imaging, Infinite Science Publishing, Lübeck, 2016, ISBN: 9783945954157 3945954150.
  [ BibTeX ] [ URL ]
   
  @book{ahlborg2016bildgebungskonzepte, address = {Lübeck}, author = {Ahlborg, Mandy}, keywords = {MPITheo ahlborgmandy imt}, publisher = {Infinite Science Publishing}, title = {Bildgebungskonzepte für Magnetic Particle Imaging Bildgebungskonzepte und Rekonstruktionsansätze für große Bildgebungsvolumen bei Magnetic Particle Imaging}, year = 2016 }
• Gräfe, K.: Bildgebungskonzepte für Magnetic Particle Imaging Magnetic Particle Imaging mit einer asymmetrischen Spulentopologie, Infinite Science Publishing, Lübeck, 2016, ISBN: 978-3-945954-27-0.
  [ BibTeX ]
   
  @book{grafe2016bildgebungskonzepte, address = {Lübeck}, author = {Gräfe, Ksenija}, keywords = {GraefeKsenija IMT MPI SingleSided}, publisher = {Infinite Science Publishing}, title = {Bildgebungskonzepte für Magnetic Particle Imaging Magnetic Particle Imaging mit einer asymmetrischen Spulentopologie}, year = 2016 }
• Dössel, O. and Buzug, T. M.: Biomedizinische Technik - Band 7: Medizinische Bildgebung, De Gruyter, Berlin, 2014, ISBN: 9783110252057.
  [ BibTeX ] [ URL ]
   
  @book{Buzug2013b, address = {Berlin}, author = {Dössel, Olaf and Buzug, T.M.}, keywords = {BuzugThorsten IMT}, publisher = {De Gruyter}, title = {Biomedizinische Technik - Band 7: Medizinische Bildgebung}, year = 2014 }
• Buzug, T. M. (Ed.): Proceedings of the 2nd Student Conference Medical Engineering Science 2013, Grin Verlag, München, 2013, ISBN: 9783656381938.
  [ BibTeX ] [ URL ]
   
  @book{Buzug2013a, address = {München}, editor = {Buzug, T.M.}, keywords = {BuzugThorsten IMT}, publisher = {Grin Verlag}, title = {Proceedings of the 2nd Student Conference Medical Engineering Science 2013}, year = 2013 }
• Buzug, T. M. and Borgert, J. (Eds.): MagneticParticle Imaging: A Novel SPIO Nanoparticle Imaging Technique, Springer, Berlin; New York, 2012, ISBN: 9783642241321.
  [ BibTeX ] [ URL ]
   
  @book{Buzug2012, abstract = {Magnetic Particle Imaging (MPI) is a novel imaging modality. In MPI superparamagnetic iron oxide nanoparticles are used as tracer materials. The volume is the proceeding of the 2nd international workshop on magnetic particle imaging (IWMPI). The workshop aims at covering the status and recent developments of both, the instrumentation and the tracer material, as each of them is equally important in designing a well performing MPI. For instance, the current state of the art in magnetic coil design for MPI is discussed. With a new symmetrical arrangement of coils, a field-free line (FFL) can be produced that promises a significantly higher sensitivity compared with the standard arrangement for a FFP. Furthermore, the workshop aims at presenting results from phantom and pre-clinical studies.}, address = {Berlin; New York}, editor = {Buzug, T. M. and Borgert, J.}, keywords = {BuzugThorsten IMT}, publisher = {Springer}, title = {MagneticParticle Imaging: A Novel SPIO Nanoparticle Imaging Technique}, year = 2012 }
• Buzug, T. M. (Ed.): Proceedings of the 1st Student Conference on Medical Engineering Science 2012, Grin, München, 2012, ISBN: 9783656264187.
  [ BibTeX ] [ URL ]
   
  @book{Buzug2012c, address = {München}, editor = {Buzug, T. M.}, keywords = {BuzugThorsten IMT}, publisher = {Grin}, title = {Proceedings of the 1st Student Conference on Medical Engineering Science 2012}, year = 2012 }
• Buzug, T. M. and Knopp, T.: MagneticParticle Imaging: An Introduction to Imaging Principles and Scanner Instrumentation, Springer, Berlin/Heidelberg, 2012, ISBN: 9783642041990.
  [ BibTeX ] [ URL ]
   
  @book{Knopp2012, abstract = {"This volume provides a comprehensive overview of recent developments in magnetic particle imaging (MPI), a novel imaging modality. Using various static and oscillating magnetic fields, and tracer materials made from iron oxide nanoparticles, MPI can perform background-free measurements of the particles{u2019} local concentration. The method exploits the nonlinear remagnetization behavior of the particles and has the potential to surpass current methods for the detection of iron oxide in terms of sensitivity and spatiotemporal resolution. Starting from an introduction to the technology, the topics addressed include setting up an imaging device, assessment of image quality, development of new MPI tracer materials, and the first preclinical results. This is the first book to be published on magnetic particle imaging, and it will be an invaluable source of information for everyone with an interest in this exciting new modality."--Publisher's website.}, address = {Berlin/Heidelberg}, author = {Buzug, T.M. and Knopp, T.}, keywords = {BuzugThorsten IMT}, publisher = {Springer}, title = {MagneticParticle Imaging: An Introduction to Imaging Principles and Scanner Instrumentation}, year = 2012 }
• Becker, S., Popp, K., Mang, A., Schuetz, T. A., Toma, A., Dunst, J., Buzug, T. M. and Rades, D.: A New Mathematical Model to Simulate the Progression of Brain Metastasis, 297-298, 2012, DOI: 10.1016/j.ijrobp.2012.07.777.
  [ BibTeX ] [ URL ]
   
  @proceedings{Becker:2012c, author = {Becker, S. and Popp, K. and Mang, A. and Schuetz, T. A. and Toma, A. and Dunst, J. and Buzug, T. M. and Rades, D.}, booktitle = {International Journal of Radiation Oncology, Biology, Physics}, keywords = {BeckerStefan BuzugThorsten IMT TumorSimulation}, number = {3:Suppl.}, pages = {297-298}, title = {A New Mathematical Model to Simulate the Progression of Brain Metastasis}, volume = 84, year = 2012 }
• Buzug, T. M., Borgert, J., Knopp, T., Biederer, S., Sattel, T. F., Erbe, M. and Lüdtke-Buzug, K. (Eds.): Magnetic Nanoparticles: Particle Science, Imaging Technology and Clinical Applications, World Scientific Publishing Company, Singapore; Hackensack, N.J., 2010, ISBN: 9789814324687.
  [ BibTeX ] [ URL ]
   
  @book{Buzug2010, abstract = {In these proceedings, an overview on recent results of a novel imaging modality based on magnetic nanoparticles is given. This imaging concept, called magnetic particle imaging (MPI), falls into the category of functional imaging and, hence, the magnetic nanoparticles may serve as tracers of metabolic processes. Today, there are interesting challenges within the practical set-up of a scanning device and also in the design of new MPI nanoparticles. During this workshop at the University of Lubeck in 2010, scientists from chemical engineering, biology, electrical engineering, physics, computer s.}, address = {Singapore; Hackensack, N.J.}, editor = {Buzug, T. M. and Borgert, J. and Knopp, T. and Biederer, S. and Sattel, T.F. and Erbe, M. and Lüdtke-Buzug, K.}, keywords = {BuzugThorsten IMT}, publisher = {World Scientific Publishing Company}, title = {Magnetic Nanoparticles: Particle Science, Imaging Technology and Clinical Applications}, year = 2010 }
• Buzug, T. M., Biederer, S., Borgert, J., Erbe, M., Knopp, T. and Lüdtke-Buzug, K.: 1st International Workshop on Magnetic Particle Imaging (IWMPI 2010) - Book of Abstracts, Verlags- und Druckhaus Max Schmidt-Römhild KG, Lübeck, 2010, ISBN: 9783795070762.
  [ BibTeX ] [ URL ]
   
  @book{Buzug2010a, address = {Lübeck}, author = {Buzug, T. M. and Biederer, S. and Borgert, J. and Erbe, M. and Knopp, T. and Lüdtke-Buzug, K.}, editor = {Sattel, T. F.}, keywords = {BuzugThorsten IMT LuedtkeKerstin}, publisher = {Verlags- und Druckhaus Max Schmidt-Römhild KG}, title = {1st International Workshop on Magnetic Particle Imaging (IWMPI 2010) - Book of Abstracts}, year = 2010 }
• Buzug, T. M.: Computed Tomography: From Photon Statistics to Modern Cone-Beam CT, Springer, Berlin, 2010, DOI: 10.1007/978-3-540-39408-2.
  [ BibTeX ] [ URL ]
   
  @book{Buzug2008a, address = {Berlin}, author = {Buzug, Thorsten M.}, keywords = {BuzugThorsten IMT MetalArtefactReduction NDT}, publisher = {Springer}, title = {Computed Tomography: From Photon Statistics to Modern Cone-Beam CT}, year = 2010 }

Patent [ to top ]

• Schumacher, J., Neumann, A., Malhotra, A., Behrends, A. and Buzug, T.: Verfahren zur Erfassung der magnetischen Antwort einer Verteilung magnetisierbarer Partikel auf ein magnetisches Anregungsfeld, 2022, DE 10 2020 118 102 B4.
  [ BibTeX ]
   
  @patent{schumacher2022verfahren, annote = {DE 10 2020 118 102 B4}, author = {Schumacher, Jonas and Neumann, Alexander and Malhotra, Ankit and Behrends, André and Buzug, Thorsten}, keywords = {behrendsandre buzugthorsten imt malhotraankit mpi myown neumannalexander schumacherjonas}, title = {Verfahren zur Erfassung der magnetischen Antwort einer Verteilung magnetisierbarer Partikel auf ein magnetisches Anregungsfeld}, year = 2022 }
• Beuke, J., Buzug, T., Friedrich, T., Rostalski, P. and Gräser, M.: Verfahren zur Magnetpartikelbildgebung mit verbesserter Messdynamik, German Patent, 2019, DE 10 2018 204 311 B3.
  [ BibTeX ]
   
  @patent{beuke2019verfahren, annote = {DE 10 2018 204 311 B3}, author = {Beuke, Jonas and Buzug, Thorsten and Friedrich, Thomas and Rostalski, Philipp and Gräser, Matthias}, keywords = {beukejonas buzugthorsten friedrichthomas graesermatthias imt mpi schumacherjonas}, month = {may}, note = {German}, title = {Verfahren zur Magnetpartikelbildgebung mit verbesserter Messdynamik}, year = 2019 }
• Kaethner, C., Bringout, G., Grüttner, M., Weber, M. and Buzug, T. M.: Method for magnetic particle imaging having unlimited axial field of view, International Patent, 2013, EP13802304.9.
  [ BibTeX ]
   
  @patent{kaethner2013method, annote = {EP13802304.9}, author = {Kaethner, Christian and Bringout, Gael and Grüttner, Mandy and Weber, Matthias and Buzug, Thorsten M.}, keywords = {ahlborgmandy buzugthorsten imt mpi}, note = {International}, title = {Method for magnetic particle imaging having unlimited axial field of view}, year = 2013 }