LUMEN (Luebeck Medical Engineering)

In urgent emergencies of the brain (stenosis, vascular deficiencies, aneurysms, etc.), 2D-DSA is the clinical standard. Unfortunately, this is only a qualitative method. The actual amount of blood flow and oxygen supply cannot be determined. To analyze the dynamics of the contrast bolus and embed in the 3D vessel topology, magnetic particle imaging (MPI) is used in this project. A novel MPI system is built making it possible to track the bolus of contrast agent in real time. This is based on a field-free line (FFL). The MPI image does not include any native tissue and requires a registration with the static 3D rotational angiography.

In this project most of the engineering is done in our lab. We build customized coils for the scanner, specialized filter hardware, shielding techniques and phantoms. Our aim is a real time MPI scanner featuring the field-free line technology.

Field-free line scanner at the Institute of Medical Engineering.

Grants

  • Federal Ministry of Education and Research under grant number BMBF 13EZ1140A

Cooperations

  • Prof. Dr. rer. nat. Henrik Botterweck (Institut für Medizinische Bildgebung, Fachochschule Lübeck)
  • Prof. Dr. med Dirk Petersen (Institut für Neuroradiologie, Universität zu Lübeck)
  • Dr.-Ing. Markus Kowarschik (Siemens Healthcare, Imaging & IT Division)

Publications

[ 2018 ] [ 2015 ] [ 2014 ] [ 2013 ]

2018[ to top ]

  • Weber, M., Beuke, J., von Gladiss, A., Gräfe, K., Vogel, P., Behr, V. C. and Buzug, T. M.: Novel Field Geometry Using Two Halbach Cylinders for FFL-MPI, International Journal on Magnetic Particle Imaging, 4(1), 2018, DOI: 10.18416/IJMPI.2018.1811004.
     

2015[ to top ]

  • Weber, M., Bente, K., Graeser, M., Sattel, T. F. and Buzug, T. M.: Implementation of a High-Precision 2-D Receiving Coil Set for Magnetic Particle Imaging, IEEE Transactions on Magnetics, 51(2), 6502404, 2015, DOI: 10.1109/TMAG.2014.2331987.
     

2014[ to top ]

  • Weber, M., Bente, K., Graeser, M., Sattel, T. F. and Buzug, T. M.: Technical Aspects of a Two Dimensional Rotatable Field Free Line Imager for Magnetic Particle Imaging, In: International Workshop on Magnetic Particle Imaging, 98, 2014.
     
  • Weber, M., Bente, K. and Buzug, T. M.: Insight in Scanner Construction for a Dynamical Field Free Line for Magnetic Particle Imaging, In: Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung, 2014.
     
  • Bente, K., Weber, M., Graeser, M., Sattel, T. F., Erbe, M. and Buzug, T. M.: Electronic Field Free Line Rotation and Relaxation Deconvolution in Magnetic Particle Imaging, IEEE Transactions on Medical Imaging, 34(2), 644-651, 2014, DOI: 10.1109/TMI.2014.2364891.
     

2013[ to top ]

  • Weber, M., Erbe, M., Bente, K., Sattel, T. F. and Buzug, T. M.: Scanner Construction for a Dynamic Field Free Line in Magnetic Particle Imaging, In: Deutsche Gesellschaft für Biomedizinische Technik Jahrestagung, 2013, DOI: 10.1515/bmt-2013-4259.
     
  • Weber, M., Erbe, M., Bente, K., Sattel, T. F. and Buzug, T. M.: Power loss optimized field free line generation for magnetic particle imaging, In: International Workshop on Magnetic Particle Imaging, 2013, DOI: 10.1109/IWMPI.2013.6528354.
     
  • Erbe, M., Weber, M., Sattel, T. F. and Buzug, T. M.: Experimental Validation of an Assembly of Optimized Curved Rectangular Coils for the use in Dynamic Field Free Line Magnetic Particle Imaging, Current Medical Imaging Reviews, 9(2), 89-95, 2013, DOI: 10.2174/1573405611309020003.