PMI - RTF VII: Multiscale imaging / Small animal PET/CT

This project is part of the DFG Exzellenzcluster Precision Medicine in Chronic Inflammation (PMI). The goal of RTF VII is to investigate new approaches for a better and more accurate imaging using positron emission tomography (PET), magnetic resonance imaging (MRI), and advanced optical imaging with lasers. The new imaging systems are aimed to support the study of inflammatory diseases.

Focus of the research project is the development of a reconstruction strategy to process two raw data sets of the same object from different modalities in one reconstruction formulation and therefore facilitate mutual assistance of both imaging techniques. This should enhance the results with respect to contrast, object boundaries and noise statistics.


  • The project is financially supported by the German Research Foundation (DFG) under grant agreement no. 390884018


2023[ to top ]
  • Vo, H., Seeger, S., Werner, J. and Rafecas, M.: Towards Full-body Small Aquatic Animal PET: a Simulation Study of MERMAID-v2, 1–1, 2023, DOI: 10.1109/NSSMICRTSD49126.2023.10338525.
  • Seeger, S., Vo, H., Florack, C., Werner, J., Schmidt, C. and Rafecas, M.: First Images from MERMAID, a Small Aquatic Animal PET Scanner Prototype, 1–1, 2023, DOI: 10.1109/NSSMICRTSD49126.2023.10338697.
  • Elmoujarkach, E., Seeger, S., Schmidt, C., Mannheim, J. G., Schmidt, F. P. and Rafecas, M.: First 3D printed radioactive 89Zr phantoms for Positron Emission Tomography, Transactions on Additive Manufacturing Meets Medicine, Vol. 5 No. S1 (2023): Trans. AMMM Supplement, 2023, DOI: 10.18416/AMMM.2023.2309833.
2022[ to top ]
  • Elmoujarkach, E., Seeger, S., Schareck, C., De Graaf, L., Barkhausen, J. and Rafecas, M.: Characterization of Using Infused PLA for 3DPrinted Radiation Shielding, Current Directions in Biomedical Engineering, 8(2), 2022, DOI:
  • Seeger, S., Vo, H. P., Bolke, A. and Rafecas, M.: Characterisation of the Upgraded MERMAID Prototype, a PET/CT Device for Small Aquatic Animals, 1–2, 2022, DOI: 10.1109/NSS/MIC44845.2022.10399085.
  • Zvolsky, M. L., Schaar, M., Seeger, S. S., Rakers, S. and Rafecas, M.: Development of a digital zebrafish phantom and its application to dedicated small-fish PET, Physics in Medicine & Biology, 67(17), 175005, 2022, DOI: 10.1088/1361-6560/ac71ee.
  • Seeger, S., Elmoujarkach, E., Möller, N., Schmidt, C. and Rafecas, M.: 3D printed radioactive phantoms for Positron Emission Tomography, ID 640, 2022, DOI: 10.18416/AMMM.2022.2209640.