Dr.-Ing. Ksenija Gräfe

Institut für Medizintechnik

Universität zu Lübeck
Ratzeburger Allee 160
23562 Lübeck
Gebäude 64, Raum 060

Email:graefe(at)imt.uni-luebeck.de
Phone:+49 451 3101 5424
Fax:+49 451 3101 5404

Role

Research Scientist


Research

Research Interests

  • Magnetic Particle Imaging (MPI)
  • Biomedical Signal Processing

Involved Projects

  • Magnetic Particle Imaging

Current Aspects of Research

  • Improving the single-sided MPI scanner
  • Comparing different simulation tools

Teaching

Involved Lectures, Seminars and Courses


Curriculum Vitae

KSENIJA GRÄFE was born in Düsseldorf, Germany in 1986. In 2009 she received her B.Sc. in Electrical Engineering and Information Technology from the University of Duisburg-Essen, Germany. In 2009 she wrote her bachelor thesis at the Fraunhofer Institute for Microelectronic Circuits and Systems. She received her M.Sc. in Biomedical Engineering from the Leibniz University Hannover, Germany, in 2011. In 2010/2011 she finished her university studies with the master thesis, which she wrote at the Institute of Biomedical Engineering, Karlsruhe. Since 08/2011 she joined the Magnetic Particle Imaging (MPI) group as a research assistant at the Institute of Medical Engineering, Lübeck.


Publications

[ 2019 ] [ 2018 ] [ 2016 ] [ 2015 ] [ 2014 ] [ 2013 ] [ 2012 ] [ 2011 ]

2019 [ to top ]

  • von Gladiss, A., Blancke Soares, Y., Buzug, T. M. and Gräfe, K.: Dynamic Imaging with a 3D Single-Sided MPI Scanner, In: International Workshop on Magnetic Particle Imaging, 2019.
     

2018 [ to top ]

  • Weber, M., Beuke, J., von Gladiss, A., Gräfe, K., Vogel, P., Behr, V. C. and Buzug, T. M.: Novel Field Geometry Using Two Halbach Cylinders for FFL-MPI, International Journal on Magnetic Particle Imaging, 4(1), 2018, DOI: 10.18416/IJMPI.2018.1811004.
     
  • Gräfe, K., von Gladiss, A. and Buzug, T. M.: First Phantom Measurements with a 3D Single Sided MPI Scanner, In: International Workshop on Magnetic Particle Imaging, 2018.
     

2016 [ to top ]

  • Blancke Soares, Y., von Gladiss, A., Ahlborg, M., Gräfe, K. and Buzug, T. M.: Comparison of Frequency Selection Methods for Image Reconstruction in Magnetic Particle Imaging - Improving Image Quality -, In: Student Conference Medical Engineering Science, 221-224, 2016.
     
  • Bringout, G., Gräfe, K. and Buzug, T. M.: MPI System Matrix Reconstruction: Making Assumptions on the Imaging Device rather than on the Tracer Spatial Distribution, In: International Workshop on Magnetic Particle Imaging, 174, 2016.
     
  • Gräfe, K., von Gladiss, A., Ahlborg, M., Bringout, G. and Buzug, T. M.: Reconstruction of a 2D Phantom Recorded with a Single-Sided MPI Device, In: International Workshop on Magnetic Particle Imaging, 23, 2016.
     
  • Gräfe, K., von Gladiß, A., Bringout, G., Ahlborg, M. and Buzug, T. M.: 2D Images Recorded With a Single-Sided Magnetic Particle Imaging Scanner, IEEE Transactions on Medical Imaging, 35(4), 1056-1065, 2016, DOI: 10.1109/TMI.2015.2507187.
     

2015 [ to top ]

  • Graeser, M., Ahlborg, M., Behrends, A., Bente, K., Bringout, G., Debbeler, C., v. Gladiß, A., Gräfe, K., Kaethner, C., Kaufmann, S., Lüdtke-Buzug, K., Medimagh, H., Stelzner, J., Weber, M. and Buzug, T. M.: A Device for Measureing the Trajectorey Dependent Magnetic Particle Performance for MPI, In: International Workshop on Magnetic Particle Imaging, 2015, DOI: 10.1109/IWMPI.2015.7107078.
     
  • Finas, D., Stegemann-Frehse, J., Sauer, B., Hüttmann, G., Gräfe, K., Rody, A., Buzug, T. M. and Lüdtke-Buzug, K.: SPIO processing in macrophages for MPI - the breast cancer MPI-SNLB-concept, In: Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung, 228, 2015, DOI: 10.1515/bmt-2015-5010.
     
  • Medimagh, H., Weissert, P., Bringout, G., Bente, K., Weber, M., Gräfe, K., Cordes, A. and Buzug, T. M.: Artifacts in field free line magnetic particle imaging in the presence of inhomogeneous and nonlinear magnetic fields, Current Directions in Biomedical Engineering, 1(1), 245-248, 2015, DOI: 10.1515/cdbme-2015-0061.
     
  • Medimagh, H., Weissert, P., Bringout, G., Bente, K., Weber, M., Gräfe, K., Cordes, A. and Buzug, T. M.: Artifacts in Field Free Line Magnetic Particle Imaging in the Presence of Inhomogeneous and Nonlinear Magnetic Fields, In: Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung, 2015.
     
  • Bringout, G., Gräfe, K. and Buzug, T. M.: Performance and safety evaluation of a human sized FFL imager concept, In: International Workshop on Magnetic Particle Imaging, 37, 2015.
     
  • v. Gladiß, A., Gräfe, K., Ahlborg, M. and Buzug, T. M.: Undersampling the system matrix of a single sided MPI-scanner, In: International Workshop on Magnetic Particle Imaging, 2015, DOI: 10.1109/IWMPI.2015.7107021.
     
  • Bringout, G., Gräfe, K. and Buzug, T. M.: Performance of Shielded Electromagnet-Evaluation Under Low-Frequency Excitation, IEEE Transactions on Magnetics, 51(2), 1-4, 2015, DOI: 10.1109/TMAG.2014.2329396.
     
  • Medimagh, H., Weissert, P., Bringout, G., Bente, K., Weber, M., Gräfe, K., Cordes, A. and Buzug, T. M.: Artifacts in field free line magnetic particle imaging, In: International Workshop on Magnetic Particle Imaging, 2015, DOI: 10.1109/IWMPI.2015.7107043.
     
  • Kaethner, C., Ahlborg, M., Gräfe, K., Bringout, G., Sattel, T. F. and Buzug, T. M.: Asymmetric Scanner Design for Interventional Scenarios in Magnetic Particle Imaging, IEEE Transactions on Magnetics, 51(2), 1-4, 2015, DOI: 10.1109/TMAG.2014.2337931.
     
  • Gräfe, K., Bringout, G., Graeser, M., Sattel, T. F. and Buzug, T. M.: System Matrix Recording and Phantom Measurements with a Single-Sided Magnetic Particle Imaging Device, IEEE Transactions on Magnetics, 51(2), 6502303, 2015, DOI: 10.1109/TMAG.2014.2330371.
     
  • Finas, D., Baumann, K., Sydow, L., Heinrich, K., Rody, A., Gräfe, K., Buzug, T. M. and Lüdtke-Buzug, K.: SPIO Detection and Distribution in Biological Tissue - A Murine MPI-SLNB Breast Cancer Model, IEEE Transactions on Magnetics, 51(2), 5400104, 2015, DOI: 10.1109/TMAG.2014.2358272.
     
  • Gräfe, K., v. Gladiß, A., Bringout, G., Ahlborg, M. and Buzug, T. M.: 2D Imaging with a Single-Sided MPI Device, In: International Workshop on Magnetic Particle Imaging, 2015, DOI: 10.1109/IWMPI.2015.7107024.
     

2014 [ to top ]

  • Baumann, K., Stegmann-Frehse, J., Rody, A., Gräfe, K., Lüdtke-Buzug, K., Buzug, T. and Finas, D.: Weiterentwicklung des SNLB-Konzept unter Verwendung von SPIOs beim Mammakarzinom - Prozessierung der Nanopartikel im Organismus, Senologie, 11-A13, 2014, DOI: 10.1055/s-0034-1375372.
     
  • Lindemann, A., Lüdtke-Buzug, K., Fraederich, B. M., Gräfe, K., Pries, R. and Wollenberg, B.: Biological impact of superparamagnetic iron oxide nanoparticles for magnetic particle imaging of head and neck cancer cells, International Journal of Nanomedicine, 9, 5025–5040, 2014, DOI: 10.2147/ijn.s63873.
     
  • Gräfe, K., Bringout, G., Graeser, M., Sattel, T. F. and Buzug, T. M.: Single-Sided Magnetic Particle Imaging Scanner: System Matrix Measurement, In: Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung, 638-642, 2014, DOI: 10.1515/bmt-2014-5009.
     
  • Finas, D., Baumann, K., Stegemann-Frehse, J., Gräfe, K., Rody, A., Buzug, T. M. and Lüdtke-Buzug, K.: Processing of nanoparticles in organism - further development of the breast cancer SNLB-concept using SPIOs and MPI, In: Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung, 314, 2014, DOI: 10.1515/bmt-2014-5003.
     
  • Gräfe, K., Bringout, G., Graeser, M., Sattel, T. F. and Buzug, T. M.: System Matrix Recording and Phantom Measurements with a Single-Sided Magnetic Particle Imaging Device, In: International Workshop on Magnetic Particle Imaging, 92, 2014.
     
  • Wojtczyk, H., Bringout, G., Tenner, W., Graeser, M., Grüttner, M., Sattel, T. F., Gräfe, K. and Buzug, T. M.: Toward the Optimization of D-Shaped Coils for the Use in an Open Magnetic Particle Imaging Scanner, IEEE Transactions on Magnetics, 50(7), 5100507, 2014, DOI: 10.1109/TMAG.2014.2303113.
     
  • Kaethner, C., Gräfe, K., Ahlborg, M., Bringout, G., Sattel, T. F. and Buzug, T. M.: Asymmetric Scanner Design for Unlimited Patient Access in Magnetic Particle Imaging, In: International Workshop on Magnetic Particle Imaging, 84-85, 2014.
     
  • Kaethner, C., Ahlborg, M., Gräfe, K., Bringout, G., Sattel, T. F. and Buzug, T. M.: On the way to a patient table integrated scanner system in magnetic particle imaging, In: SPIE Medical Imaging, 903816, 2014, DOI: 10.1117/12.2042765.
     
  • Finas, D., Baumann, K., Sydow, L., Heinrich, K., Rody, A., Gräfe, K., Buzug, T. M. and Lüdtke-Buzug, K.: SPIO detection and distribution in biological tissue – a murine MPI-SNLB breast cancer model, In: International Workshop on Magnetic Particle Imaging, 166, 2014.
     

2013 [ to top ]

  • Gräfe, K., Weber, M., Sattel, T. F. and Buzug, T. M.: Precision of an MPI Scanner Construction: Registration of Measured and Simulated Magnetic Fields, In: Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung, 2013, DOI: 10.1515/bmt-2013-4258.
     
  • Gräfe, K., Mrongowius, J. and Buzug, T. M.: Simulation of a Single-Sided Magnetic Particle Imaging Device with Comsol, In: Comsol Conference, 2013.
     
  • Bente, K., Bringout, G., Debbeler, C., Gräfe, K., Graeser, M., Grüttner, M., Kaethner, C., Tenner, W., Weber, M., Wojtczyk, H., Buzug, T. M. and Lüdtke-Buzug, K.: Magnetic Particle Imaging - eine Einführung in die Instrumentierung und Bildrekonstruktion, In: Proceedings der 44. Jahrestagung der Deutschen Gesellschaft für Medizinische Physik, 95-100, 2013.
     
  • Mrongowius, J., Gräfe, K. and Buzug, T. M.: Simulation Study of a Single-Sided Magnetic Particle Imaging Device, In: Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung, 2013, DOI: 10.1515/bmt-2013-4285.
     
  • Wojtczyk, H., Bringout, G., Tenner, W., Graeser, M., Grüttner, M., Sattel, T. F., Gräfe, K., Haegele, J., Duschka, R. L., Panagiotopoulos, N., Vogt, F. M., Barkhausen, J. and Buzug, T. M.: Comparison of Open Scanner Designs for Interventional Magnetic Particle Imaging, In: Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung, 2013, DOI: 10.1515/bmt-2013-4279.
     
  • Finas, D., Baumann, K., Sydow, L., Heinrich, K., Gräfe, K., Rody, A., Lüdtke-Buzug, K. and Buzug, T. M.: Superparamagnetic nanoparticles in lymphatic tissue - Detection and distribution in a breast cancer model for magnetic particle imaging, In: International Workshop on Magnetic Particle Imaging, 2013, DOI: 10.1109/IWMPI.2013.6528390.
     
  • Kaethner, C., Gräfe, K., Grüttner, M. and Buzug, T. M.: Approximated elliptical coils in magnetic particle imaging, In: International Workshop on Magnetic Particle Imaging, 2013, DOI: 10.1109/IWMPI.2013.6528343.
     
  • Gräfe, K., Grüttner, M., Sattel, T. F., Kaethner, C. and Buzug, T. M.: Phantom simulation based on measured gradient fields of a single-sided MPI scanner, In: International Workshop on Magnetic Particle Imaging, 2013, DOI: 10.1109/IWMPI.2013.6528352.
     
  • Gräfe, K., Grüttner, M., Sattel, T. F., Graeser, M. and Buzug, T. M.: Single-sided magnetic particle imaging: magnetic field and gradient, In: SPIE Medical Imaging, 867219, 2013, DOI: 10.1117/12.2001610.
     

2012 [ to top ]

  • Gräfe, K., Sattel, T. F., Lüdtke-Buzug, K., Finas, D., Borgert, J. and Buzug, T. M.: Magnetic-Particle-Imaging for Sentinel Lymph Node Biopsy in Breast Cancer, In: Springer Proceedings in Physics, 237-241, 2012, DOI: 10.1007/978-3-642-24133-8_38.
     
  • Finas, D., Baumann, K., Heinrich, K., Ruhland, B., Sydow, L., Gräfe, K., Sattel, T. F., Lüdtke-Buzug, K. and Buzug, T. M.: Distribution of Superparamagnetic Nanoparticles in Lymphatic Tissue for Sentinel Lymph Node Detection in Breast Cancer by Magnetic Particle Imaging, In: Springer Proceedings in Physics, 187-191, 2012, DOI: 10.1007/978-3-642-24133-8_30.
     
  • Buzug, T. M., Bringout, G., Erbe, M., Gräfe, K., Graeser, M., Grüttner, M., Halkola, A., Sattel, T. F., Tenner, W., Wojtczyk, H., Haegele, J., Vogt, F. M., Barkhausen, J. and Lüdtke-Buzug, K.: Magnetic particle imaging: Introduction to imaging and hardware realization, Zeitschrift für Medizinische Physik, 22(4), 323-334, 2012, DOI: 10.1016/j.zemedi.2012.07.004.
     
  • Gräfe, K., Sattel, T. F., Lüdtke-Buzug, K., Finas, D., Borgert, J. and Buzug, T. M.: An Application Scenario for Single-Sided Magnetic Particle Imaging, In: Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung, 514, 2012, DOI: 10.1515/bmt-2012-4343.
     
  • Finas, D., Baumann, K., Sydow, L., Heinrich, K., Gräfe, K., Buzug, T. M. and Lüdtke-Buzug, K.: Detection and distribution of superparamagnetic nanoparticles in lymphatic tissue in a breast cancer model for magnetic particle imaging, In: Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung, 81-83, 2012, DOI: 10.1515/bmt-2012-4158.
     

2011 [ to top ]

  • Baas, T., Gräfe, K. and Doessel, O.: Automatic Analysis of the T-Wave in Holter-ECG to Detect Small Drug Induced Repolaristaion Changes of the Ventricles, In: Biomed Tech, 2011.
     
  • Baas, T., Gräfe, K., Khawaja, A. and Dossel, O.: Investigation of parameters highlighting drug induced small changes of the T-wave's morphology for drug safety studies, In: Proceedings of the 33rd IEEE conference on Engineering in Medicine and Biology Society, 3796-3799, 2011, DOI: 10.1109/IEMBS.2011.6090769.